How is stomach cancer treated?

Written by Liu Liang
Oncology
Updated on September 21, 2024
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The treatment for gastric cancer now includes surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy, among others. The specific treatment plan is formulated based on various factors such as the staging of the cancer, the patient's overall condition, and the presence of any underlying diseases, which are all taken into consideration before deciding on a treatment plan. For patients in the early stages who are generally in good condition, surgical resection can be evaluated and is primarily curative. Post-operative treatment decisions, such as whether to pursue adjuvant radiotherapy or chemotherapy, depend on the pathology results and the presence of high-risk factors for recurrence. For patients in advanced stages who are found to have distant metastases upon diagnosis, treatment is primarily chemotherapy. Additionally, there are broad-spectrum targeted therapies against angiogenesis, such as apatinib, which are suitable for patients with advanced gastric cancer or those who do not respond well to chemotherapy, serving as a secondary or tertiary line of treatment. These are some of the treatment methods for gastric cancer. It is crucial that the use of any medication is conducted under the guidance of a doctor.

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Symptoms of gastric cancer

Symptoms of gastric cancer include nausea, vomiting, acid reflux, pain in the upper abdomen, and a sense of fullness and discomfort, especially after eating, which are some of the early symptoms. As the tumor progresses, symptoms can worsen, including pain, vomiting of blood, and black stools indicating upper gastrointestinal bleeding. If the tumor is near the pylorus, it can cause pyloric obstruction, which manifests as acid reflux followed by vomiting of undigested food from the previous night. In the late stages of gastric cancer, patients may experience fatigue, weight loss, severe cachexia, and anemia. These are symptoms of advanced gastric cancer.

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Is chemotherapy for gastric cancer torturous?

The first common side effect of chemotherapy drugs is gastrointestinal reactions, such as nausea, vomiting, decreased appetite, diarrhea, constipation, or bloating, and other such gastrointestinal symptoms. The second is bone marrow suppression, such as decreases in white blood cells and platelets; a decrease in white blood cells can easily lead to infections, and low platelets can lead to a tendency to bleed. There are also liver and kidney damage, numbness of hands and feet in the peripheral nervous system, and clinical symptoms such as fingernail darkening, pigmentation, or hand-foot syndrome caused by fluorouracil. The severity of chemotherapy side effects varies greatly among patients and is related to each patient's general condition, exhibiting significant individual differences. Some patients may experience severe reactions to chemotherapy, while others may have milder reactions. However, during chemotherapy, we provide corresponding symptomatic treatments such as gastric protection, antiemetics, and cardioprotection, among others, to try to minimize the side effects caused by chemotherapy.

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How to check for gastric cancer?

Gastroscopy is very important in the examination of gastric cancer, and taking a biopsy under gastroscopy is an important means of diagnosis. Other examinations include endoscopic ultrasound or enhanced abdominal CT and chest CT to assess the staging of the patient. With endoscopic ultrasound, we can see which layer of the stomach wall the tumor has invaded and then combine it with chest and abdominal CT scans to assess whether there is distant metastasis. Diagnosis requires gastroscopy with a biopsy taken during the procedure.

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How is gastric cancer caused?

The causes of gastric cancer are not yet clearly understood. However, its occurrence is associated with poor dietary habits, such as irregular eating—sometimes skipping a meal, sometimes overeating, not having meals on time—and consuming pickled food, barbecued junk food, and other unhealthy dietary practices. Additionally, smoking, alcohol consumption, infection with Helicobacter pylori, chronic gastric diseases such as atrophic gastritis, and genetic factors are all somewhat related to the development of this condition.

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Written by Liu Liang
Oncology
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What can someone with stomach cancer eat?

For the diet of stomach cancer patients, they should focus on eating easily digestible foods and maintain a balanced diet with frequent small meals. They can eat meat, eggs, vegetables, and fruits. However, they should avoid cancer-causing foods such as pickled products and barbecued foods, as well as overly greasy or hard-to-digest foods. There are no specific dietary prohibitions. As long as the patient has a good appetite and can tolerate food, they can eat many types of food.