Early symptoms of gastric cancer

Written by Wang Hui Jie
Gastroenterology
Updated on May 05, 2025
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The early symptoms of gastric cancer are not specific or characteristic in clinical presentations, and there are no specific signs either. It can also be said that there are no symptoms or signs at all. Some patients may be diagnosed with gastric cancer after presenting with symptoms of bleeding, such as vomiting blood, blood in stool, or black stools. Therefore, it is recommended for individuals over 40 years old to consider undergoing gastroscopy, especially if they experience discomfort or pain in the upper abdomen, weight loss, or have a history of poor gastric mucosa conditions seen in previous gastroscopies, including atrophy, intestinal metaplasia, or ulcers, as well as a history of testing positive for Helicobacter pylori. Regular follow-up gastroscopies are advised under these circumstances.

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Written by Liu Liang
Oncology
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Does early-stage stomach cancer hurt?

Symptoms of early-stage gastric cancer are generally not very obvious. Some patients may experience subtle symptoms resembling those of gastritis or gastrointestinal ulcers, including non-specific gastrointestinal symptoms such as discomfort and bloating in the upper abdomen, acid reflux, nausea, vomiting, and decreased appetite. In terms of pain, early-stage gastric cancer patients might only experience a sensation of bloating or mild tenderness in the upper abdomen. Severe pain is usually associated with late-stage gastric cancer, occurring when there is extensive abdominal metastasis or tumor progression, and the tumor is large enough to cause significant pain, requiring analgesics for treatment.

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Written by Liu Liang
Oncology
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How is gastric cancer caused?

The causes of gastric cancer are not yet clearly understood. However, its occurrence is associated with poor dietary habits, such as irregular eating—sometimes skipping a meal, sometimes overeating, not having meals on time—and consuming pickled food, barbecued junk food, and other unhealthy dietary practices. Additionally, smoking, alcohol consumption, infection with Helicobacter pylori, chronic gastric diseases such as atrophic gastritis, and genetic factors are all somewhat related to the development of this condition.

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Written by Liu Liang
Oncology
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Late-stage symptoms of gastric cancer

The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.

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Written by Zhou Zi Hua
Oncology
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Early symptoms of gastric cancer

The symptoms of early gastric cancer are nonspecific and similar to those of chronic gastritis, gastric ulcers, gastroparesis, and other benign diseases, making it difficult to distinguish. Screening data shows that 40%-60% of patients with early gastric cancer are asymptomatic. The symptoms of early gastric cancer primarily include pain or discomfort in the upper abdomen, loss of appetite, fatigue, vomiting, hematemesis, blood in stools, melena, and difficulty swallowing. Discomfort in the upper abdomen is the most common symptom, followed by pain beneath the sternum. Generally, early gastric cancer does not present specific physical signs, though tenderness in the upper abdomen is relatively common, and some patients may exhibit signs of anemia.

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Written by Liu Liang
Oncology
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Symptoms of gastric cancer

Symptoms of gastric cancer include nausea, vomiting, acid reflux, pain in the upper abdomen, and a sense of fullness and discomfort, especially after eating, which are some of the early symptoms. As the tumor progresses, symptoms can worsen, including pain, vomiting of blood, and black stools indicating upper gastrointestinal bleeding. If the tumor is near the pylorus, it can cause pyloric obstruction, which manifests as acid reflux followed by vomiting of undigested food from the previous night. In the late stages of gastric cancer, patients may experience fatigue, weight loss, severe cachexia, and anemia. These are symptoms of advanced gastric cancer.