Late-stage symptoms of gastric cancer

Written by Liu Liang
Oncology
Updated on September 05, 2024
00:00
00:00

The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.

Other Voices

doctor image
home-news-image
Written by Liu Liang
Oncology
1min 30sec home-news-image

Late-stage symptoms of gastric cancer

The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.

doctor image
home-news-image
Written by Liu Liang
Oncology
1min 17sec home-news-image

Is chemotherapy for gastric cancer torturous?

The first common side effect of chemotherapy drugs is gastrointestinal reactions, such as nausea, vomiting, decreased appetite, diarrhea, constipation, or bloating, and other such gastrointestinal symptoms. The second is bone marrow suppression, such as decreases in white blood cells and platelets; a decrease in white blood cells can easily lead to infections, and low platelets can lead to a tendency to bleed. There are also liver and kidney damage, numbness of hands and feet in the peripheral nervous system, and clinical symptoms such as fingernail darkening, pigmentation, or hand-foot syndrome caused by fluorouracil. The severity of chemotherapy side effects varies greatly among patients and is related to each patient's general condition, exhibiting significant individual differences. Some patients may experience severe reactions to chemotherapy, while others may have milder reactions. However, during chemotherapy, we provide corresponding symptomatic treatments such as gastric protection, antiemetics, and cardioprotection, among others, to try to minimize the side effects caused by chemotherapy.

doctor image
home-news-image
Written by Liu Liang
Oncology
1min 14sec home-news-image

Can stomach cancer be cured? Can stomach cancer be cured?

Early-stage gastric cancer patients can undergo curative surgery, and then decide whether postoperative adjuvant radiochemotherapy is needed based on the specific pathological type and the presence of high-risk recurrence factors. Through these treatments, a cure can be achieved. Generally, if there is no recurrence or metastasis within five years, it is considered cured. For example, patients in stage IA, even without adjuvant chemotherapy, have a relatively high five-year survival rate, generally above 90% after curative surgery. However, if it is found to be advanced-stage, such as initial detection showing distant metastases to the liver, lungs, etc., these patients are primarily treated with systemic chemotherapy or symptomatic palliative care. In such cases, a cure is not achievable. Therefore, whether a cure is possible depends on the stage of gastric cancer and factors such as the patient's basic physical condition.

doctor image
home-news-image
Written by Liu Liang
Oncology
49sec home-news-image

What is early-stage gastric cancer?

In the early stages of gastric cancer, the tumor is confined to the mucosa or submucosa, regardless of whether there is regional lymph node metastasis or not; this is still classified as early-stage gastric cancer. The treatment for early-stage gastric cancer primarily involves curative surgery, which is the first option unless the patient is of advanced age or has severe underlying diseases that prevent tolerance of surgical treatment. Excluding these cases, surgical treatment is generally the first choice. Furthermore, the outcome of surgical treatment for patients with early-stage gastric cancer is generally quite positive, with a five-year survival rate typically exceeding 80%.

doctor image
home-news-image
Written by Liu Liang
Oncology
58sec home-news-image

Can late-stage gastric cancer be treated?

Patients with late-stage gastric cancer generally may not have the opportunity for curative surgery, which is mainly suitable for early-stage gastric cancer patients. For late-stage gastric cancer patients, the treatment plan should be chosen based on the specific condition of the patient. If the patient's general condition is relatively good, chemotherapy can be an option. The type of chemotherapy, whether intravenous combination chemotherapy or oral drugs like tegafur capsules or capecitabine, which generally have milder reactions, depends on the patient's condition. Additionally, late-stage gastric cancer patients can try molecular targeted therapy, such as anti-angiogenesis drugs like apatinib, etc. Therefore, treatment options should be selected based on specific circumstances. The use of medications should be conducted under the guidance of a doctor.