Late-stage symptoms of gastric cancer

Written by Liu Liang
Oncology
Updated on September 05, 2024
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The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.

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Written by Liu Liang
Oncology
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Can late-stage gastric cancer be treated?

Patients with late-stage gastric cancer generally may not have the opportunity for curative surgery, which is mainly suitable for early-stage gastric cancer patients. For late-stage gastric cancer patients, the treatment plan should be chosen based on the specific condition of the patient. If the patient's general condition is relatively good, chemotherapy can be an option. The type of chemotherapy, whether intravenous combination chemotherapy or oral drugs like tegafur capsules or capecitabine, which generally have milder reactions, depends on the patient's condition. Additionally, late-stage gastric cancer patients can try molecular targeted therapy, such as anti-angiogenesis drugs like apatinib, etc. Therefore, treatment options should be selected based on specific circumstances. The use of medications should be conducted under the guidance of a doctor.

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Written by Liu Liang
Oncology
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Mid-stage symptoms of gastric cancer

Symptoms of mid-stage gastric cancer can include nausea, vomiting, poor appetite, decreased food intake, and upper abdominal pain, as well as symptoms related to the digestive tract. Some patients may also experience black stool or even vomiting blood, which are symptoms of upper gastrointestinal bleeding. Additionally, there can be bloating and abdominal pain. If the tumor is located near the pylorus and causes pyloric obstruction, clinical symptoms will include vomiting, vomiting of overnight food, and resulting in gastric retention. This can lead to significant symptoms such as abdominal pain, bloating, acid reflux, and nausea.

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Written by Liu Liang
Oncology
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Early manifestations of gastric cancer

The early signs of gastric cancer may include nausea, vomiting, or mild acid reflux, which are symptoms similar to those of gastritis, stomach ulcers, or duodenal ulcers. Therefore, initially, these patients may not take their condition seriously, assuming they might just have gastritis or peptic ulcers. These are some of the early manifestations of gastric cancer, and some patients may also experience discomfort and a feeling of fullness after eating.

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Written by Liu Liang
Oncology
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Symptoms of gastric cancer

Symptoms of gastric cancer include nausea, vomiting, acid reflux, pain in the upper abdomen, and a sense of fullness and discomfort, especially after eating, which are some of the early symptoms. As the tumor progresses, symptoms can worsen, including pain, vomiting of blood, and black stools indicating upper gastrointestinal bleeding. If the tumor is near the pylorus, it can cause pyloric obstruction, which manifests as acid reflux followed by vomiting of undigested food from the previous night. In the late stages of gastric cancer, patients may experience fatigue, weight loss, severe cachexia, and anemia. These are symptoms of advanced gastric cancer.

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Written by Wang Hui Jie
Gastroenterology
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Early symptoms of gastric cancer

The early symptoms of gastric cancer are not specific or characteristic in clinical presentations, and there are no specific signs either. It can also be said that there are no symptoms or signs at all. Some patients may be diagnosed with gastric cancer after presenting with symptoms of bleeding, such as vomiting blood, blood in stool, or black stools. Therefore, it is recommended for individuals over 40 years old to consider undergoing gastroscopy, especially if they experience discomfort or pain in the upper abdomen, weight loss, or have a history of poor gastric mucosa conditions seen in previous gastroscopies, including atrophy, intestinal metaplasia, or ulcers, as well as a history of testing positive for Helicobacter pylori. Regular follow-up gastroscopies are advised under these circumstances.