Can late-stage gastric cancer be treated?

Written by Liu Liang
Oncology
Updated on March 16, 2025
00:00
00:00

Patients with late-stage gastric cancer generally may not have the opportunity for curative surgery, which is mainly suitable for early-stage gastric cancer patients. For late-stage gastric cancer patients, the treatment plan should be chosen based on the specific condition of the patient. If the patient's general condition is relatively good, chemotherapy can be an option. The type of chemotherapy, whether intravenous combination chemotherapy or oral drugs like tegafur capsules or capecitabine, which generally have milder reactions, depends on the patient's condition. Additionally, late-stage gastric cancer patients can try molecular targeted therapy, such as anti-angiogenesis drugs like apatinib, etc. Therefore, treatment options should be selected based on specific circumstances. The use of medications should be conducted under the guidance of a doctor.

Other Voices

doctor image
home-news-image
Written by Liu Liang
Oncology
1min 12sec home-news-image

What are the symptoms of gastric cancer?

The symptoms of gastric cancer patients are generally common gastrointestinal symptoms such as nausea, vomiting, acid reflux, and discomfort and bloating in the upper abdomen, especially aggravated after eating. As the condition progresses, symptoms may include vomiting blood or black stools. When the cancer invades surrounding organs, clinical symptoms such as abdominal effusion, abdominal distension, and pain may occur. If the tumor is located near the pylorus and causes pyloric obstruction, symptoms of pyloric obstruction will appear, such as gastric retention, acid reflux, and vomiting of overnight food. Additionally, if the tumor bleeds, it may cause severe vomiting of blood. Therefore, different stages of the disease present different symptoms. If gastric cancer progresses to the late stage with metastasis to distant organs, clinical manifestations corresponding to the sites of metastasis will also appear.

doctor image
home-news-image
Written by Zhou Zi Hua
Oncology
56sec home-news-image

Early symptoms of gastric cancer

The symptoms of early gastric cancer are nonspecific and similar to those of chronic gastritis, gastric ulcers, gastroparesis, and other benign diseases, making it difficult to distinguish. Screening data shows that 40%-60% of patients with early gastric cancer are asymptomatic. The symptoms of early gastric cancer primarily include pain or discomfort in the upper abdomen, loss of appetite, fatigue, vomiting, hematemesis, blood in stools, melena, and difficulty swallowing. Discomfort in the upper abdomen is the most common symptom, followed by pain beneath the sternum. Generally, early gastric cancer does not present specific physical signs, though tenderness in the upper abdomen is relatively common, and some patients may exhibit signs of anemia.

doctor image
home-news-image
Written by Liu Liang
Oncology
1min 30sec home-news-image

Late-stage symptoms of gastric cancer

The common late-stage symptoms of gastric cancer patients include nausea, vomiting, and even a complete inability to eat. There are also symptoms related to the digestive tract such as pain in the upper abdomen and acid reflux, as well as upper gastrointestinal bleeding, such as vomiting blood and melena which are signs of lower gastrointestinal bleeding. Late-stage gastric cancer patients may also experience organ metastasis, leading to corresponding symptoms. For example, metastasis of gastric cancer to the liver can cause abdominal pain and ascites due to hepatic metastatic tumors. Clinical manifestations caused by such metastatic tumors also include metastasis to retroperitoneal lymph nodes in the abdominal cavity, a common site of spread for gastric cancer. Patients may even show symptoms of intestinal obstruction, such as abdominal pain, bloating, nausea, vomiting, inability to pass stool, or even absence of flatus, which are indicators of intestinal obstruction. Consequently, patients might experience weight loss and deteriorate into a cachectic state, marked by poor nutrition and significant weight loss, which are characteristic symptoms of late-stage patients.

doctor image
home-news-image
Written by Liu Liang
Oncology
32sec home-news-image

Early manifestations of gastric cancer

The early signs of gastric cancer may include nausea, vomiting, or mild acid reflux, which are symptoms similar to those of gastritis, stomach ulcers, or duodenal ulcers. Therefore, initially, these patients may not take their condition seriously, assuming they might just have gastritis or peptic ulcers. These are some of the early manifestations of gastric cancer, and some patients may also experience discomfort and a feeling of fullness after eating.

doctor image
home-news-image
Written by Liu Liang
Oncology
51sec home-news-image

Mid-stage symptoms of gastric cancer

Symptoms of mid-stage gastric cancer can include nausea, vomiting, poor appetite, decreased food intake, and upper abdominal pain, as well as symptoms related to the digestive tract. Some patients may also experience black stool or even vomiting blood, which are symptoms of upper gastrointestinal bleeding. Additionally, there can be bloating and abdominal pain. If the tumor is located near the pylorus and causes pyloric obstruction, clinical symptoms will include vomiting, vomiting of overnight food, and resulting in gastric retention. This can lead to significant symptoms such as abdominal pain, bloating, acid reflux, and nausea.