How is malignant lymphoma treated?

Written by Peng Li Bo
Oncology
Updated on January 16, 2025
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The common treatments for malignant lymphoma currently include chemotherapy, targeted therapy, radiation therapy, and the use of immunosuppressants. There are also newer treatments such as cell reinfusion. The choice of treatment for malignant lymphoma definitely depends on the specific pathological type. Another factor is the stage of the lymphoma—it could be in stages one, two, three, or four, which definitely matters. The third factor is whether the lymphoma causes any symptoms or signs in the patient because some minor lymphomas may allow for observation and waiting, but many require active treatment.

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Written by Liu Liang
Oncology
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What is lymphoma?

Lymphoma refers to a type of malignant tumor that originates in the lymph nodes or extranodal tissues or organs. It is clinically categorized into two main types: Hodgkin's lymphoma and non-Hodgkin's lymphoma. Furthermore, it can be subdivided into many different pathological types. Among these, diffuse large B-cell lymphoma is the most common type in China, and there are dozens of different pathological types. The pathological type of the lymphoma determines its malignancy level, prognosis, chemotherapy regimen options, and treatment methods, all of which can vary significantly.

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Written by Liu Liang
Oncology
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Early symptoms of lymphoma

The early symptoms of lymphoma patients are primarily due to its predilection for lymph nodes, with the majority of cases initially presenting with swollen lymph nodes in the neck or collarbone area. These lymph nodes usually enlarge progressively without pain, which is the most common early clinical symptom. However, some specific types of lymphoma, such as nasal NKT lymphoma, present with localized symptoms like nasal congestion, nosebleeds, or a runny nose. There are also lymphomas originating in the stomach, part of the digestive tract, whose symptoms include upper abdominal pain, nausea, or vomiting. Furthermore, some lymphomas originate in the skin, manifesting as skin nodules. Therefore, depending on the site of occurrence, the symptoms can vary, but the enlargement of superficial lymph nodes remains the primary clinical manifestation in most cases.

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Written by Peng Li Bo
Oncology
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How is malignant lymphoma treated?

The common treatments for malignant lymphoma currently include chemotherapy, targeted therapy, radiation therapy, and the use of immunosuppressants. There are also newer treatments such as cell reinfusion. The choice of treatment for malignant lymphoma definitely depends on the specific pathological type. Another factor is the stage of the lymphoma—it could be in stages one, two, three, or four, which definitely matters. The third factor is whether the lymphoma causes any symptoms or signs in the patient because some minor lymphomas may allow for observation and waiting, but many require active treatment.

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Written by Peng Li Bo
Oncology
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Causes of Malignant Lymphoma

Currently, the causes of lymphoma are not clear. It may be related to genetic mutations, infections, pathogens, or other viruses. Additionally, exposure to radiation or chemical drugs, and its association with autoimmune diseases, are also relevant factors. Clinically, there are specific types of lymphoma, such as mucosa-associated lymphoma related to the stomach lining, which is notably associated with Helicobacter pylori infections. Another type is related to infection with the Epstein-Barr virus.

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Written by Wu Xia
Oncology
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How long can lymphoma last?

In clinical practice, lymphomas are classified into Hodgkin's lymphoma and non-Hodgkin's lymphoma. Non-Hodgkin's lymphoma is a relatively common type of tumor in China and has the highest incidence among lymphomas. However, it is further divided into dozens of subtypes, each with distinct clinical symptoms. Aggressive lymphomas can be cured, while indolent lymphomas can be managed with the tumor remaining. Thus, the question of how long one can live with lymphoma cannot be generalized; it depends on the type and stage of the disease, and many can be cured completely.