Early symptoms of lymphoma

Written by Liu Liang
Oncology
Updated on September 03, 2024
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The early symptoms of lymphoma patients are primarily due to its predilection for lymph nodes, with the majority of cases initially presenting with swollen lymph nodes in the neck or collarbone area. These lymph nodes usually enlarge progressively without pain, which is the most common early clinical symptom. However, some specific types of lymphoma, such as nasal NKT lymphoma, present with localized symptoms like nasal congestion, nosebleeds, or a runny nose. There are also lymphomas originating in the stomach, part of the digestive tract, whose symptoms include upper abdominal pain, nausea, or vomiting. Furthermore, some lymphomas originate in the skin, manifesting as skin nodules. Therefore, depending on the site of occurrence, the symptoms can vary, but the enlargement of superficial lymph nodes remains the primary clinical manifestation in most cases.

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Written by Liu Liang
Oncology
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Can lymphoma be cured?

Whether lymphoma can be cured depends on the specific pathological type of lymphoma, as there are dozens of subtypes, each with different prognoses and sensitivities to treatment. Additionally, the stage of lymphoma in patients also affects the prognosis. For example, patients with early-stage lymphoma can achieve a cure through radiotherapy and chemotherapy. However, for patients with advanced-stage lymphoma, treatment primarily involves chemotherapy, especially in cases of highly aggressive lymphoma, where it is difficult to achieve a complete cure. The goal of treatment in such cases is to alleviate pain and extend the patient's life.

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Written by Zhou Chen
Oncology
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What to check for malignant lymphoma?

The examination of lymphoma first requires routine blood tests and blood smears. When aggressive lymphoma invades the bone marrow, anemia, decreased white blood cells, and platelets may occur, and lymphoma cells can appear in peripheral blood; therefore, bone marrow smears and biopsies are necessary. Additionally, blood biochemistry is important, as an increase in lactate dehydrogenase is associated with tumor burden and is an indicator of poor prognosis. Furthermore, Hodgkin's lymphoma may involve the central nervous system, so patients with symptoms of central nervous system involvement need to undergo cerebrospinal fluid examination. The most important aspect of lymphoma is the histopathological examination. Based on the histopathological examination, the pathological staging is determined, and genetic rearrangement can also be performed.

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Written by Liu Liang
Oncology
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Early symptoms of lymphoma

The early symptoms of lymphoma patients are primarily due to its predilection for lymph nodes, with the majority of cases initially presenting with swollen lymph nodes in the neck or collarbone area. These lymph nodes usually enlarge progressively without pain, which is the most common early clinical symptom. However, some specific types of lymphoma, such as nasal NKT lymphoma, present with localized symptoms like nasal congestion, nosebleeds, or a runny nose. There are also lymphomas originating in the stomach, part of the digestive tract, whose symptoms include upper abdominal pain, nausea, or vomiting. Furthermore, some lymphomas originate in the skin, manifesting as skin nodules. Therefore, depending on the site of occurrence, the symptoms can vary, but the enlargement of superficial lymph nodes remains the primary clinical manifestation in most cases.

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Written by Liu Liang
Oncology
45sec home-news-image

The pattern of fever in lymphoma

Fever symptoms are quite common in patients with lymphoma, which we refer to as B symptoms. The pattern of their fevers is primarily low-grade, occurring more frequently in the afternoon or evening. Unlike ordinary bacterial infections, fevers in these patients do not respond well to anti-inflammatory drugs, but they do respond better to steroid treatment for reducing fever. However, if the lymphoma is not under control, their fever will repeatedly recur. Corresponding cooling treatments can reduce the temperature, but the fever will reoccur repeatedly. Only when the lymphoma and tumor are under control will the fever symptoms start to improve.

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Written by Zhou Zi Hua
Oncology
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Typical symptoms of lymphoma

Typical symptoms of lymphoma include night sweats, fever, and weight loss. This fever often occurs in the afternoon, characterized as a cyclical fever that lasts for several days with irregular patterns. There are fever-free intervals ranging from a few days to several weeks, almost a nonspecific symptom but not commonly seen. Fever, night sweats, and unexplained weight loss of more than 10% within six months, or even emaciation, are considered B symptoms and are associated with a poor prognosis. In addition, skin itching is also not uncommon in late-stage patients.