Lymphoma rash symptoms

Written by Peng Li Bo
Oncology
Updated on December 06, 2024
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The rash associated with lymphoma is not much different from common rashes; they are both characterized by red papules. However, lymphoma is not an isolated disease. For instance, in patients, one can feel lumps on the neck or upper clavicle area, but they may also exhibit systemic symptoms such as fever, night sweats, weight loss, fatigue, lack of appetite, anemia, chest pain, and other symptoms because it is a systemic disease. Thus, it may cause these systemic symptoms. The rash can also cause itching of the skin.

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Written by Liu Liang
Oncology
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What is lymphoma?

Lymphoma refers to a type of malignant tumor that originates in the lymph nodes or extranodal tissues or organs. It is clinically categorized into two main types: Hodgkin's lymphoma and non-Hodgkin's lymphoma. Furthermore, it can be subdivided into many different pathological types. Among these, diffuse large B-cell lymphoma is the most common type in China, and there are dozens of different pathological types. The pathological type of the lymphoma determines its malignancy level, prognosis, chemotherapy regimen options, and treatment methods, all of which can vary significantly.

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Written by Peng Li Bo
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Hodgkin's lymphoma symptoms and signs

Actually, whether it is Hodgkin's lymphoma or non-Hodgkin's lymphoma, the symptoms and signs are quite similar. In terms of symptoms, because lymphoma mainly occurs as a lesion in the lymph nodes, it is characterized by superficial, localized enlargement of the lymph nodes. Common locations include the neck, then the armpits, and the groin—areas where lymph nodes are more prevalent. It manifests as a local swelling; simply put, you might feel a lump or a tumor on your neck, which is the most common symptom. Additionally, there are other systemic symptoms including fever, weight loss, night sweats, and itchy skin, among others. As for the physical signs, it mainly refers to palpable superficial lymph node enlargement upon examination.

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The difference between lymphoma and lymphatic cancer

Cancer, commonly referred to as malignant tumors in everyday language, is generally known to the public simply as cancer—for example, lung cancer, liver cancer, colon cancer, etc. It specifically refers to malignant tumors that occur in epithelial tissue, which we call cancer. Lymphoma, on the other hand, refers to malignant tumors that occur in lymph nodes, or in extranodal organs or tissues, which we call lymphoma. There are also malignant tumors that occur in mesenchymal tissue, known as sarcomas. In fact, lymphoma is also a type of malignant tumor, so people commonly refer to it as lymphatic cancer. Therefore, lymphoma and lymphatic cancer are essentially the same disease, with lymphatic cancer specifically referring to lymphoma.

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Causes of Malignant Lymphoma

The causes of malignant lymphoma are the result of multiple factors. First, it is associated with infections by bacteria or viruses, such as the well-documented chronic infection with Helicobacter pylori, which is closely related to the occurrence of lymphoma associated with the gastric mucosa. Second, immunodeficiency conditions, like in AIDS patients or those who have been taking immunosuppressive drugs for a long period, have a higher likelihood of developing malignant lymphoma compared to the general population. Third, chemical or physical factors, such as environmental carcinogens and electromagnetic radiation, can also lead to malignant lymphoma. Other factors, such as long-term use of certain drugs like phenytoin or pseudoephedrine, and a genetic predisposition, can also be causes of malignant lymphoma.

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Written by Peng Li Bo
Oncology
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How is malignant lymphoma treated?

The common treatments for malignant lymphoma currently include chemotherapy, targeted therapy, radiation therapy, and the use of immunosuppressants. There are also newer treatments such as cell reinfusion. The choice of treatment for malignant lymphoma definitely depends on the specific pathological type. Another factor is the stage of the lymphoma—it could be in stages one, two, three, or four, which definitely matters. The third factor is whether the lymphoma causes any symptoms or signs in the patient because some minor lymphomas may allow for observation and waiting, but many require active treatment.