early symptoms of Hodgkin's lymphoma

Written by Liu Liang
Oncology
Updated on November 04, 2024
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Malignant lymphoma refers to a type of malignant tumor that originates in the lymph nodes or extranodal organs or tissues. Therefore, Hodgkin's lymphoma is a type of lymphoma. Its early symptoms mainly start with the enlargement of superficial lymph nodes throughout the body, with 90% of Hodgkin's lymphoma patients presenting with enlargement of superficial lymph nodes as an early symptom when they seek medical advice. The most common superficial lymph nodes are those above the collarbone and in the neck, but enlargement can also occur in the axillary and inguinal lymph nodes, which are also some of the more common early clinical manifestations seen in practice.

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How is Hodgkin's lymphoma treated?

The treatment of Hodgkin's lymphoma is based on various factors including the stage of the disease as well as the general condition of the patient, among other comprehensive considerations. For patients with early stage Hodgkin's lymphoma, commonly referred to as localized Hodgkin's lymphoma, the treatment principle is a combination of chemotherapy and radiotherapy. A rational comprehensive treatment can achieve a five-year survival rate of 80% to 90%. For advanced-stage patients, such as those with stage IV Hodgkin's lymphoma, the treatment primarily consists of systemic chemotherapy. Therefore, the choice of a specific treatment plan must also consider a variety of factors based on the patient's overall condition.

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Oncology
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Early symptoms of lymphoma

The early symptoms of lymphoma involve the painless enlargement of both superficial and deep lymph nodes, most commonly located in areas such as the neck, armpits, and groin. Of course, lymphoma also presents with systemic symptoms, such as fever, night sweats, weight loss, and skin itching. Since lymphoma commonly occurs in the neck, armpits, and groin, if it develops in other areas, such as the lungs or elsewhere, it may cause respiratory symptoms, including coughing, expectoration, and shortness of breath.

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Causes of Malignant Lymphoma

The causes of malignant lymphoma are the result of multiple factors. First, it is associated with infections by bacteria or viruses, such as the well-documented chronic infection with Helicobacter pylori, which is closely related to the occurrence of lymphoma associated with the gastric mucosa. Second, immunodeficiency conditions, like in AIDS patients or those who have been taking immunosuppressive drugs for a long period, have a higher likelihood of developing malignant lymphoma compared to the general population. Third, chemical or physical factors, such as environmental carcinogens and electromagnetic radiation, can also lead to malignant lymphoma. Other factors, such as long-term use of certain drugs like phenytoin or pseudoephedrine, and a genetic predisposition, can also be causes of malignant lymphoma.

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What department should lymphoma go to?

Lymphoma can be treated in the departments of hematology or oncology, where chemotherapy for lymphoma can be conducted by both. In our hospital, radiotherapy is performed in the oncology department, not by the hematology department, which only provides chemotherapy. If lymphoma has not been confirmed and there is only superficial lymph node enlargement clinically, then examinations such as ultrasound or PADCT suggest the possibility of lymphoma. In such cases, patients can visit the general surgery department for a lymph node biopsy to confirm the diagnosis. After confirmation, the patient can register in either the hematology or oncology department for further treatment.

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Lymphoma rash symptoms

The rash associated with lymphoma is not much different from common rashes; they are both characterized by red papules. However, lymphoma is not an isolated disease. For instance, in patients, one can feel lumps on the neck or upper clavicle area, but they may also exhibit systemic symptoms such as fever, night sweats, weight loss, fatigue, lack of appetite, anemia, chest pain, and other symptoms because it is a systemic disease. Thus, it may cause these systemic symptoms. The rash can also cause itching of the skin.