What tests are done for ovarian cancer screening?

Written by Liu Liang
Oncology
Updated on May 25, 2025
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In terms of ovarian cancer screening, we first start with a gynecological examination, followed by a pelvic ultrasound of the adnexa uteri in gynecology. For patients who have given birth, it is best to perform a transvaginal ultrasound of the adnexa uteri. Additionally, blood tests are performed to check the ovarian cancer tumor marker CA125, which is a tumor marker with relatively high specificity and sensitivity, especially for ovarian epithelial cancer. For such types of ovarian cancer, the CA125 level generally shows a significant increase. Therefore, during screening, this tumor marker can be checked in conjunction with a pelvic ultrasound to screen for the disease.

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Oncology
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What causes ovarian cancer?

The causes of ovarian cancer, and its mechanism of onset, are not yet very clear. Some risk factors that have been relatively well established in relation to the occurrence of ovarian cancer include early menarche, which means starting menstruation at an earlier age, late menopause, and not having a history of pregnancy; these conditions are some of the risk factors for ovarian cancer. Additionally, the occurrence of ovarian cancer is also somewhat related to familial or genetic factors.

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Can ovarian cancer be treated?

Ovarian cancer is certainly treatable. Its treatment methods include surgery, radiotherapy, and chemotherapy. For patients with early-stage ovarian cancer, the treatment is mainly radical surgery, followed by determining the need for additional adjuvant radiotherapy or chemotherapy based on specific pathological staging, the presence of high-risk factors for recurrence such as vascular tumor thrombus and neural invasion, and the situation of lymph node metastasis. For patients with advanced ovarian cancer, the treatment may involve debulking surgery and chemotherapy, with chemotherapy being the main treatment. Chemotherapy also needs to take into account the patient's general condition, along with local pelvic radiotherapy. These are the treatment methods for ovarian cancer, and the specific treatment plan should be selected based on staging and the patient's general condition, as well as the presence of other serious underlying diseases.

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Written by Liu Liang
Oncology
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How long can one live with ovarian cancer?

The lifespan of ovarian cancer patients depends on several factors including the specific stage of the cancer, the patient's sensitivity and response to treatment, and the overall health of the patient, leading to significant individual variability. The cancer is typically classified into stages from one to four, with stage one being the earliest and stage four being the most advanced. Generally, patients diagnosed at an earlier stage tend to have a better prognosis and a greater chance of survival compared to those with advanced ovarian cancer. Additionally, patients in advanced stages who respond well to treatments like chemotherapy typically have a better prognosis and longer survival times compared to those who are less responsive to such treatments. Hence, it is impossible to generalize as the individual differences are substantial.

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Written by Gong Chun
Oncology
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How is ovarian cancer treated?

Our treatment principle is that once an ovarian tumor is detected, surgical treatment should be performed. First and foremost, we need to confirm the diagnosis. Second, we should clarify the pathological staging of the ovarian cancer to guide the treatment. It's not a single approach; it's a comprehensive treatment plan. For example, if it is early stage and there are no surgical contraindications, we can proceed with surgical treatment. After the surgery, we can provide adjunctive chemotherapy. If surgery is not immediately feasible, we can also provide neoadjuvant therapy to reduce the stage before proceeding with ovarian cancer surgery. Moreover, there is now targeted therapy and immunotherapy for ovarian cancer, so it is a comprehensive treatment plan.

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Written by Yan Chun
Oncology
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What are the symptoms and early signs of ovarian cancer?

The symptoms and early signs of ovarian cancer mainly include the following aspects. Patients may experience persistent lower abdominal pain for no apparent reason, and some patients may experience radiating pain in the vulvar area, while others may show early clinical signs of abdominal bloating. The symptoms and early signs of ovarian cancer are not very numerous. Some patients may exhibit menstrual irregularities, such as increased or decreased menstruation, prolonged periods, or irregular vaginal bleeding. A few patients may experience abnormal vaginal discharge, which can be mixed with an unusual odor and a small amount of blood.