What tests are done for ovarian cancer screening?

Written by Liu Liang
Oncology
Updated on May 25, 2025
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In terms of ovarian cancer screening, we first start with a gynecological examination, followed by a pelvic ultrasound of the adnexa uteri in gynecology. For patients who have given birth, it is best to perform a transvaginal ultrasound of the adnexa uteri. Additionally, blood tests are performed to check the ovarian cancer tumor marker CA125, which is a tumor marker with relatively high specificity and sensitivity, especially for ovarian epithelial cancer. For such types of ovarian cancer, the CA125 level generally shows a significant increase. Therefore, during screening, this tumor marker can be checked in conjunction with a pelvic ultrasound to screen for the disease.

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Written by Liu Liang
Oncology
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Is ovarian cancer hereditary?

The onset of ovarian cancer may be somewhat related to family history or genetic factors. Therefore, patients with a family history of ovarian cancer may have a higher risk of developing the disease compared to the general population. However, this doesn't mean that a patient with ovarian cancer will definitely pass the condition to their offspring; it merely indicates a certain level of heredity. Furthermore, for those with a family history of breast cancer, colon cancer, and endometrial cancer, it is crucial for their descendants to undergo enhanced screenings for ovarian cancer and these diseases, as their risk of developing these conditions may be higher than that of the average person.

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Written by Liu Liang
Oncology
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Early Symptoms of Ovarian Cancer

Patients with ovarian cancer may have relatively hidden clinical symptoms in the early stages, possibly without any specific discomfort, or just mild lower abdominal bloating or pain. Symptoms tend to become more apparent only when the tumor progressively enlarges or when ascites occur, such as increased abdominal bloating and pain. Furthermore, during a physical examination, a solid or cystic-solid mass can be palpated in the pelvic area. Ascites can also lead to clinical symptoms such as nausea and vomiting. In the late stages, partial intestinal obstruction or symptoms related to pelvic compression may appear.

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Written by Liu Liang
Oncology
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Can ovarian cancer be detected by transvaginal ultrasound?

Ovarian cancer can generally be detected through a transvaginal ultrasound. During this procedure, we can find cystic or cystic-solid, or a solid mass in the ovaries. If a blood test for tumor markers shows a significant increase in CA125, especially in combination with a large amount of ascites, we must strongly suspect ovarian cancer. In such cases, patients should undergo a tumor biopsy. By taking a biopsy and confirming it pathologically, we can definitively diagnose ovarian cancer. Therefore, most ovarian cancer patients can indeed be detected through a transvaginal ultrasound.

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Written by Yan Chun
Oncology
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What are the early symptoms of ovarian cancer?

Ovarian cancer is one of the common gynecological malignancies in women. In the early stages, symptoms are not common and are not severe. The typical symptoms mainly manifest as pain and discomfort in the lower abdomen, and some patients may feel bloating in the lower abdomen. Some patients experience an increase in vaginal discharge, some have vaginal drainage or abnormal vaginal bleeding, and others may observe abnormal changes in their menstrual cycle, such as prolonged periods or increased menstrual flow, while some may experience reduced menstruation. Besides these, there are no other symptoms in early-stage ovarian cancer patients. As the disease progresses, the patient's abdominal pain and bloating will significantly worsen, indicating that the disease has advanced to the middle or late stages.

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Written by Gong Chun
Oncology
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What are the symptoms of ovarian cancer?

Ovarian cancer often does not present symptoms in its early stages and can be detected during gynecological examinations. Secondly, as the tumor grows, it can cause abdominal swelling and discomfort, and abdominal masses may be felt during examinations. Ascites may also develop. The severity of these symptoms depends on the size and location of the tumor, the nearby organs it invades, and the histological type of the tumor. Thirdly, if the tumor infiltrates or compresses surrounding tissues, it can also lead to abdominal pain, back pain, and pain in the lower extremities. If it compresses the pelvic veins, swelling in the lower limbs may occur. If the tumor is functional, it can produce symptoms related to excess estrogen or androgen. In its later stages, the condition may manifest as cachexia and severe anemia, among other signs of a severe illness state.