Is ovarian cancer hereditary?

Written by Liu Liang

Oncology

Updated on September 28, 2024

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The onset of ovarian cancer may be somewhat related to family history or genetic factors. Therefore, patients with a family history of ovarian cancer may have a higher risk of developing the disease compared to the general population. However, this doesn't mean that a patient with ovarian cancer will definitely pass the condition to their offspring; it merely indicates a certain level of heredity. Furthermore, for those with a family history of breast cancer, colon cancer, and endometrial cancer, it is crucial for their descendants to undergo enhanced screenings for ovarian cancer and these diseases, as their risk of developing these conditions may be higher than that of the average person.

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Written by Liu Liang

Oncology

1min

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Ovarian cancer pain symptoms

In the early stages of ovarian cancer, the symptoms can be quite hidden, and the patient may not feel any discomfort at all. However, as the tumor grows and ascites develops, the patient typically may experience abdominal bloating, or a palpable mass may be felt in the pelvic or lower abdominal area. At this point, symptoms such as pain in the lower abdomen may occur, especially when there is a substantial amount of ascites, leading to clinical symptoms like abdominal bloating and pain. In even more advanced stages of ovarian cancer, the tumor may invade surrounding pelvic organs, potentially causing partial intestinal obstruction or symptoms of pelvic compression. With conditions like intestinal obstruction, there will be significant abdominal pain, possibly accompanied by vomiting, especially after eating, which can exacerbate the symptoms.

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Written by Liu Liang

Oncology

1min 50sec

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ovarian cancer specific drug

Ovarian cancer does not have any specific cure-all treatment. Most ovarian cancers are epithelial ovarian cancers, and there is also ovarian cancer resulting from malignant germ cells, which is a rarer pathology type. For epithelial ovarian cancer, treatment methods include surgery, radiation therapy, chemotherapy, and some targeted therapies, mainly using Bevacizumab, which is a monoclonal antibody that inhibits angiogenesis, and is usually used in combination with chemotherapy drugs. For patients with advanced ovarian cancer, those who are resistant to chemotherapy, or those in poor general health unable to endure chemotherapy, palliative treatments like hormone treatment using progestogens are an option, along with immune therapy being available nowadays. Surgery is primarily for early-stage ovarian cancer patients, where curative surgical resection is possible, or for debulking surgery in patients with advanced ovarian cancer. Chemotherapy is frequently used as it is relatively effective for epithelial ovarian cancer, a type of cancer that is somewhat sensitive to such treatments. The drugs used mainly include taxane combined with platinum-based chemotherapy. For intravenous administration or intraperitoneal delivery—for the latter, mainly for ovarian cancers complicated by extensive ascites—, positioning an abdominal drainage tube and then infusing platinum-based chemotherapy drugs into the abdominal cavity are utilized.

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Written by Zhou Chen

Oncology

1min 12sec

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How is ovarian cancer diagnosed?

Early screening for ovarian cancer allows for about 20% of cases to be diagnosed in their early stages. Detection generally follows these procedures: 1. Routine gynecological health check-ups. 2. Visiting a hospital due to certain symptoms. 3. Ovarian cancer screening. Common methods include transvaginal ultrasound and serum CA125 testing. Additional tests include tumor marker CA125 and checks for AFP, CA19-9, and CEA. Ultrasonography (B-ultrasound) can preliminarily determine the tumor size, shape, solidity, location, and its relation to surrounding organs. CT scans and MRI can further clarify the tumor's nature and the extent of invasion into the abdominal and pelvic organs. If necessary, gastroscopy can be performed to rule out primary gastrointestinal tumors, and if economic conditions allow, a PADCT scan can also be conducted.

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Written by Liu Liang

Oncology

1min

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Symptoms of ovarian cancer

Ovarian cancer patients, especially those in the early stages, typically have inconspicuous symptoms, possibly without any noticeable discomfort. The disease is often discovered during gynecological examinations through the detection of abdominal masses. In advanced-stage patients, as the abdominal mass progressively enlarges, symptoms may include abdominal pain, lower abdominal bloating, and pelvic pressure symptoms due to compression of nearby organs. There may be partial intestinal obstruction, presenting as nausea, vomiting, abdominal pain, and inability to pass stool or gas. Another symptom is ascites, characterized by progressive enlargement and bloating of the abdomen. Ascites is a common clinical manifestation in ovarian cancer patients, and a significant portion of patients are diagnosed with ovarian cancer after presenting with ascites as the initial symptom.

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Written by Wu Xia

Oncology

53sec

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What to eat for difficulty in defecation due to ovarian cancer?

If the difficulty in defecation is due to ovarian cancer involving the rectum or other parts, we can apply anti-tumor treatments such as surgery and chemotherapy to control the condition and facilitate defecation. If the issue is caused by painkillers or the patient's inherent constipation, diet is crucial. The diet must include an adequate amount of fiber, more vegetables, and fruits. Avoid overly refined staple foods and include more whole grains. Drinking a glass of saltwater or honey water on an empty stomach in the morning, combined with appropriate waist and abdominal massage, can enhance the effect of facilitating bowel movements. If these measures are still ineffective, laxatives such as sodium docupate or lactulose may be used, along with some traditional Chinese medicines.