Will ovarian cancer increase AFP levels?

Written by Zhou Chen

Oncology

Updated on April 20, 2025

00:00

00:00

Ovarian cancer is one of the most common malignant tumors of the female reproductive organs, with an incidence rate second only to cervical cancer and endometrial cancer. Epithelial carcinoma is the most common type of malignant ovarian tumor, followed by malignant germ cell tumors, among which ovarian epithelial carcinoma has the highest mortality rate among all gynecological tumors. In cases of ovarian cancer, an increase in AFP is common, particularly in malignant germ cell tumors. The most common of these is the yolk sac tumor, which has a specific value, as its AFP levels are often significantly elevated.

Other Voices

home-news-image

Written by Gong Chun

Oncology

27sec

home-news-image

Early treatment methods for ovarian cancer

The treatment methods for early-stage ovarian cancer should first and foremost include a clear diagnosis and staging. If the staging indicates an early stage, then surgical treatment can be applied. There are many surgical options available, such as cytoreductive surgery, interval debulking surgery, second-look laparotomy, and direct tumor cell reduction surgery. After the surgery, adjuvant chemotherapy can be administered for treatment.

home-news-image

Written by Liu Liang

Oncology

51sec

home-news-image

How to control ascites from ovarian cancer?

In clinical settings, it is common for ovarian cancer to present with significant ascites. Some patients initially seek medical attention due to symptoms related to large volumes of ascites, and then ovarian cancer is diagnosed. Such cases are generally at a more advanced stage, and their treatment is predominantly chemotherapy. Ovarian cancer patients tend to be relatively sensitive to chemotherapy; only when chemotherapy controls the cancer cells can the ascites be managed. Of course, symptomatically, a peritoneal drainage tube can be placed to drain the ascites, and then local intraperitoneal chemotherapy drugs can be infused. This, combined with systemic intravenous chemotherapy, controls the ovarian cancer and manages the ascites.

home-news-image

Written by Wu Xia

Oncology

51sec

home-news-image

Can ovarian cancer be inherited?

Ovarian cancer, like most tumors, has genetic factors involved in its etiology, but it is not a genetic disease. Only five to ten percent of ovarian cancer patients have a genetic background. More than ninety percent of ovarian cancer cases are sporadic, meaning that if a mother has ovarian cancer, it does not directly inherit to her daughter. However, individuals with a family history of ovarian cancer have a significantly higher risk of developing the disease compared to the general population, especially those who carry mutations in the BRCA1 and BRCA2 genes. These gene mutations can be inherited from parents, so individuals carrying these mutations have a significantly higher risk of developing ovarian cancer than the healthy population.

home-news-image

Written by Yan Chun

Oncology

1min 10sec

home-news-image

Early symptoms of ovarian cancer

The early clinical symptoms of ovarian cancer primarily include the following aspects: 1. Discomfort and dull pain in the lower abdomen, with some patients experiencing a sensation of heaviness in the pelvis. Alongside this, patients may also experience poor appetite, nausea, belching, and a feeling of bloating in the stomach. 2. A sensation of abdominal fullness is a clinical manifestation that can appear early in ovarian cancer patients, often caused by cancerous ascites due to the disease. 3. In very few cases, early-stage ovarian cancer patients may feel a mass in the abdomen, typically in leaner patients. 4. Some early-stage patients may experience mild abdominal pain, which generally occurs intermittently and can resolve on its own without the need for medication. 5. Patients may exhibit menstrual irregularities and some endocrine symptoms, such as vaginal bleeding.

home-news-image

Written by Yan Chun

Oncology

58sec

home-news-image

What are the early symptoms of ovarian cancer?

Ovarian cancer is one of the common gynecological malignancies in women. In the early stages, symptoms are not common and are not severe. The typical symptoms mainly manifest as pain and discomfort in the lower abdomen, and some patients may feel bloating in the lower abdomen. Some patients experience an increase in vaginal discharge, some have vaginal drainage or abnormal vaginal bleeding, and others may observe abnormal changes in their menstrual cycle, such as prolonged periods or increased menstrual flow, while some may experience reduced menstruation. Besides these, there are no other symptoms in early-stage ovarian cancer patients. As the disease progresses, the patient's abdominal pain and bloating will significantly worsen, indicating that the disease has advanced to the middle or late stages.