Is rectal cancer without metastasis curable?

Written by Gong Chun
Oncology
Updated on March 08, 2025
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Can rectal cancer without metastases be treated successfully? If rectal cancer has not metastasized, its prognosis and outcome are relatively much better compared to cases where there are metastases and recurrences. If surgery is performed for rectal cancer and there is no recurrence or metastasis afterwards, then the five-year survival rate is naturally higher. However, if rectal cancer is initially treated surgically and cleaned thoroughly but then quickly recurs, with liver metastases, lung metastases, etc., then the five-year survival rate would be much lower. Therefore, if rectal cancer has not metastasized, the treatment and prognosis are much better. Thus, if there is no liver or lung metastasis in rectal cancer, the treatment is relatively easier.

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Written by Liu Liang
Oncology
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The difference between rectal cancer and colon cancer lies in the location of the cancer. Rectal cancer occurs in the rectum, which is the final part of the large intestine, while colon cancer occurs in other parts of the colon.

Rectal cancer and colon cancer are collectively referred to as colorectal cancer, named according to the different locations where the tumors occur. Rectal cancer occurs in the rectum. Colon cancer includes tumors in the transverse colon, descending colon, ascending colon, and sigmoid colon, and tumors in these areas are called colon cancer. Both are known as colorectal cancer, and they exhibit similar clinical manifestations, including rectal bleeding, abdominal pain, and changes in bowel habits, such as constipation, diarrhea, alternating constipation and diarrhea, and changes in stool shape, such as narrowing of the stool. They are merely named differently based on the location of the tumors and are collectively referred to as colorectal cancer.

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Written by Liu Liang
Oncology
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Rectal cancer stage III

Rectal cancer staging is based on the TNM system. "T" refers to the primary tumor, and its stage depends on which layer of the bowel wall the tumor has invaded. "N" is based on whether there are lymph node metastases and the number of lymph nodes involved. "M" indicates whether there are metastases to distant organs. Staging is determined according to the TNM situation, where Stage I is the earliest and Stage IV is the latest. Stage III indicates lymph node metastasis without distant organ metastases, such as to the liver or lungs. In such cases, irrespective of whether T is T1 to T4, if there is lymph node involvement without distant organ metastasis, it is staged as Stage III.

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Written by Yan Chun
Oncology
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What are the late-stage symptoms of rectal cancer?

The late-stage symptoms of rectal cancer patients in clinical practice mainly include the following types. The first type is abdominal symptoms caused locally by rectal cancer. For example: bloody stools, pass stools with mucous and pus, anal pain, bloating, abdominal pain, and other manifestations. The second category of symptoms is those from metastases in various locations. For example, bone metastases cause bone pain and limb movement disorders. Lung metastases cause chest tightness, shortness of breath after activity, chest pain, breathing difficulties, coughing and coughing up blood, etc. Brain metastases cause headaches, dizziness, and seizures. The third category of symptoms is mainly systemic symptoms caused by rectal cancer lesions, such as: weight loss, fatigue, and high fever.

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Written by Liu Liang
Oncology
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How long can one live after rectal cancer surgery?

The specific life expectancy after radical resection for rectal cancer varies among individuals and is dependent on various factors including the patient's general and physical condition, pathological staging post-surgery, and whether there are high-risk factors for recurrence such as lymph node metastasis, vascular tumor thrombus, and nerve invasion. The overall five-year survival rate post-surgery is approximately 50%. If the disease is confined to the submucosa and lacks high-risk factors such as vascular tumor thrombus, nerve invasion, or lymph node metastasis, the five-year survival rate after radical surgery can reach up to 90%. However, if post-surgery pathology reveals lymph node metastasis, vascular tumor thrombus, and nerve invasion, among other high-risk factors, the patient's five-year survival rate will decrease. Thus, survival rates are closely related to many factors.

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Written by Zhu Dan Hua
Gastroenterology
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Is a rectal polyp the same as rectal cancer?

Rectal polyps and rectal cancer are two different diseases, so it cannot be assumed that rectal polyps are rectal cancer. Rectal polyps are relatively common in clinical practice, especially among middle-aged and young patients, as they are often incidentally found during colonoscopy due to abnormal stools or abdominal discomfort. Generally, rectal polyps are small, ranging from a few millimeters to a maximum of one centimeter. Most rectal polyps are benign lesions, which can be managed with regular follow-ups or removed via endoscopy. Rectal cancer is generally considered a malignant tumor of the rectum, more commonly seen in older patients, who often exhibit alarming symptoms such as abdominal pain, rectal bleeding or abnormal stools, and in some cases, weight loss. Typically, malignant lesions in the rectum and tumor-like changes can be detected under colonoscopy. The main treatments include chemotherapy and surgical intervention.