Is hepatitis B cirrhosis serious?

Written by Zhang Jian Kang
Infectious Disease
Updated on September 15, 2024
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After infection with the hepatitis B virus, it may cause repeated inflammatory damage to the liver. If hepatitis B is not well-controlled, it can lead to the development of liver cirrhosis. The symptoms of liver cirrhosis mainly manifest as repeated fatigue, poor appetite, yellowing of the eyes, yellow urine, and discomfort in the upper abdomen after eating, etc. If the cirrhosis due to hepatitis B is in a compensated stage, such as liver cirrhosis suggested by ultrasonography and mild abnormalities in liver function, and the symptoms are not very severe, this type of compensatory cirrhosis, relatively speaking, has a decent prognosis. With standard antiviral treatment, many patients can maintain a state of liver cirrhosis. However, if treatment is not further pursued and damage progresses, leading to decompensated liver cirrhosis, or if ascites has already developed, or even gastrointestinal bleeding occurs, then its prognosis is relatively poor, and this situation is very serious.

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Written by Yang Chun Guang
Gastroenterology
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How to treat splenomegaly and liver cirrhosis?

Once liver cirrhosis is detected, accompanied by an enlarged spleen and hyperactive spleen function, this condition can be addressed through interventional methods to resolve issues of spleen enlargement and hyperfunction. This reduces the destruction of red blood cells, white blood cells, and platelets. The interventional approach primarily involves sterile necrosis and absorption of the spleen, thus resolving spleen issues. As for treating liver cirrhosis, it is primarily important to understand the causes of the cirrhosis. If the cirrhosis is caused by a virus, antiviral treatment is needed. There are corresponding antiviral medications for cirrhosis caused by hepatitis B and C. If the cirrhosis is caused by alcohol, it is essential to abstain from alcohol as part of the treatment. In addition, medications that combat liver cirrhosis should be used.

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Written by Wu Hai Wu
Gastroenterology
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Is early-stage cirrhosis easy to detect?

Early-stage liver cirrhosis can be detected through abdominal ultrasound examinations or blood tests, such as liver function tests, liver fibrosis quartet tests, or transient elastography of the liver. Once early-stage liver cirrhosis is diagnosed, further diagnostic tests are necessary to promptly determine the underlying causes of liver cirrhosis, allowing for causal and symptomatic treatment to begin as soon as possible. After the onset of liver cirrhosis, it is crucial to regularly complete abdominal ultrasound examinations and gastroscopy to check for the presence of complications such as ascites or bleeding from esophagogastric varices, among others.

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Written by Huang Gang
Gastroenterology
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What should I do about 7 episodes of gastrointestinal bleeding due to cirrhosis?

There are manifestations of cirrhosis, and it is accompanied by upper gastrointestinal bleeding, which occurs frequently. At this time, a gastroscopy should be conducted, in combination with an ultrasound examination of the liver, to determine whether portal hypertension is causing the bleeding. If the condition is serious, surgical treatment, such as disconnection or shunting, may be needed to relieve the pressure on the portal vein and mitigate the bleeding. Alternatively, vascular ligation can also be performed under gastroscopy to ligate the ruptured vessels, which can also stop the bleeding. Otherwise, long-term repeated heavy bleeding can easily lead to hemorrhagic anemia, and in severe cases, it can cause hemorrhagic shock, posing a life-threatening risk.

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Written by Li Qiang
Intensive Care Unit
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Which is more serious, liver failure or cirrhosis?

Liver failure refers to a functional impairment of the liver, which could be acute or chronic damage. For instance, it could be the end stage of chronic liver disease, or an acute condition such as hepatitis, or another acute liver lesion. Other common lesions may also cause a sudden abnormality in liver function, resulting in severe liver dysfunction. At this point, liver cirrhosis is a common cause of liver failure. For example, in the middle and late stages of liver cirrhosis, liver function is completely decompensated, meaning the liver can no longer maintain its basic normal functions, leading to liver failure. Therefore, liver failure is one of the major consequences of liver cirrhosis, but the two are distinct. Liver failure can also be caused by other reasons not related to cirrhosis. For example, acute ischemia in the liver, such as in shock patients, can lead to liver ischemia and subsequently liver failure. Liver cirrhosis is just one of the common causes thereof.

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Written by Wu Hai Wu
Gastroenterology
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In the early stages of cirrhosis, is there abdominal bloating and stomach pain?

Early-stage cirrhosis generally does not result in abdominal distension or stomach pain, and individuals in the early stages of liver cirrhosis might not exhibit any discomfort symptoms. However, if liver function reaches an advanced stage, complications like ascites associated with cirrhosis might occur, leading to abdominal distension. There might also be the occurrence of conditions like portal vein thrombosis, which can cause stomach pain, and possibly primary peritonitis, which can induce abdominal pain in patients. It is necessary to promptly identify the cause and adopt appropriate treatment measures. For example, if the stomach pain is caused by primary peritonitis, active anti-infection treatments should be applied.