How long does it take for fatty liver to progress to cirrhosis?

Written by Huang Gang
Gastroenterology
Updated on September 14, 2024
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How long does it take for fatty liver to progress to cirrhosis? Fatty liver is generally divided into mild, moderate, and severe fatty liver. If it is mild or moderate fatty liver, it can be reversed through proper exercise and diet control, meaning it can be cured. However, once it progresses to severe fatty liver, it can easily develop into cirrhosis, but the specific time required is about five years. Therefore, once we have fatty liver, it must be taken very seriously. With the improvement of living standards, most people are obese, which means that fatty liver is mostly caused by obesity. In terms of treatment, the focus is mainly on the cause, which is obesity. Patients need to follow a reasonable diet and actively exercise to lose weight. If successful in losing weight, fatty liver can be reversed, and we do not have to worry about fatty liver developing into cirrhosis.

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Can cirrhosis be detected by a CT scan?

Cirrhosis can be detected by a CT scan. Early-stage cirrhosis has no specific diagnostic value on CT, but middle to late-stage cirrhosis typically manifests as wavy changes in the liver capsule, enlarged liver lobes, and disproportionate size of liver lobes, with most changes involving an enlargement of the left lobe and caudate lobe and a relative shrinkage of the right lobe. Additionally, secondary manifestations of cirrhosis, such as portal hypertension, can cause enlargement of the spleen and varices in the lower esophagus and stomach fundus. When cirrhosis is detected, it is advisable to perform an enhanced CT scan to determine the potential for malignant transformation in liver regenerative nodules.

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Will cirrhosis continue to progress if there are no symptoms?

Cirrhosis may not have symptoms, yet it can still progress. There are various causes of cirrhosis, such as viral hepatitis, alcoholic hepatitis, autoimmune hepatitis, drug-induced hepatitis, and fatty liver disease, among others. If the underlying causes are not removed, cirrhosis can continue to progress even without symptoms. For example, in chronic hepatitis B, if no effective antiviral treatment is administered, the patient may progress to decompensated cirrhosis in the absence of symptoms, which in severe cases, can lead to the development of liver cancer. Therefore, once cirrhosis is diagnosed, it is crucial to actively identify the cause and adopt different treatments according to the specific cause, such as abstaining from alcohol if the cirrhosis is alcohol-related.

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Written by Li Qiang
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Is late-stage liver cirrhosis with liver failure easy to control?

In the late stages of cirrhosis, when the condition has progressed to liver failure, it becomes very difficult to manage. At this stage, due to liver failure, the first issue to arise is abnormal coagulation function, such as easy bleeding in patients. This will lead to severe hypoalbuminemia, causing swelling throughout the body. Additionally, bilirubin levels are very high, leading to various metabolic diseases, such as metabolic encephalopathy, which affects other organs as well. In the late stages of cirrhosis, there is also a large amount of ascites. At this time, portal hypertension is common, leading to complications such as gastric and esophageal varices rupture, bleeding, and hepatic encephalopathy, making the condition very difficult to control. If the cirrhosis is a benign lesion, at this time, adjusting liver function through methods such as artificial livers or plasma exchange can improve the condition to a manageable extent. It is critical to act quickly to perform a liver transplant, as there are no other effective treatments besides transplant, and the condition is very difficult to control.

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Does early-stage cirrhosis cause leg swelling?

Generally, in the early stages of cirrhosis, there is no swelling in the legs. However, if a patient with cirrhosis reaches the advanced stage and develops hypoalbuminemia, swelling in the feet can easily occur. At the same time, there is also the possibility of complications such as ascites, portal hypertensive gastropathy, and esophagogastric varices, among others. If swelling of the legs occurs in patients with cirrhosis, it indicates that the patient has entered the decompensated stage. At this point, it is necessary to go to the hospital as soon as possible to complete the relevant examinations to determine the cause of the cirrhosis, so that targeted treatment can be administered based on the cause as soon as possible.

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The difference between fatty liver and liver cirrhosis

Fatty liver is shown through ultrasound as having an increased and finely detailed echo in the liver, which is completely different from liver cirrhosis. Liver cirrhosis is generally caused by the progression of chronic hepatitis, commonly seen in hepatitis B-related cirrhosis, hepatitis C-related cirrhosis, and alcoholic cirrhosis. Cirrhosis resulting from drug-induced liver damage or from severe fatty liver is relatively rare in clinical practice. Therefore, we should not panic. Once diagnosed with fatty liver, it can be reversed through proper diet and reasonable exercise, and its progression to liver cirrhosis can be prevented. So, everyone, there is no need to rush or panic.