Early symptoms of cirrhosis

Written by Huang Ya Juan
Gastroenterology
Updated on September 05, 2024
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Liver cirrhosis is generally divided into compensated and decompensated stages: The compensated stage is actually an early stage of liver cirrhosis. During this stage, most patients do not show symptoms, or they may experience some mild symptoms such as abdominal discomfort, fatigue, loss of appetite, abdominal bloating, indigestion, diarrhea, etc. Decompensated stage: Early stages often present with fatigue and weakness, and later stages can include weight loss, loss of appetite, aversion to oily foods, abdominal bloating, diarrhea, fever, etc.; The liver is the only site of albumin synthesis, and during cirrhosis, reduced serum albumin can cause edema and ascites; the liver synthesizes most clotting factors, and cirrhosis can lead to coagulation disorders, clinically manifesting as gum bleeding, skin bruising, and nosebleeds; During cirrhosis, there can also be metabolic disorders of bilirubin and bile acids, leading to jaundice; Cirrhosis can also cause hormonal metabolic abnormalities, especially in patients with alcoholic cirrhosis, who may exhibit many characteristics of male dysfunction, including impotence, erectile dysfunction, testicular atrophy, loss of body hair and muscle mass, feminization, etc. Female patients may experience cessation or reduction of menstruation, excessive menstruation, infertility, etc.; Both male and female patients can develop osteoporosis, leading to spontaneous fractures.

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Written by Wu Hai Wu
Gastroenterology
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Why does cirrhosis cause increasing weight loss and what can be done about it?

The reason why patients with cirrhosis are becoming thinner might be due to the decreased protein synthesis function of the liver after cirrhosis, leading to progressively lesser protein in the body, which results in the patient becoming thinner. It could also be because cirrhosis leads to poor digestion and absorption in patients, thereby reducing their absorption capacity and causing them to lose weight. Under these circumstances, some medications can be used for treatment, such as the infusion of albumin to supplement plasma proteins in the body. It is also important to actively treat the underlying cause of cirrhosis. For example, in the case of alcoholic cirrhosis, active efforts to abstain from alcohol and rehabilitative treatment are necessary. If the cirrhosis is caused by chronic hepatitis B virus infection, antiviral treatment should be administered.

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Written by Wu Hai Wu
Gastroenterology
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Is the surface of the liver smooth in the early stages of cirrhosis?

In the early stages of cirrhosis, it is not necessarily the case that the liver surface is very smooth; in patients with early cirrhosis, the liver surface can be uneven. Patients in the early stages of cirrhosis also need serious attention. They should undergo regular follow-up examinations, and it is important to identify the cause of the early cirrhosis. Based on different causes, appropriate treatment measures should be taken. For example, if the early cirrhosis is caused by chronic hepatitis B virus, antiviral treatment should be initiated as soon as possible. If it is due to alcohol, leading to early alcoholic cirrhosis, then it is crucial to quit drinking actively, and liver-protective treatments are also needed.

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Written by Wu Hai Wu
Gastroenterology
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What is the difference between the symptoms of cholecystitis and the symptoms of cirrhosis?

The symptoms of cholecystitis differ significantly from those of cirrhosis. The symptoms of cholecystitis mainly manifest as pain in the upper right abdomen, along with chills and fever, while the symptoms of cirrhosis primarily include fatigue, poor appetite, and may also present with jaundice, abdominal distension, and swelling of the lower limbs. To determine whether a patient has cholecystitis or cirrhosis, it is recommended to visit the gastroenterology department of a standard hospital as soon as possible for a comprehensive examination. This should include abdominal imaging, liver function tests, complete blood count, among others, to further clarify the diagnosis and adopt corresponding treatment measures.

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Written by Li Qiang
Intensive Care Unit
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Is late-stage liver cirrhosis with liver failure easy to control?

In the late stages of cirrhosis, when the condition has progressed to liver failure, it becomes very difficult to manage. At this stage, due to liver failure, the first issue to arise is abnormal coagulation function, such as easy bleeding in patients. This will lead to severe hypoalbuminemia, causing swelling throughout the body. Additionally, bilirubin levels are very high, leading to various metabolic diseases, such as metabolic encephalopathy, which affects other organs as well. In the late stages of cirrhosis, there is also a large amount of ascites. At this time, portal hypertension is common, leading to complications such as gastric and esophageal varices rupture, bleeding, and hepatic encephalopathy, making the condition very difficult to control. If the cirrhosis is a benign lesion, at this time, adjusting liver function through methods such as artificial livers or plasma exchange can improve the condition to a manageable extent. It is critical to act quickly to perform a liver transplant, as there are no other effective treatments besides transplant, and the condition is very difficult to control.

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Written by Si Li Li
Gastroenterology
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Will early-stage cirrhosis cause lower back pain?

In the early stages of cirrhosis, there are generally no specific symptoms. Some patients may experience symptoms such as fatigue, nausea, vomiting, and aversion to oily foods. Typically, symptoms do not include lower back pain. However, if lower back pain occurs, it is necessary to consider and rule out diseases that frequently cause this symptom. Firstly, conditions such as lumbar muscle strain; secondly, issues like lumbar disc herniation or lumbar spine diseases; thirdly, kidney-related diseases, such as kidney stones, etc. Therefore, it is essential to first determine the cause of the lower back pain, or from the perspective of Traditional Chinese Medicine, whether the pain is related to kidney deficiency? Then, a differential diagnosis can be made, followed by treatment. This approach will ensure more effective therapeutic outcomes.