Early symptoms of cirrhosis

Written by Huang Ya Juan
Gastroenterology
Updated on September 05, 2024
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Liver cirrhosis is generally divided into compensated and decompensated stages: The compensated stage is actually an early stage of liver cirrhosis. During this stage, most patients do not show symptoms, or they may experience some mild symptoms such as abdominal discomfort, fatigue, loss of appetite, abdominal bloating, indigestion, diarrhea, etc. Decompensated stage: Early stages often present with fatigue and weakness, and later stages can include weight loss, loss of appetite, aversion to oily foods, abdominal bloating, diarrhea, fever, etc.; The liver is the only site of albumin synthesis, and during cirrhosis, reduced serum albumin can cause edema and ascites; the liver synthesizes most clotting factors, and cirrhosis can lead to coagulation disorders, clinically manifesting as gum bleeding, skin bruising, and nosebleeds; During cirrhosis, there can also be metabolic disorders of bilirubin and bile acids, leading to jaundice; Cirrhosis can also cause hormonal metabolic abnormalities, especially in patients with alcoholic cirrhosis, who may exhibit many characteristics of male dysfunction, including impotence, erectile dysfunction, testicular atrophy, loss of body hair and muscle mass, feminization, etc. Female patients may experience cessation or reduction of menstruation, excessive menstruation, infertility, etc.; Both male and female patients can develop osteoporosis, leading to spontaneous fractures.

Other Voices

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Written by Ye Xi Yong
Infectious Diseases
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Can cirrhosis caused by hepatitis B virus be cured?

Hepatitis B virus-induced cirrhosis was previously considered incurable, though its progression could be slowed. However, recent observations and studies have shown that a small fraction of patients with early-stage hepatitis B virus-induced cirrhosis can be cured. However, the proportion of these patients is extremely low. To draw an analogy, cirrhosis is like our houses. If the cement, steel bars, and brick structure are damaged, then the house is difficult to repair. Cirrhosis is akin to the structural damage of the house, making it hard to recover.

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Written by Wu Hai Wu
Gastroenterology
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Is stool black in the early stages of cirrhosis?

In the early stages of cirrhosis, it is generally not common to see black stools. Patients in the early stages of cirrhosis may not experience complications associated with the condition, such as portal hypertensive gastropathy and esophagogastric varices, nor would they likely suffer from peptic ulcers, etc. However, if patients with cirrhosis do not actively seek treatment or undergo regular check-ups, they could develop conditions like peptic ulcers and possibly esophagogastric varices that may rupture and bleed, leading to black stools. If black stools occur, it is important to promptly complete an endoscopic examination to confirm the diagnosis. Under endoscopy, hemostatic treatment should be performed. It is also crucial to actively rehydrate, suppress gastric acid secretion, and protect the gastric mucosa among other treatments.

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Written by Shen Jiang Chao
Radiology
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Can liver cirrhosis be detected by an ultrasound B-scan?

Liver cirrhosis can be diagnosed with an ultrasound. In the early stages of cirrhosis, there are no specific changes in the sonographic pattern visible on ultrasound. Typically, cirrhosis manifests as a decrease in liver volume, with imbalanced proportions of the liver lobes; both the left and right lobes may shrink, with compensatory hypertrophy observed in some cases in the left lobe. The liver capsule appears serrated, and the echoes from the liver area are coarser and stronger, with uneven distribution. It's possible to observe nodules with low or high echoes. The liver vessels vary in thickness, the hepatic veins may narrow, and the portal vein can widen. An enlarged portal vein can lead to symptoms like splenomegaly and ascites.

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Written by Si Li Li
Gastroenterology
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Will early-stage cirrhosis cause lower back pain?

In the early stages of cirrhosis, there are generally no specific symptoms. Some patients may experience symptoms such as fatigue, nausea, vomiting, and aversion to oily foods. Typically, symptoms do not include lower back pain. However, if lower back pain occurs, it is necessary to consider and rule out diseases that frequently cause this symptom. Firstly, conditions such as lumbar muscle strain; secondly, issues like lumbar disc herniation or lumbar spine diseases; thirdly, kidney-related diseases, such as kidney stones, etc. Therefore, it is essential to first determine the cause of the lower back pain, or from the perspective of Traditional Chinese Medicine, whether the pain is related to kidney deficiency? Then, a differential diagnosis can be made, followed by treatment. This approach will ensure more effective therapeutic outcomes.

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Written by Huang Gang
Gastroenterology
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The difference between fatty liver and liver cirrhosis

Fatty liver is shown through ultrasound as having an increased and finely detailed echo in the liver, which is completely different from liver cirrhosis. Liver cirrhosis is generally caused by the progression of chronic hepatitis, commonly seen in hepatitis B-related cirrhosis, hepatitis C-related cirrhosis, and alcoholic cirrhosis. Cirrhosis resulting from drug-induced liver damage or from severe fatty liver is relatively rare in clinical practice. Therefore, we should not panic. Once diagnosed with fatty liver, it can be reversed through proper diet and reasonable exercise, and its progression to liver cirrhosis can be prevented. So, everyone, there is no need to rush or panic.