Which is more serious, liver failure or cirrhosis?

Written by Li Qiang
Intensive Care Unit
Updated on November 18, 2024
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Liver failure refers to a functional impairment of the liver, which could be acute or chronic damage. For instance, it could be the end stage of chronic liver disease, or an acute condition such as hepatitis, or another acute liver lesion. Other common lesions may also cause a sudden abnormality in liver function, resulting in severe liver dysfunction. At this point, liver cirrhosis is a common cause of liver failure. For example, in the middle and late stages of liver cirrhosis, liver function is completely decompensated, meaning the liver can no longer maintain its basic normal functions, leading to liver failure. Therefore, liver failure is one of the major consequences of liver cirrhosis, but the two are distinct. Liver failure can also be caused by other reasons not related to cirrhosis. For example, acute ischemia in the liver, such as in shock patients, can lead to liver ischemia and subsequently liver failure. Liver cirrhosis is just one of the common causes thereof.

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Written by Zhang Jian Kang
Infectious Disease
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Symptoms of decompensated cirrhosis due to hepatitis B

Hepatitis B virus infection repeatedly leads to severe damage to the liver. If chronic hepatitis is not actively controlled, cirrhosis may occur. A symptom of decompensated cirrhosis mainly manifests as ascites, gastrointestinal bleeding, portal hypertension, and some people exhibit symptoms of hepatic encephalopathy. The presence of these complications indicates that the patient has reached the stage of decompensated cirrhosis. Patients in this stage often exhibit distinct jaundice, dark urine, abdominal distension after eating, and the presence of ascites with a positive shifting dullness. Additionally, some patients may experience vomiting blood, black stools, liver coma, and other related symptoms. Once these symptoms appear, it indicates that the prognosis for the patient is relatively poor.

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Written by Si Li Li
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Will early-stage cirrhosis cause lower back pain?

In the early stages of cirrhosis, there are generally no specific symptoms. Some patients may experience symptoms such as fatigue, nausea, vomiting, and aversion to oily foods. Typically, symptoms do not include lower back pain. However, if lower back pain occurs, it is necessary to consider and rule out diseases that frequently cause this symptom. Firstly, conditions such as lumbar muscle strain; secondly, issues like lumbar disc herniation or lumbar spine diseases; thirdly, kidney-related diseases, such as kidney stones, etc. Therefore, it is essential to first determine the cause of the lower back pain, or from the perspective of Traditional Chinese Medicine, whether the pain is related to kidney deficiency? Then, a differential diagnosis can be made, followed by treatment. This approach will ensure more effective therapeutic outcomes.

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Written by Huang Gang
Gastroenterology
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Can early cancerous changes in cirrhosis be cured?

If the patient has early-stage cirrhosis and develops cancerous changes, there are currently many treatment methods for liver cancer due to advanced science, so there is no need for immediate worry. The treatment for liver cancer can generally involve methods like microwave therapy, anhydrous alcohol injections, or surgery, including liver transplantation. One can choose the specific treatment method based on their individual medical condition. However, if suffering from hepatitis B or C-induced cirrhosis, it is recommended to take antiviral medications while treating liver cancer. This can help control the condition and delay its progression. It is also important to closely monitor the condition with frequent check-ups. If there is a possibility of recurrence of the liver condition, it is advisable to consider surgery or a liver transplant at an early stage.

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Written by Yang Chun Guang
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How to treat splenomegaly and liver cirrhosis?

Once liver cirrhosis is detected, accompanied by an enlarged spleen and hyperactive spleen function, this condition can be addressed through interventional methods to resolve issues of spleen enlargement and hyperfunction. This reduces the destruction of red blood cells, white blood cells, and platelets. The interventional approach primarily involves sterile necrosis and absorption of the spleen, thus resolving spleen issues. As for treating liver cirrhosis, it is primarily important to understand the causes of the cirrhosis. If the cirrhosis is caused by a virus, antiviral treatment is needed. There are corresponding antiviral medications for cirrhosis caused by hepatitis B and C. If the cirrhosis is caused by alcohol, it is essential to abstain from alcohol as part of the treatment. In addition, medications that combat liver cirrhosis should be used.

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Does early-stage cirrhosis exhibit spleen enlargement?

In the early stages of cirrhosis, spleen enlargement may occur, but generally, it is only a mild enlargement of the spleen. If the spleen shows significant enlargement, it generally indicates that the cirrhosis is no longer in the early stages. The main symptoms in the early stages of cirrhosis include an enlarged spleen, as well as denser liver parenchyma echoes and an uneven liver capsule surface. Once these early signs of cirrhosis appear, it is necessary to identify the cause as soon as possible and adopt cause-specific treatment. For example, if the cirrhosis is due to alcohol abuse, then it is necessary to abstain from alcohol. If it is due to chronic hepatitis B virus infection, antiviral treatments such as entecavir should be used. (Please use medication under the guidance of a doctor.)