Causes of neonatal jaundice

Written by Zhang Xian Hua
Pediatrics
Updated on April 09, 2025
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Neonatal jaundice is relatively common and its causes are usually related to the characteristics of neonatal bilirubin metabolism, which are mainly manifested in the following aspects: First, excessive production of bilirubin; second, poor ability of plasma albumin to bind bilirubin; third, poor ability of liver cells to process bilirubin; fourth, the enterohepatic circulation is more prevalent than in adults, thus making physiological jaundice more likely to occur. Furthermore, some children are affected by breastfeeding, with a portion of breastfed babies experiencing breast milk jaundice. Other factors include pathological reasons, such as viral infections common in hepatotropic viruses like cytomegalovirus, TORCH, etc.; jaundice can also occur following exposure to cold, which can lead to decreased resistance and bacterial infections; additionally, some children have jaundice due to genetic metabolic reasons.

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Written by Li Jiao Yan
Neonatology
1min 44sec home-news-image

Do newborns with jaundice need to be fed water?

Neonatal jaundice does not require the feeding of water. Neonatal jaundice is one of the common symptoms during the newborn period, especially in early newborns. It can be a symptom that appears during the normal development process of a newborn, or it can be an indication of certain diseases, with severe cases possibly leading to brain damage. Generally, about 80% of full-term infants can be observed to have jaundice with the naked eye. It is important for newborns with jaundice to differentiate between physiological jaundice and pathological jaundice. If it is physiological jaundice, no intervention is needed. However, if it is pathological jaundice, it is necessary to investigate the related causes and then manage it timely. Sometimes parents might hear that good bowel and urinary functions might lessen jaundice, and this is true. If the child has fewer bowel movements and less urine, and if feeding is insufficient, the jaundice can worsen. Therefore, in newborns, especially early newborns, it is crucial to ensure adequate feeding. Generally, if the baby is breastfed, the water content in breast milk is usually sufficient, so there is no need to add extra water. Additionally, if breast milk is not sufficient, ensuring the baby’s nutrition is important, and supplementing with some formula may be appropriate. It is generally recommended to exclusively breastfeed for the first six months without adding any other special foods or medicines, unless there are special medical indications. Thus, neonatal jaundice does not require the feeding of water.

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Written by Li Jiao Yan
Neonatology
1min 2sec home-news-image

Where to test for neonatal jaundice

Neonatal jaundice is one of the common symptoms during the newborn period. Generally, jaundice is monitored in hospitals after the baby is born. If the baby is discharged, jaundice still needs to be monitored. Normal physiological jaundice usually peaks around four to five days and subsides around ten days. If the baby's jaundice is higher than usual after discharge, more frequent monitoring is required. It is generally recommended that jaundice monitoring can be done at local community centers, maternal and child health hospitals, or people's hospitals with obstetrics and gynecology departments, where jaundice can typically be measured. The main test for jaundice is through transcutaneous bilirubin measurement. If the transcutaneous bilirubin measurement is high, it is necessary to confirm whether the bilirubin in the blood is high, which would require going to the hospital for a blood test and liver function test to determine the severity of the jaundice.

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Written by Yao Li Qin
Pediatrics
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Can neonatal jaundice be effectively treated?

Neonatal jaundice refers to the development of jaundice involving the whole body's skin and mucous membranes in newborns. For physiological jaundice in newborns, it can heal naturally. For pathological jaundice in newborns, with active treatment, including phototherapy, etiological treatment, and when necessary, administration of medications such as albumin and globulin, the more severe cases may require blood exchange treatment. Through the aforementioned treatments, neonatal jaundice can be effectively managed, so parents need not worry. If you notice jaundice in your child, actively take them to the hospital to cooperate with the doctor's treatment. In most cases, a satisfactory treatment outcome can be achieved. Parents can be reassured in this regard. (Please follow the guidance of a specialist for specific medications and do not medicate on your own.)

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Written by Li Jiao Yan
Neonatology
58sec home-news-image

Will newborn jaundice cause the ears to turn yellow?

Neonatal jaundice is one of the common symptoms in neonates, especially in early newborns. It can be a symptom of normal development in newborns, or it can be a manifestation of certain diseases. Jaundice is generally divided into physiological jaundice and pathological jaundice, with the main symptom being the yellowing of the skin and mucous membranes. Typically, jaundice starts from the face and then spreads to the trunk and limbs. If the degree of jaundice is relatively severe, yellowing will appear on the entire body, including the ears. Generally, if the baby is visibly yellow, it is advisable to monitor the jaundice. If the jaundice value is significantly high and confirmed to be high in the blood, it is considered pathological jaundice, and it is recommended to seek timely intervention and treatment.

doctor image
home-news-image
Written by Zhang Xian Hua
Pediatrics
58sec home-news-image

Causes of neonatal jaundice

Neonatal jaundice is relatively common and its causes are usually related to the characteristics of neonatal bilirubin metabolism, which are mainly manifested in the following aspects: First, excessive production of bilirubin; second, poor ability of plasma albumin to bind bilirubin; third, poor ability of liver cells to process bilirubin; fourth, the enterohepatic circulation is more prevalent than in adults, thus making physiological jaundice more likely to occur. Furthermore, some children are affected by breastfeeding, with a portion of breastfed babies experiencing breast milk jaundice. Other factors include pathological reasons, such as viral infections common in hepatotropic viruses like cytomegalovirus, TORCH, etc.; jaundice can also occur following exposure to cold, which can lead to decreased resistance and bacterial infections; additionally, some children have jaundice due to genetic metabolic reasons.