Where to test for neonatal jaundice

Written by Li Jiao Yan
Neonatology
Updated on April 04, 2025
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Neonatal jaundice is one of the common symptoms during the newborn period. Generally, jaundice is monitored in hospitals after the baby is born. If the baby is discharged, jaundice still needs to be monitored. Normal physiological jaundice usually peaks around four to five days and subsides around ten days. If the baby's jaundice is higher than usual after discharge, more frequent monitoring is required. It is generally recommended that jaundice monitoring can be done at local community centers, maternal and child health hospitals, or people's hospitals with obstetrics and gynecology departments, where jaundice can typically be measured. The main test for jaundice is through transcutaneous bilirubin measurement. If the transcutaneous bilirubin measurement is high, it is necessary to confirm whether the bilirubin in the blood is high, which would require going to the hospital for a blood test and liver function test to determine the severity of the jaundice.

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Written by Li Jiao Yan
Neonatology
1min 3sec home-news-image

Is a bilirubin level of 20 high for a newborn?

If a newborn's skin jaundice reaches a level of twenty, it is a warning sign that the jaundice is significantly elevated. It is advised to promptly go to the hospital for an examination. If the bilirubin levels in the blood are indeed that high, timely intervention and treatment are necessary. Normally, for physiological jaundice, the levels should not exceed fifteen after seventy-two hours in infants. Even during the peak period of four to five days, it should not surpass fifteen. If the jaundice noticeably increases within the first three days and exceeds twenty, the severity of the jaundice might be worse. The younger the newborn, especially with levels above twenty, the higher the risk of bilirubin entering the brain, potentially leading to bilirubin encephalopathy. Therefore, with jaundice reaching twenty, it is still recommended to promptly go to the hospital for intervention and treatment.

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Written by Li Jiao Yan
Neonatology
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How long does it take for neonatal jaundice to completely resolve?

Neonatal jaundice is the most common phenomenon in newborns. Generally, if it is physiological jaundice, for full-term infants, which are babies born after a full 37 weeks, the jaundice should resolve within two weeks. For preterm babies, those born before 37 weeks, the duration may be slightly longer, possibly lasting three to four weeks, but generally, it should clear up by four weeks. If it extends beyond these durations, like more than two weeks in full-term infants or more than four weeks in preterm infants, this is considered excessively prolonged jaundice. In such cases, a visit to the hospital is necessary. Doctors need to perform relevant checks to assess the severity of the jaundice and determine if there are any pathological factors involved. If pathological factors are present, timely intervention and treatment are required.

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Written by Li Jiao Yan
Neonatology
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Neonatal jaundice blue light therapy

Blue light therapy is one of the most common and effective treatments for neonatal jaundice, mainly targeting jaundice due to elevated indirect bilirubin. The principal mechanism of phototherapy involves transforming bilirubin into isomers, turning it from lipid-soluble to water-soluble, which can then be excreted through bile and urine without liver synthesis. Generally, the need for light therapy indicates a severe level of jaundice, but it is important to ascertain the type of bilirubin elevation before starting treatment. If the elevation involves conjugated bilirubin, light therapy will not be effective. Thus, if light therapy is necessary, it should be confirmed that the liver function issue involves elevated indirect bilirubin, in which case the effects of phototherapy are usually positive. The duration of treatment typically depends on the degree of jaundice and whether there are any complicating pathological factors. The method usually involves intermittent light exposure, generally spanning six to twelve hours. If the jaundice is more severe, continuous phototherapy lasting twenty-four to forty-eight hours might be required to reduce the bilirubin levels.

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Written by Yao Li Qin
Pediatrics
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What causes jaundice in newborns?

Neonatal jaundice is primarily due to the overproduction of bilirubin, which means a higher number of red blood cells are being destroyed, leading to an increased concentration of bilirubin in the blood. Additionally, there is a metabolic disorder of bilirubin in the child. The liver cells' ability to take up and bind bilirubin decreases, which can cause an increase in the concentration of unbound bilirubin in the serum, resulting in jaundice. This mainly occurs in cases of hypoxia, infection, and some congenital diseases, among others. Certain medications and reduced thyroid function can also present this symptom. The third issue is an impairment in the bile's ability to excrete bilirubin, which can occur when the child has neonatal hepatitis or congenital metabolic defects, leading to jaundice.

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Written by Li Jiao Yan
Neonatology
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How long should a newborn be exposed to blue light for jaundice?

If a baby's jaundice requires blue light therapy, it indicates that the jaundice is quite severe and is pathological. Blue light is one of the most effective treatments for jaundice, typically administered either continuously or intermittently. Continuous exposure is generally for a longer duration, such as for more severe conditions like hemolysis or serious infections, which cause a significant increase in jaundice levels, and typically requires 24 to 48 hours of continuous light treatment. If the jaundice is not very severe but still elevated, intermittent light treatment is usually adopted, lasting anywhere from 6 to 16 hours. Generally, if the jaundice does not rebound significantly after light treatment, there is no need for further light exposure. However, if the jaundice rebounds, additional treatment may be necessary. The duration of light therapy for jaundice depends on the baby's condition. If the cause of the jaundice is identified and treated, and the condition stabilizes, the duration of blue light therapy may be reduced. However, if the jaundice repeats or rebounds severely and is associated with significant pathological factors that are not fully controlled, then the treatment duration for jaundice will be longer.