Is atrophic gastritis C1 cancerous?

Written by Wu Hai Wu
Gastroenterology
Updated on May 31, 2025
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Atrophic gastritis C1 is not a cancerous change; it refers to closed atrophy, limited only to the pyloric antrum and not occurring in parts such as the gastric body or greater curvature. Patients with atrophic gastritis C1 should first be tested for the presence of Helicobacter pylori infection. If the Helicobacter pylori infection is positive, a standardized eradication of Helicobacter pylori should be conducted using a bismuth-containing quadruple therapy for two weeks. Additionally, patients can take Chinese patent medicines like Weifuchun and Monkey Mushroom tablets to repair and protect the gastric mucosa. Moreover, patients with atrophic gastritis C1 should regularly undergo follow-up gastroscopy. Note: Please follow medical advice regarding medication.

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Written by Jiang Guo Ming
Gastroenterology
1min 6sec home-news-image

What medicine should be taken for atrophic gastritis with erosion?

Chronic atrophic gastritis with erosion requires drug treatment based on the specific symptoms of the patient and whether there is a Helicobacter pylori infection. The infection rate of Helicobacter pylori is very high, often exceeding 50%, so it is also necessary to check for Helicobacter pylori infection in cases of chronic atrophic gastritis. If there is a Helicobacter pylori infection, antibacterial treatment is needed, typically employing a quadruple therapy. If there is no Helicobacter pylori infection, symptomatic treatment is generally used. Common treatments include protecting the gastric mucosa, suppressing gastric acid, and enhancing gastric motility, among others. Additionally, it is important to pay attention to daily diet and lifestyle habits, focusing on light and easy-to-digest foods, and avoiding raw, greasy, spicy, and irritating foods; quitting smoking and drinking can also be helpful. (Specific medication usage should be conducted under the guidance of a doctor.)

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Written by Wu Hai Wu
Gastroenterology
38sec home-news-image

Is the cancerous transformation of atrophic gastritis related to the duration of the disease?

The carcinogenesis of atrophic gastritis does not have a significant relationship with the duration of the disease. The main cause of atrophic gastritis is Helicobacter pylori infection, with autoimmune abnormalities and genetic factors also playing a significant role in atrophic gastritis. Sometimes, patients with a short duration of atrophic gastritis may also develop cancer, while those who have had the disease for many years may not necessarily develop cancer. Therefore, once atrophic gastritis is diagnosed, it is important to regularly re-examine with gastroscopy to rule out the possibility of early malignancy.

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Written by Si Li Li
Gastroenterology
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What should be done with chronic non-atrophic gastritis with erosion?

Chronic non-atrophic gastritis with erosion requires a biopsy of the eroded area during a gastroscopy for a pathological examination to determine the nature of the erosion, whether it is inflammatory, intestinal metaplasia, or atypical hyperplasia, etc. If the erosion is inflammatory, oral medication is needed for treatment, such as treatment against Helicobacter pylori, as well as acid suppression, stomach protection, promotion of gastric motility, and protection of the gastric mucosa. If intestinal metaplasia or moderate to severe atypical hyperplasia is present, endoscopic mucosal resection is recommended. This is because moderate to severe intestinal metaplasia or atypical hyperplasia has a certain rate of malignancy, and endoscopic mucosal resection is necessary for thorough treatment, as oral medication alone cannot completely cure this lesion.

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Written by Li Ying
Gastroenterology
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Can chronic atrophic gastritis be cured?

Chronic atrophic gastritis is primarily a chronic digestive system disease caused by atypical hyperplasia. It is mainly characterized by upper abdominal dull pain, bloating, loss of appetite, weight loss, anemia, etc., and lacks specificity. It is a disease caused by multiple pathogenic factors and is a precancerous lesion. There are many causes, including Helicobacter pylori infection and dietary factors, among others. Moreover, treatment for atrophic gastritis can be targeted based on the specific condition, clinical symptoms, and auxiliary examinations.

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Written by Wu Hai Wu
Gastroenterology
53sec home-news-image

Is atrophic gastritis C1 cancerous?

Atrophic gastritis C1 is not a cancerous change; it refers to closed atrophy, limited only to the pyloric antrum and not occurring in parts such as the gastric body or greater curvature. Patients with atrophic gastritis C1 should first be tested for the presence of Helicobacter pylori infection. If the Helicobacter pylori infection is positive, a standardized eradication of Helicobacter pylori should be conducted using a bismuth-containing quadruple therapy for two weeks. Additionally, patients can take Chinese patent medicines like Weifuchun and Monkey Mushroom tablets to repair and protect the gastric mucosa. Moreover, patients with atrophic gastritis C1 should regularly undergo follow-up gastroscopy. Note: Please follow medical advice regarding medication.