Is the cancerous transformation of atrophic gastritis related to the duration of the disease?

Written by Wu Hai Wu

Gastroenterology

Updated on February 19, 2025

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The carcinogenesis of atrophic gastritis does not have a significant relationship with the duration of the disease. The main cause of atrophic gastritis is Helicobacter pylori infection, with autoimmune abnormalities and genetic factors also playing a significant role in atrophic gastritis. Sometimes, patients with a short duration of atrophic gastritis may also develop cancer, while those who have had the disease for many years may not necessarily develop cancer. Therefore, once atrophic gastritis is diagnosed, it is important to regularly re-examine with gastroscopy to rule out the possibility of early malignancy.

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Written by Wu Hai Wu

Gastroenterology

48sec

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Can people with atrophic gastritis drink honey water?

Patients with atrophic gastritis can drink honey water. Patients with atrophic gastritis need to be careful with their diet by avoiding spicy, irritating foods, as well as overly sour, overly spicy, overly salty foods, and coarse foods. For patients with atrophic gastritis, it is important to eat regularly and in moderate amounts, opting for smaller, more frequent meals, and avoiding binge eating. Since honey water does not fall into the above categories of foods and is not considered spicy, patients with atrophic gastritis can drink honey water. However, it is also important to avoid drinking too much at once; drinking a moderate amount is fine.

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Written by Jiang Guo Ming

Gastroenterology

1min 6sec

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What medicine should be taken for atrophic gastritis with erosion?

Chronic atrophic gastritis with erosion requires drug treatment based on the specific symptoms of the patient and whether there is a Helicobacter pylori infection. The infection rate of Helicobacter pylori is very high, often exceeding 50%, so it is also necessary to check for Helicobacter pylori infection in cases of chronic atrophic gastritis. If there is a Helicobacter pylori infection, antibacterial treatment is needed, typically employing a quadruple therapy. If there is no Helicobacter pylori infection, symptomatic treatment is generally used. Common treatments include protecting the gastric mucosa, suppressing gastric acid, and enhancing gastric motility, among others. Additionally, it is important to pay attention to daily diet and lifestyle habits, focusing on light and easy-to-digest foods, and avoiding raw, greasy, spicy, and irritating foods; quitting smoking and drinking can also be helpful. (Specific medication usage should be conducted under the guidance of a doctor.)

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Written by Wu Hai Wu

Gastroenterology

49sec

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What is the cause of recurrent atrophic gastritis?

Recurrent atrophic gastritis is likely caused by Helicobacter pylori infection. When atrophic gastritis recurs, a Carbon-13 urea breath test or Carbon-14 urea breath test should be conducted to detect whether there is an infection of Helicobacter pylori. If the test is positive, a two-week quadruple therapy containing a bismuth agent should be used to eradicate Helicobacter pylori. Consider using a proton pump inhibitor, such as omeprazole or lansoprazole, combined with two of the antibiotics amoxicillin, clarithromycin, metronidazole, and furazolidone, as well as bismuth citrate, to form the quadruple therapy. (Please use medication under the guidance of a doctor.)

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Written by Si Li Li

Gastroenterology

1min 9sec

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Is atrophic gastritis of the gastric antrum serious?

Atrophic gastritis is a chronic gastric disease characterized by repeated damage to the gastric mucosal epithelium, leading to the atrophy of the intrinsic glands, with or without intestinal metaplasia or pseudopyloric gland metaplasia. The main cause of this disease is infection by Helicobacter pylori. Symptoms primarily include upper abdominal distension, belching, acid reflux, early satiety, nausea, etc. Some patients may experience symptoms such as weight loss, fatigue, memory loss, anxiety, and depression. The main treatment involves eradicating Helicobacter pylori, suppressing acid production, and using gastric mucosal protectants and prokinetic agents. The majority of patients have Helicobacter pylori-related gastritis, which after chronic inflammation (chronic non-atrophic gastritis) can lead to atrophic gastritis, followed by intestinal metaplasia or dysplasia, and eventually may progress to gastric cancer.

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Written by Feng Ying Shuai

Traditional Chinese Medicine

1min 7sec

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Where to apply moxibustion for atrophic gastritis?

For some symptoms of atrophic gastritis, moxibustion can be applied, such as on the Zhongwan acupoint located on the Ren meridian, as well as the Xiawan and Liangqiu acupoints. Moxibustion can also be done on the Zusanli acupoint along the stomach meridian, as well as on Neiguan and Gongsun acupoints, which are intersections of the eight meridians and can regulate atrophic gastritis. However, there is a particular method to follow during moxibustion; generally, acupoints on the upper body are treated first, followed by those on the lower body. For instance, start with the acupoints on the abdomen such as Zhongwan, Xiawan, and Liangqiu, followed by Zusanli, and then Gongsun. During moxibustion, the amount of moxa used should increase gradually, and the duration of treatment should extend from short to longer periods, indicating that the treatment period for atrophic gastritis might be longer.