Is the cancerous transformation of atrophic gastritis related to the duration of the disease?

Written by Wu Hai Wu
Gastroenterology
Updated on February 19, 2025
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The carcinogenesis of atrophic gastritis does not have a significant relationship with the duration of the disease. The main cause of atrophic gastritis is Helicobacter pylori infection, with autoimmune abnormalities and genetic factors also playing a significant role in atrophic gastritis. Sometimes, patients with a short duration of atrophic gastritis may also develop cancer, while those who have had the disease for many years may not necessarily develop cancer. Therefore, once atrophic gastritis is diagnosed, it is important to regularly re-examine with gastroscopy to rule out the possibility of early malignancy.

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Written by Jiang Guo Ming
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Atrophic gastritis with intestinal metaplasia what medicine to take

Chronic atrophic gastritis with intestinal metaplasia often arises from untreated chronic superficial gastritis, primarily due to Helicobacter pylori infection. Therefore, it is essential to first check for Helicobacter pylori infection. If an infection is present, quadruple therapy is generally used to eradicate the bacteria, which may improve the atrophy. If there is no Helicobacter pylori infection, treatment mainly involves protecting the gastric mucosa. While there are no specific Western medicines for this, traditional Chinese medicine and a differential diagnosis approach often yield good results. Regular follow-ups are also important. (Specific medications should be used under the guidance of a doctor.)

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Written by Wu Peng
Gastroenterology
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Chronic atrophic gastritis is what kind of condition?

Chronic atrophic gastritis is a digestive system disease characterized by atrophy of the intrinsic gastric glands. It is commonly seen in middle-aged and elderly people. Clinically, it mainly manifests as loss of appetite, nausea, belching, heartburn, and continuous or intermittent bloating and dull pain in the upper abdomen. A minority of patients may experience upper gastrointestinal bleeding, weight loss, anemia, and malnutrition, with incidence rates increasing significantly with age. Chronic atrophic gastritis can be divided into autoimmune gastritis and multifocal atrophic gastritis, also referred to as Type A gastritis and Type B gastritis, respectively. Gastric mucosal biopsy is a reliable method for its diagnosis.

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Written by Si Li Li
Gastroenterology
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Can atrophic gastritis with HP positive lead to cancer?

Chronic atrophic gastritis has a certain risk of cancerous transformation. For patients with chronic atrophic gastritis, the first step in treatment is to administer anti-Helicobacter pylori therapy, which includes a proton pump inhibitor, two types of antibiotics, and a bismuth agent, with a treatment duration of 14 days. Additionally, treatments to suppress stomach acid, protect the stomach lining, promote gastric motility, and repair the stomach mucosa are necessary. Treatment methods also involve traditional Chinese medicine (TCM) diagnoses and oral administration of Chinese herbal medicine. External TCM treatments, such as thunder-fire moxibustion and moxibustion on the Zhongwan acupoint, or the acupoints of spleen-shu and stomach-shu on the back, which strengthen the spleen and benefit qi to nourish the stomach, can also play a significant role in treating this disease.

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Written by Si Li Li
Gastroenterology
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Non-atrophic gastritis with focal erosion treatment

Non-atrophic gastritis with erosive lesions, primarily diagnosed through gastroscopic examination that revealed erosive and other changes in the gastric mucosa. If erosion is detected, doctors generally perform a biopsy under gastroscopy to ascertain the nature of the erosion. If the erosion is inflammatory, it can be treated with oral medications, including acid-suppressing and stomach-protective drugs, promoting gastric motility, and protecting the gastric mucosa. If the erosion involves intestinal metaplasia or atypical hyperplasia, it requires endoscopic APC treatment or endoscopic submucosal dissection (ESD) to eliminate the erosive areas, thereby addressing the erosion fundamentally. Additionally, attention should be paid to a light and easily digestible diet.

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Written by Wu Hai Wu
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Can people with atrophic gastritis drink honey water?

Patients with atrophic gastritis can drink honey water. Patients with atrophic gastritis need to be careful with their diet by avoiding spicy, irritating foods, as well as overly sour, overly spicy, overly salty foods, and coarse foods. For patients with atrophic gastritis, it is important to eat regularly and in moderate amounts, opting for smaller, more frequent meals, and avoiding binge eating. Since honey water does not fall into the above categories of foods and is not considered spicy, patients with atrophic gastritis can drink honey water. However, it is also important to avoid drinking too much at once; drinking a moderate amount is fine.