What should be done with chronic non-atrophic gastritis with erosion?

Written by Si Li Li
Gastroenterology
Updated on February 19, 2025
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Chronic non-atrophic gastritis with erosion requires a biopsy of the eroded area during a gastroscopy for a pathological examination to determine the nature of the erosion, whether it is inflammatory, intestinal metaplasia, or atypical hyperplasia, etc. If the erosion is inflammatory, oral medication is needed for treatment, such as treatment against Helicobacter pylori, as well as acid suppression, stomach protection, promotion of gastric motility, and protection of the gastric mucosa. If intestinal metaplasia or moderate to severe atypical hyperplasia is present, endoscopic mucosal resection is recommended. This is because moderate to severe intestinal metaplasia or atypical hyperplasia has a certain rate of malignancy, and endoscopic mucosal resection is necessary for thorough treatment, as oral medication alone cannot completely cure this lesion.

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Is nausea normal for atrophic gastritis?

Nausea is one of the common symptoms of gastrointestinal diseases, whether it is chronic superficial gastritis or atrophic gastritis. The occurrence of nausea usually indicates insufficient gastric motility. This condition is not considered normal, and targeted treatment is usually required depending on whether there is an infection with Helicobacter pylori. If there is an infection with Helicobacter pylori, it is first necessary to eradicate Helicobacter pylori. This generally involves quadruple therapy to eliminate the bacteria, accompanied by prokinetic agents, such as mosapride citrate. If there is no Helicobacter pylori infection, symptomatic treatment may suffice. For example, protecting the gastric mucosa and enhancing gastric motility, while also paying attention to daily dietary and lifestyle habits. (Note: The use of medications should be conducted under the guidance of a professional doctor.)

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Will atrophic gastritis and esophagitis cause significant weight loss?

Patients with atrophic gastritis and esophagitis may experience weight loss, as those with atrophic gastritis can have upper abdominal pain, distension pain, and burning pain, accompanied by a feeling of bloating and belching. Severe cases can lead to anemia and weight loss. The main cause of atrophic gastritis is infection by Helicobacter pylori. Of course, immune factors and dietary habits also play significant roles in the development of atrophic gastritis. Once atrophic gastritis is definitively diagnosed, it is crucial to actively eradicate Helicobacter pylori, as well as to quit smoking and drinking, and avoid using medications and consuming foods that may damage the gastric mucosa.

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What is the cause of recurrent atrophic gastritis?

Recurrent atrophic gastritis is likely caused by Helicobacter pylori infection. When atrophic gastritis recurs, a Carbon-13 urea breath test or Carbon-14 urea breath test should be conducted to detect whether there is an infection of Helicobacter pylori. If the test is positive, a two-week quadruple therapy containing a bismuth agent should be used to eradicate Helicobacter pylori. Consider using a proton pump inhibitor, such as omeprazole or lansoprazole, combined with two of the antibiotics amoxicillin, clarithromycin, metronidazole, and furazolidone, as well as bismuth citrate, to form the quadruple therapy. (Please use medication under the guidance of a doctor.)

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Written by Si Li Li
Gastroenterology
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Is chronic non-atrophic gastritis with erosion serious?

Common symptoms of chronic non-atrophic gastritis with erosion include upper abdominal bloating, belching, acid reflux, nausea, vomiting, poor appetite, indigestion, heartburn, etc. A gastroscopy can reveal symptoms like hyperemia, edema, and erosion on the gastric mucosa to diagnose chronic non-atrophic gastritis with erosion. It is also recommended to perform a Carbon-14 breath test to determine if there is an infection of Helicobacter pylori. If the infection is positive, a 14-day treatment for Helicobacter pylori is required, using a regimen of a proton pump inhibitor, two antibiotics, and a bismuth agent, with the course lasting 14 days. Additionally, treatment for chronic non-atrophic gastritis with erosion should include acid suppression, gastric protection, promoting gastric motility, and protecting the gastric mucosa, which typically requires about six weeks. With the above treatments, the disease can be cured.

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Is non-atrophic gastritis serious?

Chronic non-atrophic gastritis, which is commonly referred to as chronic superficial gastritis, is considered one of the milder upper gastrointestinal diseases. Endoscopic examinations usually show localized mucosal congestion and edema, which are not severe. The main cause is likely due to Helicobacter pylori infection, which can be effectively treated with antibacterial therapy. Other factors, such as exposure to cold or inappropriate dietary habits, as well as smoking and alcohol consumption, can also lead to this condition. Therefore, it is essential to pay attention to one’s dietary and living habits and try to avoid spicy and greasy foods and alcoholic beverages to prevent major issues.