What should be done with chronic non-atrophic gastritis with erosion?

Written by Si Li Li
Gastroenterology
Updated on February 19, 2025
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Chronic non-atrophic gastritis with erosion requires a biopsy of the eroded area during a gastroscopy for a pathological examination to determine the nature of the erosion, whether it is inflammatory, intestinal metaplasia, or atypical hyperplasia, etc. If the erosion is inflammatory, oral medication is needed for treatment, such as treatment against Helicobacter pylori, as well as acid suppression, stomach protection, promotion of gastric motility, and protection of the gastric mucosa. If intestinal metaplasia or moderate to severe atypical hyperplasia is present, endoscopic mucosal resection is recommended. This is because moderate to severe intestinal metaplasia or atypical hyperplasia has a certain rate of malignancy, and endoscopic mucosal resection is necessary for thorough treatment, as oral medication alone cannot completely cure this lesion.

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What to do about the pain from atrophic gastritis?

Atrophic gastritis is a condition where the mucous membrane of the stomach atrophies, associated with poor neural nutrition and excessive gastric acid secretion, leading to a reduction in the barrier function of the gastric mucosa. To first alleviate pain, proton pump inhibitors can be used to reduce the secretion of gastric acid, and at the same time, gastric mucosal protectants should be used. If there is an infection with Helicobacter pylori, active use of triple or quadruple therapy should be employed to eradicate Helicobacter pylori. It is important to adjust one's diet, eat regularly, and avoid overeating. Greasy and spicy foods should be consumed less, and more bland, soft, and easily digestible foods should be eaten. (Please use medication under the guidance of a doctor.)

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Chronic atrophic gastritis is what kind of condition?

Chronic atrophic gastritis is a digestive system disease characterized by atrophy of the intrinsic gastric glands. It is commonly seen in middle-aged and elderly people. Clinically, it mainly manifests as loss of appetite, nausea, belching, heartburn, and continuous or intermittent bloating and dull pain in the upper abdomen. A minority of patients may experience upper gastrointestinal bleeding, weight loss, anemia, and malnutrition, with incidence rates increasing significantly with age. Chronic atrophic gastritis can be divided into autoimmune gastritis and multifocal atrophic gastritis, also referred to as Type A gastritis and Type B gastritis, respectively. Gastric mucosal biopsy is a reliable method for its diagnosis.

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"Mild active phase of atrophic gastritis"

Mild active phase of atrophic gastritis refers to the period when gastritis is occurring, typically caused by improper diet. This might be due to overeating or consuming greasy, spicy, and irritating foods, leading to exacerbation of the condition. Clinical manifestations include stomach pain, nausea, vomiting, and decreased appetite, which are inevitably linked to daily life habits. Furthermore, mental stress, excessive pressure, staying up late, and overfatigue can also have an impact.

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Symptoms and Treatment of Atrophic Gastritis

Common symptoms of chronic atrophic gastritis include upper abdominal distension, belching, acid reflux, nausea, vomiting, postprandial fullness, heartburn, and indigestion. Gastroscopy can reveal atrophy of the gastric glands in the mucosa, and a definitive diagnosis of chronic atrophic gastritis can be made through biopsy and histopathological examination. In terms of treatment, the first step involves eradicating Helicobacter pylori, using a regimen that includes a proton pump inhibitor, two antibiotics, and a bismuth agent, over a 14-day treatment period. Additionally, treatments aimed at acid suppression, gastric motility enhancement, and gastric mucosal protection are also necessary. Traditional Chinese medicine can also be effective in treating atrophic gastritis. A combined approach utilizing both Western and Chinese medicine can yield better outcomes for the treatment of atrophic gastritis.

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What should be done with chronic non-atrophic gastritis with erosion?

Chronic non-atrophic gastritis with erosion requires a biopsy of the eroded area during a gastroscopy for a pathological examination to determine the nature of the erosion, whether it is inflammatory, intestinal metaplasia, or atypical hyperplasia, etc. If the erosion is inflammatory, oral medication is needed for treatment, such as treatment against Helicobacter pylori, as well as acid suppression, stomach protection, promotion of gastric motility, and protection of the gastric mucosa. If intestinal metaplasia or moderate to severe atypical hyperplasia is present, endoscopic mucosal resection is recommended. This is because moderate to severe intestinal metaplasia or atypical hyperplasia has a certain rate of malignancy, and endoscopic mucosal resection is necessary for thorough treatment, as oral medication alone cannot completely cure this lesion.