Early Symptoms and Warning Signs of Liver Cancer

Written by Yan Chun
Oncology
Updated on May 28, 2025
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The early symptoms of liver cancer primarily manifest as localized gastrointestinal symptoms. Patients develop an aversion to greasy foods and experience a decrease in appetite. Some may feel bloating and pain in the abdomen, nausea, and distention after eating, and even pain and bloating as early symptoms. Patients become reluctant to be active, and some liver cancer patients may not exhibit many symptoms in the early stages. The precursors of liver cancer mainly present as unexplained fatigue or generalized weakness. If individuals with a family history of liver cancer experience unexplained anorexia, fatigue, and lethargy, the possibility of liver cancer should be considered.

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Is primary liver cancer contagious?

Primary liver cancer refers to malignant tumors that occur in the liver and are not metastasized from other parts of the body. Such liver cancer itself is not contagious. However, if liver cancer patients have other infectious diseases, transmission may be possible. Most primary liver cancers are related to liver cirrhosis following hepatitis, with hepatitis B being the most common. If accompanied by hepatitis B, it can be contagious, but it usually doesn't spread through regular daily contact. The main transmission routes for hepatitis B are through blood, mother-to-child transmission, and sexual transmission. This means that as long as the patient's blood does not injure someone else, contagion is generally unlikely, so there is no need for excessive worry.

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How to effectively treat advanced liver cancer?

In the late stages of liver cancer, due to the spread of lesions, it is very easy to cause the failure of multiple organs such as the liver, heart, and kidneys, ultimately endangering the patient's life. Therefore, effective treatment methods must be adopted to delay the progression of the disease as much as possible. Currently, effective treatment methods include radiotherapy, chemotherapy, targeted therapy, immunotherapy, traditional Chinese medicine, and some physical therapies. Commonly used clinical treatments include radiofrequency ablation and microwave ablation. Radiotherapy is also a local treatment method, while targeted therapy and chemotherapy immunotherapy are systemic comprehensive treatments. Currently, the effects of targeted therapy for liver cancer are satisfactory, but the effects of chemotherapy and immunotherapy are poor. Most patients need these treatments combined to exert their effective anti-tumor treatment functions.

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The difference between primary liver cancer and metastatic liver cancer

Primary liver cancer refers to malignant tumors that originate in the liver, while metastatic liver cancer refers to cancers that start in other parts of the body and then spread to the liver through lymphatic and blood circulation, among other routes. Another difference is that primary liver cancer is more likely to be a single lesion, while metastatic liver cancer generally involves multiple lesions. Regarding the differences between primary and metastatic liver cancer, their treatment methods also differ. For primary liver cancer, interventional chemotherapy or surgery, such as hepatic lobectomy, can be performed if the tumor is small. In contrast, metastatic liver cancer usually involves multiple lesions, making surgery alone challenging. Additionally, the primary tumor also requires treatment.

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Will Hepatitis B with e-antigen positive develop into liver cancer?

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The difference between primary liver cancer and secondary liver cancer.

Primary liver cancer generally refers to tumors whose cancer cells originate from the liver itself or from the intrahepatic bile ducts. Secondary liver cancer usually refers to cancer that has metastasized to the liver from other parts of the body, which is the main difference between the two. Additionally, primary liver cancer might progress rapidly, potentially resulting in a short survival time, especially in cases of large, inoperable tumors, where most survival times range from half a year to about a year. In contrast, secondary liver cancer might have a longer survival time, and initial symptoms are generally milder. Also, tumor markers like alpha-fetoprotein (AFP) tend to be higher in primary liver cancer, whereas in secondary liver cancer, this marker may be normal.