Does early-stage liver cancer cause itchy skin?

Written by Yan Chun
Oncology
Updated on January 10, 2025
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Liver cancer is one of the common malignant tumors in the digestive system. In the early stages of liver cancer, most patients do not exhibit symptoms of skin itching. It is only when the cancer progresses and causes obstructive jaundice that patients clinically develop symptoms of skin itching. Early-stage liver cancer patients typically do not show typical clinical symptoms, or they may not have any significant symptoms at all. This is because early-stage liver cancer lesions are small and localized, without external invasion or metastasis. Therefore, the impact on the entire body is minimal, and clinically it generally manifests as mild abdominal bloating, discomfort, nausea, diarrhea, and some patients may experience a dull ache or discomfort in the liver area. Because the symptoms of early-stage liver cancer are atypical, many patients are already in the middle to late stages by the time they seek medical attention, missing the opportunity for clinical cure.

Other Voices

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Written by Cui Fang Bo
Oncology
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Will early-stage liver cancer cause a low-grade fever?

Patients with early-stage liver cancer may experience low-grade fevers, primarily due to the following two reasons: First, tumor fever. In the early stages of liver cancer, some tumor cells can release tumor mediators into the bloodstream, affecting the function of the temperature regulation center and causing the patient to develop a fever. This type of tumor fever is usually not very high, remaining below 38.5°C, without concurrent symptoms or signs of infection. A complete blood count typically indicates that the total number of white blood cells and the proportion of neutrophils are not elevated. The second scenario involves patients in the early stages of liver cancer experiencing fever due to concurrent infections. These patients often present with symptoms and signs related to infection, such as coughing up phlegm, abdominal pain and diarrhea, and urinary frequency, urgency, or pain. The proportion of white blood cells and neutrophils is significantly increased in these cases.

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Written by Yan Chun
Oncology
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What are the symptoms on the face in the early stages of liver cancer?

In early-stage liver cancer patients, symptoms generally do not appear on their faces. This is because the tumors in early liver cancer are small, the lesions are localized, with shallow infiltration, no invasion of surrounding tissues or metastasis to distant organs, and thus, less damage to liver cells. Therefore, most cases do not show obvious symptoms clinically. Only when the lesions progress further do symptoms of disease dissemination appear in patients. These symptoms include persistent pain in the liver area, a significant decrease in appetite, fatigue, fever, and weight loss. Some patients may also experience symptoms of metastatic lesions, such as pain in bone metastases, headache, vomiting, hemiplegia, and aphasia in brain metastases, and cough, breathing difficulties, and chest pain in lung metastases.

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Written by Sun Wei
Surgical Oncology
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The difference between primary liver cancer and secondary liver cancer

Primary liver cancer, also commonly referred to as liver cancer, originates in the liver itself and is not transferred from other parts of the body. Secondary liver cancer occurs when the primary tumor originates in another location and then metastasizes to the liver, causing hepatic space-occupying lesions; this is referred to as secondary liver cancer. The main difference between the two types is their origin. Additionally, primary liver cancer is often solitary but may develop intrahepatic or distant metastases as the disease progresses. In cases of secondary liver cancer, multiple intrahepatic metastatic lesions may be discovered at the onset. Moreover, primary liver cancer may often display an elevated alpha-fetoprotein tumor marker, whereas this marker might be normal in secondary liver cancer.

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Written by Ye Xi Yong
Infectious Diseases
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Will having hepatitis B antibodies lead to liver cancer?

Firstly, there is no necessary connection between liver cancer and antibodies, but if a patient has hepatitis B antibodies, then the chance of this patient contracting hepatitis B is very small. Relatively speaking, since hepatitis B can develop into liver cancer, having positive hepatitis B antibodies might reduce the chance of developing liver cancer. However, there are many types of liver cancer, and its causes are varied, including hepatitis B, hepatitis C, and other factors.

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Written by Liu Wu Cai
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Can liver calcifications be liver cancer?

Calcification in the liver is not liver cancer. For internal liver calcifications, it is described in ultrasonography and CT scans as a benign lesion, not as liver cancer. Liver cancer is a malignant tumor that can be life-threatening, thus it is considered a serious condition. When calcification is present, it is not indicative of liver cancer, but regular follow-up ultrasounds are still needed to monitor changes in size dynamically. If the calcification increases significantly in size over a short period and grows rapidly, malignant transformation should be suspected, and surgery should be conducted as soon as possible to improve the prognosis for the patient. Additionally, for liver cancer patients, it is advisable to avoid spicy and irritating foods to reduce inflammatory stimulation, which is more conducive to the recovery of the condition.