Does rickets affect development and intelligence?

Written by Mo Ming Hua
Pediatrics
Updated on March 18, 2025
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Rickets is primarily caused by a deficiency in vitamin D and mainly affects normal growth and development, with very little to no impact on intelligence. In the early stages of rickets, symptoms mainly include irritability, restlessness, and excessive sweating at night. The body primarily exhibits symptoms such as sweating, night terrors, and irritability, with symptoms becoming significantly more pronounced. During this period, the main manifestations are skeletal deformities, which vary in different age groups. For example, there can be softening of the skull, as well as pectus excavatum, pectus carinatum, and X-shaped or O-shaped legs. In severe cases, spinal deformities may also occur.

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Written by Yan Xin Liang
Pediatrics
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Does rickets have a hereditary component?

Rickets, also known as vitamin D deficiency rickets, is primarily a chronic nutritional disease characterized by skeletal lesions, caused by insufficient vitamin D in infants, children, or adolescents, which leads to disturbances in calcium and phosphorus metabolism. The main feature of this disease is the incomplete calcification of the growth plates and bone tissue in the growing long bones, due to the lack of vitamin D causing incomplete calcification of mature bones. This disease is most common in children under two years old. Its causes may be related to insufficient intake of vitamin D or insufficient sunlight exposure, as well as rapid growth. Additionally, other diseases may influence its development. Therefore, this disease is generally not closely related to genetics.

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Written by Yao Li Qin
Pediatrics
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How is rickets treated with injections?

Rickets, also known as vitamin D deficiency rickets, is a chronic nutritional disease characterized by skeletal lesions, caused by insufficient vitamin D in children, leading to disturbances in calcium and phosphorus metabolism. The typical manifestation of rickets is incomplete mineralization of the growing long bone epiphyses and bone tissue, presenting as bone softening or deformity. Once rickets is diagnosed, it must be treated aggressively. First, children are given high doses of vitamin D, either orally or through intramuscular injection, with a common practice of administering a single dose of 300,000 units of vitamin D intramuscularly. A month later, a blood sample is taken to measure the vitamin D content; if it is below normal, treatment must continue; if it is within the normal range, it is only necessary to supplement the daily physiological requirement of vitamin D for the child. (Specific medication should be administered under the guidance of a physician.)

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Written by Li Jiao Yan
Neonatology
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What are the symptoms of rickets?

The condition generally referred to as rickets is most commonly nutritional vitamin D deficiency rickets, a type of nutritional disease that is prevalent among infants and young children, particularly very young babies. It primarily manifests as changes in the bones where growth is most rapid and can also affect muscle development and changes in nervous excitability. Initially, especially within the first three months, symptoms in very young infants typically include increased nervous excitability, such as crying easily, excessive head sweating, and as a result of the sweating, frequent head shaking, irritability, restlessness, and noticeable crying and restlessness at night. These symptoms at this stage are not necessarily indicative of typical rickets. As the condition progresses, changes in the skeleton gradually become apparent. In infants under six months with rickets, the changes are mainly in the skull, typically feeling like pressing on a ping-pong ball. After six months of age, the head shape becomes squared or box-like, and the head circumference is larger than normal. Later, the characteristic beading changes of rickets appear, with beaded protrusions above the ribs, followed by the formation of blunt, circular raised areas at the wrists and ankles, referred to as wrist and ankle bracelets. Around the age of one, infants may develop a deformity resembling pigeon chest. As the child begins to stand and walk, the weight bearing on the lower limbs may lead to deformities, such as bowlegs or knock-knees, and sometimes even K-shaped deformities of the legs, and some might develop spinal deformities.

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Written by Li Jiao Yan
Neonatology
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Early clinical manifestations of rickets

Early Symptoms of Rickets: Rickets is a chronic nutritional disease caused by a deficiency in Vitamin D, leading to disordered calcium and phosphorus metabolism and resulting in abnormal skeletal development. It primarily affects infants, especially those under six months old, with the highest occurrence in infants under three months. The general symptoms include heightened neural excitability, such as fussiness, easy irritability, sudden bouts of crying, or being so sensitive that they cry when touched. Other symptoms include excessive sweating and frequent head shaking, though these are not specific indicators of rickets. Diagnosis mainly relies on biochemical markers and Vitamin D levels, like decreased blood calcium and phosphorus levels, elevated parathyroid hormone levels, and reduced 25-hydroxy-D3. X-ray images of bones might appear normal.

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Written by Tong Peng
Pediatrics
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Can people with rickets swim?

Rickets is a metabolic disease caused by a deficiency in vitamin D, and its clinical manifestations primarily include symptoms in infants such as a square skull, night sweats, pigeon chest, eversion of the rib cage, as well as bowlegs or knock-knees. Severe cases can lead to skeletal deformities in the chest and developmental disorders. Therefore, for the treatment of children with rickets, it is necessary to intake vitamin D and calcium to promote bone development. Swimming is also a form of exercise that can enhance the absorption of calcium by the bones, which can help prevent the progression of rickets. It is also important to engage in outdoor activities and expose to sunlight, as vitamin D can be synthesized through sun exposure, effectively supplementing it. If a child's symptoms of rickets are relatively severe, it is advisable to take the child to a specialist hospital for a 25-hydroxy vitamin D test and supplement vitamin D based on the specific results.