Can rickets be inherited by the next generation?

Written by Li Jiao Yan
Neonatology
Updated on April 24, 2025
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Rickets, called vitamin D-deficiency rickets, is caused by a lack of vitamin D which leads to abnormal calcium and phosphorus metabolism in the body. This prevents calcium salts from properly depositing in the growing parts of the skeleton, resulting in incomplete mineralization of bone tissue during growth. It produces a systemic, chronic nutritional disease characterized by skeletal lesions and closely related to lifestyle. The primary causes of rickets are due to a combination of factors leading to vitamin D deficiency. Feeding methods, cod liver oil supplementation, living environment, time spent outdoors, recurrent respiratory infections, maternal calcium deficiency during pregnancy, and the season of birth are all significant contributing factors to the incidence of rickets. Generally, most cases of rickets are not inherited to the next generation. However, if there is a clear hereditary disease causing insufficient levels of vitamin D, it could potentially be inherited by the next generation.

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Written by Li Jiao Yan
Neonatology
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Which department should I go to for rickets?

Rickets is a nutritional disease caused by a deficiency in vitamin D, leading to disturbances in calcium and phosphorus metabolism and resulting in abnormal bone development. During the early and active stages, the X-ray shows no obvious abnormalities in bone development; it is primarily a conceptual metabolic disorder along with low levels of vitamin D. At this time, it is advisable to consult an endocrinology department. If there are sequelae and mild to moderate sequelae, rehabilitation methods are needed for correction, and at this point, a rehabilitation department should be consulted. If there are severe skeletal deformities, surgical correction may be necessary, and at this time, an orthopedic department should be consulted.

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Written by Tong Peng
Pediatrics
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Can rickets be treated with vitamin D3?

Rickets can be treated with Vitamin D3; first, we need to understand the pathology of the disease. It is a metabolic, obstructive disease caused by a deficiency of Vitamin D. Often, this deficiency leads to impaired calcium absorption in the body, causing osteoporosis and bone deformity. Infants typically exhibit symptoms like square skulls, pigeon chests, outward flaring ribs, bow legs, and knock knees. Additionally, it affects the baby's sleep quality. The lack of Vitamin D can increase the baby's neural excitability, leading to poor sleep and easy waking. Moreover, severe cases can affect growth and development. Presence of these symptoms should be confirmed by laboratory testing of 25-hydroxy Vitamin D3 to determine specific levels and choose the appropriate dose of Vitamin D3 supplementation. It is also encouraged to promote children's physical activity and exposure to sunlight to enhance the body's synthesis of Vitamin D, which is beneficial for bone development. (Medication should be administered under the guidance of a professional doctor.)

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Written by Tong Peng
Pediatrics
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Does rickets have anything to do with milk powder?

Rickets is not necessarily linked to formula milk. Rickets is mainly a metabolic bone disease caused by a deficiency of vitamin D in the body, while the main components of formula milk are various nutrients, including trace elements and vitamins. If the formula contains insufficient calcium, it may exacerbate the symptoms of rickets. Therefore, the main requirement is to intake enough vitamin D. National child healthcare guidelines require that children be supplemented with 400 to 800 units of vitamin D daily from two weeks after birth until the age of two. Additionally, it is important to get ample sunlight in daily life and engage in reasonable outdoor activities to promote calcium absorption, which can effectively prevent rickets. The amount of vitamin D and calcium in formula milk cannot meet the growth and developmental needs of children, so additional supplementation is necessary. Thus, there is a certain connection between rickets and formula milk, but it is not inevitable.

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Written by Li Jiao Yan
Neonatology
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How to treat rickets in a 2-year-old baby?

Rickets in two-year-old infants is caused by a deficiency in vitamin D leading to a disturbance in calcium and phosphorus metabolism, resulting in abnormal skeletal development. This class of systemic, chronic, nutritional diseases typically manifests in two-year-olds who are able to walk and stand. Due to the force of gravity, lower limb deformities may develop, leading to bowlegs or knock-knees, and possibly even a 'K'-shaped limb deformity. The spine may also develop kyphosis or scoliosis. Around the age of two, it is generally the residual stage of the disease, which often does not require pharmacological treatment. For mild to moderate cases, physical exercise should be enhanced, and active or passive rehabilitation methods should be used to correct skeletal deformities. It is recommended to seek treatment in the pediatric rehabilitation department; severe skeletal deformities may require surgical correction.

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Written by Li Jiao Yan
Neonatology
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What are the symptoms of rickets?

The condition generally referred to as rickets is most commonly nutritional vitamin D deficiency rickets, a type of nutritional disease that is prevalent among infants and young children, particularly very young babies. It primarily manifests as changes in the bones where growth is most rapid and can also affect muscle development and changes in nervous excitability. Initially, especially within the first three months, symptoms in very young infants typically include increased nervous excitability, such as crying easily, excessive head sweating, and as a result of the sweating, frequent head shaking, irritability, restlessness, and noticeable crying and restlessness at night. These symptoms at this stage are not necessarily indicative of typical rickets. As the condition progresses, changes in the skeleton gradually become apparent. In infants under six months with rickets, the changes are mainly in the skull, typically feeling like pressing on a ping-pong ball. After six months of age, the head shape becomes squared or box-like, and the head circumference is larger than normal. Later, the characteristic beading changes of rickets appear, with beaded protrusions above the ribs, followed by the formation of blunt, circular raised areas at the wrists and ankles, referred to as wrist and ankle bracelets. Around the age of one, infants may develop a deformity resembling pigeon chest. As the child begins to stand and walk, the weight bearing on the lower limbs may lead to deformities, such as bowlegs or knock-knees, and sometimes even K-shaped deformities of the legs, and some might develop spinal deformities.