Can rickets be inherited by the next generation?

Written by Li Jiao Yan
Neonatology
Updated on April 24, 2025
00:00
00:00

Rickets, called vitamin D-deficiency rickets, is caused by a lack of vitamin D which leads to abnormal calcium and phosphorus metabolism in the body. This prevents calcium salts from properly depositing in the growing parts of the skeleton, resulting in incomplete mineralization of bone tissue during growth. It produces a systemic, chronic nutritional disease characterized by skeletal lesions and closely related to lifestyle. The primary causes of rickets are due to a combination of factors leading to vitamin D deficiency. Feeding methods, cod liver oil supplementation, living environment, time spent outdoors, recurrent respiratory infections, maternal calcium deficiency during pregnancy, and the season of birth are all significant contributing factors to the incidence of rickets. Generally, most cases of rickets are not inherited to the next generation. However, if there is a clear hereditary disease causing insufficient levels of vitamin D, it could potentially be inherited by the next generation.

Other Voices

doctor image
home-news-image
Written by Li Jiao Yan
Neonatology
1min 58sec home-news-image

Rickets symptoms

Rickets, also known as nutritional vitamin D deficiency rickets, is a chronic nutritional disease in children caused by inadequate vitamin D in their bodies, leading to disorders in calcium and phosphorus metabolism and characterized by changes in the growth plates. Its manifestation varies with different ages. In infants under six months, especially those under three months, symptoms often include increased nervous excitability, such as being easily irritable, restless, sweating, and shaking their heads due to scalp irritation. As the condition progresses in children under six months, the primary changes are seen in the skull; the edges of the anterior fontanelle are softer, and the skull is thinner. After six months, the softening of the skull disappears, but there can be ping-pong ball-like changes around the skull, leading to a box-shaped head from seven to eight months. Gradually, beading changes form, most notably around the 7th to 10th ribs. Around the age of one, children can develop a pigeon chest deformity, and in severe cases of rickets, a horizontal depression forms at the lower edge of the thoracic cage, known as the costal groove or Harrison's groove. Due to bone softening and muscle and joint laxity, when the child begins to stand and walk, the legs may become bow-legged or X-shaped, and in severe cases, can develop into 'K'-shaped leg deformities. Once the child starts to sit and stand, general ligament laxity can cause spinal deformities. Severe hypophosphatemia leads to muscle carbohydrate metabolism disorder, resulting in overall muscle laxity, decreased muscle tone, and subsequently reduced muscle strength.

doctor image
home-news-image
Written by Yao Li Qin
Pediatrics
1min 16sec home-news-image

The main manifestations of rickets in the early stage

Rickets generally refers to vitamin D deficiency rickets, mainly due to insufficient vitamin D in children, leading to calcium and phosphorus metabolism disorders. It is a chronic nutritional disease characterized by skeletal lesions. The main manifestations are changes in the fastest growing parts of the skeleton, which can also affect muscle development and changes in neural excitability. The initial symptoms of rickets are common in infants, especially those under three months old. The main symptom is increased neural excitability; the child is particularly prone to being agitated, irritable, crying, sweating, and shaking their head due to scalp stimulation, but these are not specific symptoms of rickets. Therefore, blood tests are still necessary in the early stages, showing decreased levels of 25-hydroxyvitamin D3, blood calcium, and blood phosphate, increased PTH, normal or slightly elevated alkaline phosphatase activity, and normal or slightly blurry calcification zones in skeletal X-rays. These are the early manifestations of rickets.

doctor image
home-news-image
Written by Tong Peng
Pediatrics
56sec home-news-image

Will the frontal bossing from rickets get better?

Rickets, if presenting with frontal bossing, can recover depending on the specific condition and age of the child. Rickets is often divided into four stages, with sequelae usually occurring after the age of three. Therefore, if symptoms of rickets are present before the age of three, they can be alleviated through supplementation with vitamin D, calcium, and other trace elements. Symptoms of rickets include craniotabes, Harrison's groove, beading of the ribs, pigeon chest, everted ribs, bowlegs, and knock-knees. Frontal bossing is often a manifestation of craniotabes, which usually occurs during infancy. Supplementing with vitamin D during this period can greatly alleviate the condition. At the same time, it is important to also expose the child to sunlight and engage in outdoor activities to promote the bones' absorption of vitamin D and calcium, preventing the recurrence of symptoms.

doctor image
home-news-image
Written by Li Jiao Yan
Neonatology
50sec home-news-image

Which department should I go to for rickets?

Rickets, known as nutritional vitamin D deficiency rickets, is a chronic nutritional disease characterized by skeletal lesions, caused by a deficiency of vitamin D in the body leading to disturbed calcium and phosphate metabolism. In the early stages of rickets, it is primarily due to insufficient levels of vitamin D, which then leads to abnormal calcium and phosphate metabolism; at this stage, it is necessary to consult the endocrinology department to correct it timely. If rickets has already caused developmental deformities of the bones, orthopedic consultation is required for corrective treatment. For instance, if children exhibit pigeon chest, or noticeable bow legs or knock knees, they need to see an orthopedic specialist.

doctor image
home-news-image
Written by Liu Li
Pediatrics
36sec home-news-image

Is cod liver oil useful for rickets?

Cod liver oil is very effective in preventing rickets because its main components are vitamin D and vitamin A. If babies take cod liver oil, it can help promote the body's absorption of calcium and phosphorus. Cod liver oil not only prevents rickets but also promotes the growth and development of children, prevents delayed bone development, and avoids issues such as incomplete teeth. It can greatly help babies grow up healthy and happy. (The use of medication should be conducted under the guidance of a professional doctor.)