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Yan Chun
Oncology
About me
Graduated from the Clinical Medicine Department of Qingdao Medical College, has been working in the Oncology Department since 2001, obtained the qualification of attending physician in the same year. Promoted to attending physician in 2003. Qualified as associate chief physician in 2011. Participated in advanced studies at Jinan Cancer Hospital from June to November 2015. Serves as a youth member of the Chemical Therapy Committee in Shandong Province, youth member of the Elderly Therapy Committee of the Qingdao Anti-cancer Association, and a member of the Biologic Therapy Committee of the Qingdao Anti-cancer Association.
Proficient in diseases
Chemotherapy, radiotherapy, deep hyperthermia, targeted therapy, and endocrine therapy for various tumors such as stomach cancer, colorectal cancer, lung cancer, breast cancer, ovarian cancer, and pancreatic cancer.
Voices
How to effectively treat advanced liver cancer?
In the late stages of liver cancer, due to the spread of lesions, it is very easy to cause the failure of multiple organs such as the liver, heart, and kidneys, ultimately endangering the patient's life. Therefore, effective treatment methods must be adopted to delay the progression of the disease as much as possible. Currently, effective treatment methods include radiotherapy, chemotherapy, targeted therapy, immunotherapy, traditional Chinese medicine, and some physical therapies. Commonly used clinical treatments include radiofrequency ablation and microwave ablation. Radiotherapy is also a local treatment method, while targeted therapy and chemotherapy immunotherapy are systemic comprehensive treatments. Currently, the effects of targeted therapy for liver cancer are satisfactory, but the effects of chemotherapy and immunotherapy are poor. Most patients need these treatments combined to exert their effective anti-tumor treatment functions.
Early symptoms of ovarian cancer
The early clinical symptoms of ovarian cancer primarily include the following aspects: 1. Discomfort and dull pain in the lower abdomen, with some patients experiencing a sensation of heaviness in the pelvis. Alongside this, patients may also experience poor appetite, nausea, belching, and a feeling of bloating in the stomach. 2. A sensation of abdominal fullness is a clinical manifestation that can appear early in ovarian cancer patients, often caused by cancerous ascites due to the disease. 3. In very few cases, early-stage ovarian cancer patients may feel a mass in the abdomen, typically in leaner patients. 4. Some early-stage patients may experience mild abdominal pain, which generally occurs intermittently and can resolve on its own without the need for medication. 5. Patients may exhibit menstrual irregularities and some endocrine symptoms, such as vaginal bleeding.
Does kidney cancer affect the renal calyx?
Kidney cancer lesions can sometimes affect the renal calyces. This is because kidney cancer is a malignant disease characterized by invasion and metastasis. When the lesions from kidney cancer invade the surrounding renal tissues, this can impact the function of the renal calyces. Some patients may experience toxic side effects from chemotherapy, targeted therapy, and other related antitumor treatments for kidney cancer, which can also affect the renal calyces. In summary, the lesions from kidney cancer and related antitumor treatments can potentially affect and even lead to clinical manifestations of kidney damage, including complications such as hydronephrosis. Once the kidney cancer lesions affect the renal calyces, this can result in sequelae such as renal failure.
Can liver cancer cause back pain?
Liver cancer can potentially cause back pain for several reasons: First, the tumor from liver cancer may directly metastasize to locations such as the lumbar vertebrae, resulting in significant and persistent back pain. Second, liver cancer can metastasize to the kidneys via the bloodstream, which clinically can also manifest as back pain and symptoms of blood in the urine. Third, liver cancer can cause kidney function impairment, which likewise can lead to symptoms of back pain. Fourth, patients with liver cancer may experience back pain due to urinary tract infections, which can appear particularly when the infection is severe and the patient's immune system is compromised.
Does T3 laryngeal cancer require total laryngectomy?
In clinical practice, most patients with stage T3 laryngeal cancer require total laryngectomy. Postoperative measures include voice reconstruction and rehabilitation exercises to ensure the quality of life after surgery. This is because stage T3 laryngeal cancer implies that the cancer has extended beyond the local area of the larynx and has affected one vocal cord. To ensure the radical nature of the surgery, a total laryngectomy is necessary for patients who have advanced to stage T3. However, this type of surgery can lead to postoperative functional impairments such as speech difficulties. Therefore, it is recommended that patients begin functional exercises very early post-surgery.
Can late-stage colon cancer be completely removed by surgery?
In clinical practice, for patients with mid-to-late-stage colon cancer, even after curative surgical resection, it is often difficult to completely remove the tumor. This is because by the mid-to-late stages, the colon cancer has typically started to invade surrounding tissues. Despite curative surgery, patients may still have subclinical lesions, which are typically hard to detect either under a microscope or with the naked eye. The presence of these subclinical lesions leads to a higher likelihood of recurrence and metastasis after curative surgery in mid-to-late-stage colon cancer patients. Therefore, to reduce the rates of recurrence and metastasis, it is common clinical practice to administer adjuvant chemotherapy and radiotherapy after the curative surgical resection for patients with mid-to-late-stage colon cancer, aiming to decrease the risk of cancer recurrence and metastasis.
What are the early symptoms of ovarian cancer?
Patients with ovarian cancer often do not exhibit many symptoms in the early stages, and many do not have obvious symptoms initially. Some patients may experience pelvic pain due to tumor growth early on, primarily located in the bilateral pelvic area, with some experiencing pain that radiates to the perineal area. Some early-stage ovarian cancer patients may experience abnormalities in their menstrual cycle, primarily manifested as irregular menstruation, increased menstrual flow, and the presence of blood clots. Some patients may also experience abnormal vaginal bleeding outside of their menstrual period. In addition, some patients in the early stages may exhibit signs of abnormal hormone secretion. Aside from these, most early-stage ovarian cancer patients do not show obvious symptoms.
What should I do about oral cancer causing facial perforation?
Patients with oral cancer presenting with facial perforation symptoms can be treated with the following clinical methods: First, local dressing changes should be performed on the perforated facial tissue. Topically applied antibiotics can be used to prevent and treat infections caused by the perforation. Additionally, topical anesthetics can be applied to alleviate pain. Second, as facial perforations are often due to cancerous tissue damage, considering the application of topical chemotherapy drugs can promote the shrinkage of cancerous lesions at the perforation site, which is beneficial for the growth of normal tissues.
Do early-stage liver cancer patients experience fatigue?
Patients with early-stage liver cancer generally do not exhibit symptoms of fatigue, which are more commonly seen in patients with mid to late-stage liver cancer. The clinical symptoms of early-stage liver cancer are generally not typical, with a minority of patients experiencing reduced appetite and discomfort or mild pain in the liver area. Furthermore, early-stage liver cancer is often discovered during physical examinations or incidentally. Fatigue in liver cancer patients is mostly due to hypoalbuminemia, moderate to severe anemia, or toxic side effects caused by certain anticancer treatments. Hypoalbuminemia occurs because the growth of liver cancer consumes a large amount of protein, and liver dysfunction leads to insufficient synthesis of both protein and glycogen, resulting in malnutrition in patients. After experiencing weight loss, patients often show signs of fatigue. The pathological changes in liver cancer can lead to moderate to severe anemia, which, in turn, significantly contributes to fatigue. Additionally, some medications used in treating liver cancer can cause fatigue due to their toxic side effects.
How to treat bone metastasis in advanced prostate cancer?
For cases of advanced prostate cancer with bone metastasis, the following clinical treatment measures can be taken: Firstly, for the pain caused by bone metastatic lesions, symptomatic pain relief treatment should be administered with medication. The pain from bone metastatic lesions generally presents as moderate to severe, and medications usually involve weak or strong opioids for pain relief. For some patients with advanced bone metastases, pathological fractures may occur, necessitating treatments such as bone stabilization and bone cement. For some patients with advanced bone metastasis from prostate cancer, monthly injections of zoledronic acid can also be administered to treat the bone metastases. When prostate cancer has metastasized to the bone, it indicates that the disease is at an advanced stage, and the opportunity for curative surgery is lost. In most cases, treatments such as targeted therapy and endocrine therapy are adopted as conservative medical approaches.