Can hypothyroidism in women lead to thyroid cancer?

Written by Gan Jun
Endocrinology
Updated on March 24, 2025
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Women with hypothyroidism generally do not develop thyroid tumors, as there is no necessary correlation between the two. Hypothyroidism is caused by a decrease in the synthesis and secretion of thyroid hormones in the body, leading to a series of symptoms associated with a slowed metabolic rate. The occurrence of hypothyroidism is due to a reduction in the synthesis and secretion of thyroid hormones, while thyroid cancer is mainly due to a change in the nature of the thyroid tissue. Decreased thyroid function is caused by an abnormality in thyroid secretion function. Therefore, it is advised that such patients should not worry too much, avoid placing too much mental and psychological stress on themselves, maintain a good daily routine, avoid staying up late, smoking, or drinking alcohol, and regularly review their thyroid ultrasound and thyroid function to dynamically observe the occurrence and development of thyroid diseases.

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Written by Gong Chun
Oncology
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How is thyroid cancer diagnosed?

The first point is the diagnostic process for differentiated thyroid cancer. Initially, most patients may not have symptoms, while a minority might show symptoms due to invasion of surrounding organs. Ultrasound examination is the preferred method for diagnosing thyroid nodules. Ultrasound can clarify the number, nature, and location of thyroid nodules, as well as provide information on whether there are abnormally enlarged lymph nodes in the neck. It has a relatively high accuracy in identifying the nature of thyroid nodules. Currently, the most accurate test for determining the nature of thyroid nodules remains the fine needle aspiration cytology, which has a diagnostic sensitivity of 83-92% and specificity of 80-92%, but it is not 100% conclusive. The second point is about the diagnosis of medullary thyroid cancer. Besides the tests common for thyroid cancers, additional tests for medullary thyroid cancer can include fine needle aspiration, ultrasound, and some serological tests, such as calcitonin and carcinoembryonic antigen tests.

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Written by Gong Chun
Oncology
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Late-stage symptoms of thyroid cancer

Differentiated thyroid cancer, in its advanced stages, can exhibit noticeable symptoms due to large nodules or invasion of surrounding organs. For example, a massive nodule pressing on the trachea can cause breathing difficulties, including respiratory distress. Compression of the esophagus can lead to swallowing difficulties, and pressure on the recurrent laryngeal nerve may result in symptoms like hoarseness. Even very few benign thyroid nodules can cause edema and inflammation by compressing these nerves. Therefore, differentiation and distinctive treatment are essential, along with a pathological diagnosis. Medullary thyroid cancer also presents specific symptoms, including persistent diarrhea, endocrine syndromes, and other accompanying conditions such as pheochromocytoma, multiple mucosal neuromas, and symptoms and signs caused by parathyroid adenomas.

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Written by Cui Fang Bo
Oncology
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Is thyroid cancer without lymph node metastasis considered early stage?

Thyroid cancer, if it has not metastasized to lymph nodes, generally falls under early-stage. Once thyroid cancer is diagnosed, surgical removal is the primary treatment choice. Postoperative treatments vary depending on the different pathological types of thyroid cancer. For the most common type, papillary carcinoma, if the surgery is radically curative, further treatment may not be necessary, and merely supplementing thyroid hormones suffices. In cases such as follicular carcinoma, undifferentiated carcinoma, or medullary carcinoma, even after surgically radical removal, postoperative treatment often requires further radiotherapy or treatment with Iodine-131, depending on the surgical pathology results. (The use of medications should be carried out under the guidance of a professional doctor.)

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Written by Gong Chun
Oncology
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Thyroid cancer ultrasound manifestations

The characteristics of ultrasonography for thyroid cancer include the tumor being a solid hypoechoic mass with unclear boundaries, uneven internal echoes, abundant internal blood flow, and the presence of sandy calcifications and longitudinal growth, among others. Currently, ultrasonography is the preferred method for examining thyroid nodules. It can clearly identify the number, nature, and location of thyroid nodules, as well as whether there are any abnormally enlarged lymph nodes in the neck. Ultrasonography is highly accurate in differentiating the nature of thyroid nodules, with experienced ultrasonographers reaching an accuracy rate of over 80%. However, the highest accuracy in differentiating the nature of thyroid nodules is still achieved with fine-needle aspiration cytology.

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Written by Gan Jun
Endocrinology
1min 2sec home-news-image

Can hypothyroidism in women lead to thyroid cancer?

Women with hypothyroidism generally do not develop thyroid tumors, as there is no necessary correlation between the two. Hypothyroidism is caused by a decrease in the synthesis and secretion of thyroid hormones in the body, leading to a series of symptoms associated with a slowed metabolic rate. The occurrence of hypothyroidism is due to a reduction in the synthesis and secretion of thyroid hormones, while thyroid cancer is mainly due to a change in the nature of the thyroid tissue. Decreased thyroid function is caused by an abnormality in thyroid secretion function. Therefore, it is advised that such patients should not worry too much, avoid placing too much mental and psychological stress on themselves, maintain a good daily routine, avoid staying up late, smoking, or drinking alcohol, and regularly review their thyroid ultrasound and thyroid function to dynamically observe the occurrence and development of thyroid diseases.