Thyroid cancer ultrasound manifestations

Written by Gong Chun
Oncology
Updated on September 02, 2024
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The characteristics of ultrasonography for thyroid cancer include the tumor being a solid hypoechoic mass with unclear boundaries, uneven internal echoes, abundant internal blood flow, and the presence of sandy calcifications and longitudinal growth, among others. Currently, ultrasonography is the preferred method for examining thyroid nodules. It can clearly identify the number, nature, and location of thyroid nodules, as well as whether there are any abnormally enlarged lymph nodes in the neck. Ultrasonography is highly accurate in differentiating the nature of thyroid nodules, with experienced ultrasonographers reaching an accuracy rate of over 80%. However, the highest accuracy in differentiating the nature of thyroid nodules is still achieved with fine-needle aspiration cytology.

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Written by Gong Chun
Oncology
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How is thyroid cancer diagnosed?

The first point is the diagnostic process for differentiated thyroid cancer. Initially, most patients may not have symptoms, while a minority might show symptoms due to invasion of surrounding organs. Ultrasound examination is the preferred method for diagnosing thyroid nodules. Ultrasound can clarify the number, nature, and location of thyroid nodules, as well as provide information on whether there are abnormally enlarged lymph nodes in the neck. It has a relatively high accuracy in identifying the nature of thyroid nodules. Currently, the most accurate test for determining the nature of thyroid nodules remains the fine needle aspiration cytology, which has a diagnostic sensitivity of 83-92% and specificity of 80-92%, but it is not 100% conclusive. The second point is about the diagnosis of medullary thyroid cancer. Besides the tests common for thyroid cancers, additional tests for medullary thyroid cancer can include fine needle aspiration, ultrasound, and some serological tests, such as calcitonin and carcinoembryonic antigen tests.

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Written by Chen Xie
Endocrinology
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What are the clinical manifestations of thyroid cancer?

For patients with thyroid cancer, the most common clinical manifestation is thyroid nodules, and most patients do not have obvious clinical symptoms, only being incidentally discovered during physical examinations. In rare cases, patients may seek medical attention due to enlarged cervical lymph nodes. As the condition progresses, the neck mass gradually enlarges, becomes firmer, and its mobility decreases during swallowing. In some rapid developments, it may invade surrounding tissues, leading to late-stage symptoms such as hoarseness, difficulty breathing, and difficulty swallowing. When the cervical sympathetic nerve is compressed, it can cause pain in the ears, occipital region, and shoulders. In the case of medullary carcinoma, which can produce serotonin and calcitonin, patients may sometimes experience symptoms such as diarrhea, palpitations, facial flushing, or decreased blood calcium levels.

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Written by Gan Jun
Endocrinology
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Characteristics of thyroid cancer lymph node enlargement

Thyroid cancer is a type of malignant tumor. However, if it is detected early, diagnosed early, and treated early, it generally has a relatively good prognosis compared to other malignant tumors. Once a patient is afflicted with this disease, it is crucial to seek treatment promptly. Without treatment, thyroid cancer can spread to lymph nodes. Initially, the cancerous lymph nodes may invade surrounding blood vessels and nerves, leading to symptoms such as hoarseness. If it compresses the throat area, it can cause discomfort in the throat accompanied by breathing difficulties and coughing while drinking. If the optimal time for treatment is missed, cancer cells can spread, potentially moving not only to the lungs but also to the respiratory system and bones, among other distant sites.

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Written by Gong Chun
Oncology
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How is thyroid cancer caused?

The causes of thyroid cancer are similar to those of most other malignancies. The etiology of thyroid cancer is not yet clear, but some factors are found to be associated with its occurrence: The first is neck radiation. The thyroid is an endocrine organ, sensitive to radiation. Radiation exposure can potentially cause thyroid cells to become cancerous, especially in those who received high doses of neck radiation in childhood and are more susceptible to thyroid cancer. The second factor is genetics; some thyroid cancers have a clear genetic predisposition, the most typical being medullary thyroid cancer. The third point is that the rapid increase in the incidence rate of thyroid cancer is partly due to the advancement in early diagnostic techniques, allowing for the detection of many early-stage lesions. Of course, iodine intake has already been shown to be related to some benign thyroid conditions. However, its relationship with thyroid cancer requires further study.

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Written by Zhao Xin Lan
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Differences between the symptoms of thyroiditis and thyroid cancer

Thyroiditis, if it is acute suppurative thyroiditis, clinical manifestations include fever, local pain in the thyroid, tenderness on palpation, and a hard texture of the thyroid. Examination will show an increase in white blood cells. Subacute thyroiditis may also present with mild fever or high fever and local pain in the thyroid, but compared to suppurative thyroiditis, the increase in white blood cell levels is not as significant in subacute thyroiditis. If it is autoimmune thyroiditis, there may not be obvious symptoms clinically; there may be enlargement of the thyroid, and the thyroid may feel tougher upon palpation. As for thyroid cancer, clinically, if it does not cause hyperthyroidism or hypothyroidism, there are no specific symptoms. When the cancerous tumor is large, there may be an enlargement of the thyroid, the texture of the enlarged thyroid will be very hard, and there will be notable local adhesions. Of course, the main difference can be detected and diagnosed through an ultrasound examination.