Is thyroid cancer without lymph node metastasis considered early stage?

Written by Cui Fang Bo
Oncology
Updated on September 16, 2024
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Thyroid cancer, if it has not metastasized to lymph nodes, generally falls under early-stage. Once thyroid cancer is diagnosed, surgical removal is the primary treatment choice. Postoperative treatments vary depending on the different pathological types of thyroid cancer. For the most common type, papillary carcinoma, if the surgery is radically curative, further treatment may not be necessary, and merely supplementing thyroid hormones suffices. In cases such as follicular carcinoma, undifferentiated carcinoma, or medullary carcinoma, even after surgically radical removal, postoperative treatment often requires further radiotherapy or treatment with Iodine-131, depending on the surgical pathology results. (The use of medications should be carried out under the guidance of a professional doctor.)

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Written by Gong Chun
Oncology
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Late-stage symptoms of thyroid cancer

Differentiated thyroid cancer, in its advanced stages, can exhibit noticeable symptoms due to large nodules or invasion of surrounding organs. For example, a massive nodule pressing on the trachea can cause breathing difficulties, including respiratory distress. Compression of the esophagus can lead to swallowing difficulties, and pressure on the recurrent laryngeal nerve may result in symptoms like hoarseness. Even very few benign thyroid nodules can cause edema and inflammation by compressing these nerves. Therefore, differentiation and distinctive treatment are essential, along with a pathological diagnosis. Medullary thyroid cancer also presents specific symptoms, including persistent diarrhea, endocrine syndromes, and other accompanying conditions such as pheochromocytoma, multiple mucosal neuromas, and symptoms and signs caused by parathyroid adenomas.

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Written by Gan Jun
Endocrinology
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Can hypothyroidism in women lead to thyroid cancer?

Women with hypothyroidism generally do not develop thyroid tumors, as there is no necessary correlation between the two. Hypothyroidism is caused by a decrease in the synthesis and secretion of thyroid hormones in the body, leading to a series of symptoms associated with a slowed metabolic rate. The occurrence of hypothyroidism is due to a reduction in the synthesis and secretion of thyroid hormones, while thyroid cancer is mainly due to a change in the nature of the thyroid tissue. Decreased thyroid function is caused by an abnormality in thyroid secretion function. Therefore, it is advised that such patients should not worry too much, avoid placing too much mental and psychological stress on themselves, maintain a good daily routine, avoid staying up late, smoking, or drinking alcohol, and regularly review their thyroid ultrasound and thyroid function to dynamically observe the occurrence and development of thyroid diseases.

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Written by Gong Chun
Oncology
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How is thyroid cancer caused?

The causes of thyroid cancer are similar to those of most other malignancies. The etiology of thyroid cancer is not yet clear, but some factors are found to be associated with its occurrence: The first is neck radiation. The thyroid is an endocrine organ, sensitive to radiation. Radiation exposure can potentially cause thyroid cells to become cancerous, especially in those who received high doses of neck radiation in childhood and are more susceptible to thyroid cancer. The second factor is genetics; some thyroid cancers have a clear genetic predisposition, the most typical being medullary thyroid cancer. The third point is that the rapid increase in the incidence rate of thyroid cancer is partly due to the advancement in early diagnostic techniques, allowing for the detection of many early-stage lesions. Of course, iodine intake has already been shown to be related to some benign thyroid conditions. However, its relationship with thyroid cancer requires further study.

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Written by Yan Chun
Oncology
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What are the early symptoms of thyroid cancer?

Thyroid cancer is a common malignant tumor in the head and neck area. The early symptoms of thyroid cancer are highly atypical, and many patients do not present clear early symptoms. Often, patients discover painless nodules in the thyroid incidentally during physical examinations; these nodules can move up and down with swallowing motions. In a minority of cases, when the nodules of early-stage thyroid cancer are large, they can cause hoarseness or coughing and choking when drinking water. Some patients might experience intermittent, hidden pain in the thyroid area during the early stages, which often resolves on its own without treatment. Besides these, in its early stages, thyroid cancer may not present other obvious symptoms. As the condition progresses, significant clinical symptoms appear only when the tumor invades surrounding structures or metastasizes to distant sites.

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Written by Gong Chun
Oncology
1min 4sec home-news-image

Early symptoms of thyroid cancer

Differentiated thyroid cancer often has no symptoms in the early stages, with only incidental palpation of nodules of various sizes and textures on the front of the neck. Some patients may find abnormalities during routine physical examinations through imaging studies, and symptoms may appear only in the later stages. The second point concerns the characteristics of medullary thyroid cancer, which exhibits specific symptoms early on, such as persistent, watery diarrhea. Additionally, this cancer involves an endocrine syndrome, where tumor cells secrete calcitonin and adrenocorticotropic hormone, potentially leading to facial flushing, elevated blood pressure, and reduced blood calcium. This may be associated with other conditions such as pheochromocytoma, multiple mucosal neuromas, and parathyroid adenomas, which can also cause corresponding symptoms.