How to Treat Calcification of Thyroid Nodules

Written by Li Jin Quan
General Surgery
Updated on April 19, 2025
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In the treatment of thyroid nodule calcification, we generally decide based on the size of the calcification. Usually, larger calcifications have a lower malignancy rate. Such calcifications can continue to be observed. Depending on specific circumstances, a fine needle aspiration cytology test may be chosen. Depending on the results of the pathological examination after the aspiration, we decide the next treatment approach, whether to continue observation or proceed with surgery. The second type involves smaller calcifications, which relatively have a higher malignancy rate. Our preferred treatment is surgery. During the surgery, based on the medical examination results, if the nodule is malignant, we need to further devise other treatment plans, including expanded surgery, radiotherapy, etc.

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Written by Li Jin Quan
General Surgery
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How to treat thyroid nodules calcification.

The treatment of thyroid nodule calcification in clinical practice is based on the size of the calcification lesions. Because large calcified thyroid nodules have a very small possibility of malignancy, the routine clinical approach is to continue observation and perform cytological examination through thyroid fine-needle aspiration. For small calcified thyroid nodules, which have a higher likelihood of malignancy, active surgical treatment is usually adopted. During surgery, the next steps of the treatment plan are determined based on the pathological findings.

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Written by Luo Juan
Endocrinology
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Can thyroid nodules be treated?

It depends on the situation. For some patients, we can evaluate whether thyroid nodules are accompanied by changes in thyroid function. If there is an overactive thyroid, antithyroid treatment is necessary. If there is underactive thyroid function, appropriate thyroid hormone supplementation is needed, and some patients' nodules can shrink. Additionally, for some thyroid nodules, if there are no accompanying changes in thyroid function, and the nodules are assessed as benign through ultrasound and other evaluations, no special treatment is generally needed. It is recommended to monitor thyroid ultrasound and function every six months to a year. Furthermore, if some thyroid nodules grow rapidly or there is a potential for cancerous changes, or if there are significant compressive symptoms, we can also perform a fine needle aspiration biopsy of the thyroid cells, or surgical treatment. Therefore, whether thyroid nodules can be treated also depends on the situation.

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Written by Chen Xie
Endocrinology
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The difference between thyroid enlargement and thyroid nodules

Thyroid enlargement generally refers to simple thyroid enlargement, which is typically diffuse thyroid enlargement, mainly caused by iodine deficiency, commonly seen in endemic goiter and physiological thyroid enlargement. Thyroid nodules, on the other hand, are nodular hyperplasia of the thyroid caused by certain physical and chemical factors. Thyroid nodules can manifest as benign hyperplasia or malignant hyperplasia. Therefore, the risks associated with thyroid nodules are relatively greater than those of thyroid enlargement. However, some patients with thyroid enlargement, as the disease progresses, can develop nodular hyperplasia of the thyroid. These are the differences between the two.

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Written by Hu Jian Zhuo
Nephrology and Endocrinology
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Do thyroid nodules affect pregnancy?

This decision should be based on the nature of the thyroid nodules. If the thyroid nodule is benign, pregnancy generally will not be affected, and it is possible to conceive. However, if the patient has malignant thyroid nodules, I would advise against rushing into pregnancy. Firstly, prioritize treating the malignant thyroid nodules promptly. If you become pregnant during this time, the risks associated with surgery and medications for both the pregnant mother and the fetus are very high. Nevertheless, after receiving timely and standardized treatment and once the patient's condition has stabilized, it is possible to conceive. However, it should be noted that surgery may lead to reduced thyroid function. In the first 12 weeks of pregnancy, the fetus relies on the mother for thyroid hormone supply. If the mother's thyroid hormone levels are too low, it can lead to delayed fetal development, and even abnormal brain development, resulting in a baby born with intellectual disabilities. Therefore, women with a history of thyroid disease should develop a treatment plan under the joint collaboration of an endocrinologist and an obstetrician-gynecologist.

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Written by Lin Xiang Dong
Endocrinology
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Where to do acupuncture for thyroid nodules?

Thyroid nodules do not require acupuncture treatment. The vast majority of thyroid nodules are benign, with only a small portion, about 5%, being malignant. We generally determine the treatment approach based on whether the nodule is benign or malignant. For benign nodules, we typically follow up with observation, while malignant nodules require surgical treatment and oral medication, or Iodine-131 radiotherapy. The primary evaluation for distinguishing between benign and malignant nodules relies on the results of color Doppler ultrasound and the pathology results from thyroid fine-needle aspiration.