Can people with systemic lupus erythematosus have children?

Written by Yang Ya Meng
Rheumatology
Updated on November 26, 2024
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Patients with systemic lupus erythematosus can have children, but only if they are taking less than one and a half steroids and less than two hydroxychloroquine tablets. Additionally, they must be closely monitored throughout the early, middle, and late stages of pregnancy, and regularly consult with both obstetricians and rheumatologists to discuss any necessary adjustments in treatment. This is because pregnancy is a high-risk factor for triggering lupus activity, with the disease often relapsing during the first six weeks of pregnancy and the six weeks following childbirth. (Medications should be used under the guidance of a physician.)

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What causes systemic lupus erythematosus?

Firstly, systemic lupus erythematosus belongs to autoimmune diseases and is a multisystemic autoimmune disorder. It is a chronic disease that cannot be cured. It can only be managed through medication to control the progression of the disease, prevent relapses, delay damage to other organs, and prevent complications. This is the overall principle of treatment. Its cause is currently unclear. It is only related to factors such as environmental pollution, viral infections, genetics, and hormones, according to expert research. However, there is no specific definitive cause identified.

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Can systemic lupus erythematosus be cured completely?

Firstly, systemic lupus erythematosus is a chronic autoimmune disease that causes damage to multiple systems. Its occurrence is associated with factors such as genetics, environmental pollution, infections, and hormone levels. As an autoimmune disease, it cannot be completely cured. Treatment involves using medications to control symptoms, delay the onset of complications, reduce disability rates, and improve quality of life. This represents the comprehensive goals of its treatment. The first choice of treatment is corticosteroids. Once diagnosed with systemic lupus erythematosus, it is essential to conduct thorough examinations to assess the activity of the disease and the organs involved. Based on the activity of the disease and the organs affected, the dosage of treatment may vary.

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Typical skin manifestations of systemic lupus erythematosus

The most typical skin rashes of systemic lupus erythematosus are called butterfly rash and discoid rash. The so-called butterfly rash is a rash on both sides of the nostrils, resembling the wings of a butterfly, and the so-called discoid rash is a circular, disc-shaped rash on the facial area. At the same time, patients with systemic lupus erythematosus may also experience reticular purpura or vasculitic rashes like those of end-finger vasculitis, all of which are typical manifestations of skin rashes in patients with systemic lupus erythematosus.

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Systemic Lupus Erythematosus Symptom Chart

Firstly, systemic lupus erythematosus is a multi-system, multi-organ autoimmune disease that cannot be cured but can only be controlled with medication to slow the progression of the disease and prevent complications. Clinical manifestations are diverse, with most early symptoms typically being atypical, and sometimes not presenting any discomfort at all. Some individuals may experience acute onset, which can include high fever, progressive decline in platelets, and even progressive anemia, all characteristic of the acute phase. Other common symptoms include fever, skin erythema, and even ischemia of the extremities. Some people may experience joint pain, mainly in the finger joints and knee joints, as well as swelling of the lower limbs, chest tightness, and decreased exercise tolerance, which are more typical manifestations.

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What to do about hair loss from systemic lupus erythematosus?

Systemic lupus erythematosus is a multi-system, multi-damage autoimmune disease, primarily manifesting in the skin and mucous membranes. Some individuals may also experience low-grade fever and hair loss, even severe hair loss. If treatment has already commenced and hair loss continues during the treatment process, it is necessary to consider whether the medication dosage is insufficient and to consider adjusting the medication dosage. If medication has been discontinued and severe hair loss reoccurs, the first consideration should be whether there is a recurrence of active disease, necessitating a visit to the hospital for tests including a complete blood count, erythrocyte sedimentation rate, C-reactive protein, complement levels, and autoimmune antibodies to comprehensively assess whether the disease has relapsed. If the disease has relapsed, it is necessary to reintroduce steroids, adjust medication dosages, and combine the use of hydroxychloroquine to control the disease. (Specific medications should be used under the guidance of a physician.)