Firstly, systemic lupus erythematosus is a multisystemic, systemic autoimmune disease that can involve multiple organs throughout the body. Regarding the issue of whether one with systemic lupus erythematosus can become pregnant, it cannot be generalized and must be considered in conjunction with the condition of the disease. For example, if the disease is in its early stages and has been stabilized through treatment, then it is possible to become pregnant. If systemic lupus erythematosus has already presented with severe complications, such as lupus nephritis, significant proteinuria, or an increase in creatinine urea, affecting kidney function and causing kidney damage, then it is not recommended to become pregnant during this period. Pregnancy at this time not only offers no substantial benefit to the person with systemic lupus erythematosus but can also increase the burden on the kidneys, leading to further deterioration of kidney function, which can be life-threatening.