The difference between osteoarthritis and rheumatoid arthritis

Written by Li Jie
Orthopedics
Updated on September 02, 2024
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In everyday life, many patients confuse osteoarthritis with rheumatoid arthritis, but these two diseases are indeed very distinct. Generally speaking, osteoarthritis is mostly caused by hyperplastic arthritis due to trauma or, in some cases, osteoarthritis resulting from overuse,

The characteristic of osteoarthritic pain is that it is related to activity. The more a joint affected by arthritis moves, and the greater the overuse, the more severe the pain becomes. When resting, the pain in that joint will decrease,

However, rheumatoid arthritis is different and has clear distinctions from osteoarthritis. Rheumatoid arthritis typically affects the small joints of the limbs, usually occurs symmetrically, and rarely affects only one limb. Once it occurs, it generally affects other parts too, appearing in both hands or both feet. These small joints are usually the first to be affected, with symptoms presenting symmetrically, and there is significant morning stiffness; that is, joints are stiff in the morning,

Furthermore, rheumatoid arthritis can cause pain at rest or pain during inactivity, and nocturnal pain does not necessarily correlate with activity. Sometimes, pain may intensify after rest or during the night, and sometimes, physical activity may actually alleviate the pain. Thus, this symptom is a primary distinguishing feature from osteoarthritis. Understanding these points, the differences between osteoarthritis and rheumatoid arthritis can basically be mastered.

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Written by Yang Ya Meng
Rheumatology
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What causes rheumatoid arthritis?

The causes of rheumatoid arthritis are mainly classified into four categories, First, environmental factors, such as living in dark, damp conditions for a long period, may trigger the onset of rheumatoid arthritis. Second, genetic factors, the probability of developing rheumatoid arthritis significantly increases if a parent has the condition. Third, rheumatoid arthritis often relates to estrogen, thus it is more commonly seen in female patients clinically. Fourth, rheumatoid arthritis is also associated with certain infections, including some viral and bacterial infections.

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Written by Yang Ya Meng
Rheumatology
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Rheumatoid Arthritis Diagnostic Criteria

The diagnostic criteria for rheumatoid arthritis include the following aspects: The first is symmetrical joint pain, primarily characterized by tenderness and swelling in the metacarpophalangeal joints, proximal interphalangeal joints, and both wrists. Secondly, it also includes abnormalities in inflammation markers, which comprise erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP), along with abnormalities in certain antibodies, mainly rheumatoid factor, CCP antibodies, and AKA antibodies. If the above symptoms are present, and these inflammation markers and antibodies are found to be abnormal upon blood testing, a diagnosis of rheumatoid arthritis can be made.

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Written by Li Jing
Rheumatology
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Rheumatoid arthritis commonly occurs at what age?

Rheumatoid arthritis is primarily a chronic systemic autoimmune disease characterized by pain in multiple joints throughout the body. The causes of the disease are not yet clear, but it is believed to be related to a combination of genetic, infectious, and environmental factors. The main pathological basis of the disease is synovitis. It commonly occurs in individuals aged between 35 and 50, and is more prevalent in females, with a significantly higher incidence rate in women than in men. Additionally, this disease can lead to disability and loss of work capacity. Therefore, early diagnosis and standard treatment are crucial. Once the condition stabilizes, the dosage should be gradually reduced to maintain the disease in a stable state.

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Written by Li Jie
Orthopedics
1min 36sec home-news-image

The difference between osteoarthritis and rheumatoid arthritis

In everyday life, many patients confuse osteoarthritis with rheumatoid arthritis, but these two diseases are indeed very distinct. Generally speaking, osteoarthritis is mostly caused by hyperplastic arthritis due to trauma or, in some cases, osteoarthritis resulting from overuse, The characteristic of osteoarthritic pain is that it is related to activity. The more a joint affected by arthritis moves, and the greater the overuse, the more severe the pain becomes. When resting, the pain in that joint will decrease, However, rheumatoid arthritis is different and has clear distinctions from osteoarthritis. Rheumatoid arthritis typically affects the small joints of the limbs, usually occurs symmetrically, and rarely affects only one limb. Once it occurs, it generally affects other parts too, appearing in both hands or both feet. These small joints are usually the first to be affected, with symptoms presenting symmetrically, and there is significant morning stiffness; that is, joints are stiff in the morning, Furthermore, rheumatoid arthritis can cause pain at rest or pain during inactivity, and nocturnal pain does not necessarily correlate with activity. Sometimes, pain may intensify after rest or during the night, and sometimes, physical activity may actually alleviate the pain. Thus, this symptom is a primary distinguishing feature from osteoarthritis. Understanding these points, the differences between osteoarthritis and rheumatoid arthritis can basically be mastered.

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home-news-image
Written by Li Jing
Rheumatology
39sec home-news-image

Can rheumatoid arthritis be cured?

Rheumatoid arthritis is a chronic autoimmune disease characterized by systemic damage to multiple joints with an unclear cause. Thus, it cannot be cured, meaning it cannot be completely healed. Treatment can only alleviate joint pain and morning stiffness through medication, delay the onset of complications, reduce bone damage, decrease disability rates, and improve quality of life. This is the comprehensive purpose of treatment. Therefore, early diagnosis and standardized treatment of this disease are essential to prevent joint deformities and to maintain quality of life.