The difference between osteoarthritis and rheumatoid arthritis

Written by Li Jie
Orthopedics
Updated on September 02, 2024
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In everyday life, many patients confuse osteoarthritis with rheumatoid arthritis, but these two diseases are indeed very distinct. Generally speaking, osteoarthritis is mostly caused by hyperplastic arthritis due to trauma or, in some cases, osteoarthritis resulting from overuse,

The characteristic of osteoarthritic pain is that it is related to activity. The more a joint affected by arthritis moves, and the greater the overuse, the more severe the pain becomes. When resting, the pain in that joint will decrease,

However, rheumatoid arthritis is different and has clear distinctions from osteoarthritis. Rheumatoid arthritis typically affects the small joints of the limbs, usually occurs symmetrically, and rarely affects only one limb. Once it occurs, it generally affects other parts too, appearing in both hands or both feet. These small joints are usually the first to be affected, with symptoms presenting symmetrically, and there is significant morning stiffness; that is, joints are stiff in the morning,

Furthermore, rheumatoid arthritis can cause pain at rest or pain during inactivity, and nocturnal pain does not necessarily correlate with activity. Sometimes, pain may intensify after rest or during the night, and sometimes, physical activity may actually alleviate the pain. Thus, this symptom is a primary distinguishing feature from osteoarthritis. Understanding these points, the differences between osteoarthritis and rheumatoid arthritis can basically be mastered.

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Written by Li Jing
Rheumatology
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Does rheumatoid arthritis hurt?

Firstly, rheumatoid arthritis belongs to autoimmune diseases and is a chronic condition. The main symptoms include symmetric pain in multiple joints across the body, accompanied by morning stiffness, which is why joint pain occurs and is the most common symptom. The onset is slow for most people, but some experience an acute onset, with joint mobility issues appearing within a few weeks or days. Therefore, this disease cannot be cured; it can only be managed with medications to control symptoms, delay the deformity of joints, reduce disability rates, and enhance the quality of life, which are the objectives of comprehensive treatment. It is important to avoid exposure to cold and fatigue in daily life, avoid contact with cold water, keep warm, also avoid raw and cold foods, spicy and irritating foods, and eat more light, easy-to-digest, and high-protein foods to boost the immune system.

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Written by Yang Ya Meng
Rheumatology
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What medicine is taken for rheumatoid arthritis?

The medication for rheumatoid arthritis mainly falls into three categories, The first category is the choice of anti-inflammatory and pain relief medications, which mainly includes two types: non-steroidal analgesics and low doses of corticosteroids. If the patient's pain symptoms are mild, non-steroidal analgesics can be opted for. However, if the patient's pain symptoms are more severe, and there is significant liver or kidney damage, or concurrent interstitial lung disease, then the use of low doses of corticosteroids should be considered. The second and most important category is the choice of immunosuppressants, which include drugs like methotrexate and leflunomide. The third category is the treatment with biologic agents. (Medication should be administered under the guidance of a doctor)

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Written by Yang Ya Meng
Rheumatology
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How is rheumatoid arthritis diagnosed?

Rheumatoid arthritis examinations include blood tests and imaging studies. The blood tests include complete blood count, erythrocyte sedimentation rate, rheumatoid factor, C-reactive protein, anti-streptococcal antibodies, ANA, anti-CCP antibodies, and anti-AKA antibodies. Imaging studies involve X-ray examinations of the hand joints. If the patient has significant increases in erythrocyte sedimentation rate and C-reactive protein, positive CCP and AKA antibodies, and the X-rays show bone destruction, then rheumatoid arthritis can be considered as a diagnosis.

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Written by Yang Ya Meng
Rheumatology
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The difference between osteoarthritis and rheumatoid arthritis.

Osteoarthritis is primarily a degenerative joint disease, most commonly occurring in weight-bearing joints and the distal joints of both hands. Therefore, if there is pain in the distal joints of the hands or in joints like the knee, it may be osteoarthritis. Rheumatoid arthritis mainly affects the metacarpophalangeal joints, proximal interphalangeal joints, and both wrists. It is also important to distinguish that in patients with osteoarthritis, inflammation indicators such as sedimentation rate, C-reactive protein, and endocrine factors are usually normal. However, in patients with rheumatoid arthritis, these indicators, including sedimentation rate, C-reactive protein, and rheumatoid factor, are abnormally elevated.

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Written by Li Jing
Rheumatology
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Rheumatoid arthritis symptoms

Rheumatoid arthritis is categorized as an autoimmune disease and is a chronic autoimmune condition that is destructive to joints. It is primarily characterized by symmetric polyarthritis, with clinical manifestations varying significantly among individuals. Most cases begin gradually, initially presenting with symmetrical pain and swelling in the wrists. This often accompanies morning stiffness, fatigue, low-grade fever, muscle pain, or weight loss. In a minority of cases, the onset is more abrupt, with typical clinical manifestations appearing within a few days, including joint dysfunction, morning stiffness, and joint pain and swelling. Joint deformity is a later manifestation of the disease, indicating that the disease was not well-controlled, leading to joint damage.