How to relieve ankylosing spondylitis

Written by Yang Ya Meng
Rheumatology
Updated on April 09, 2025
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Methods to alleviate ankylosing spondylitis are as follows:

First, in terms of lifestyle: during the remission phase of ankylosing spondylitis, it is necessary to persist in long-term functional exercises to keep the spine from adhering and becoming rigid.

The second and most important aspect is the long-term use of medication. The medications used to treat ankylosing spondylitis mainly include the following categories: The first category is non-steroidal anti-inflammatory drugs, commonly used ones include diclofenac sodium sustained-release tablets, celecoxib capsules, etc.; the second category includes disease-controlling medications such as sulfasalazine, thalidomide, methotrexate, and even leflunomide. Currently, the most effective medications for treating ankylosing spondylitis are biologics. However, before using biologics, it is essential to strictly rule out diseases such as hepatitis, tuberculosis, and tumors.

(Medications should be used under the guidance of a doctor based on specific conditions.)

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Symptoms of ankylosing spondylitis

The main symptom of ankylosing spondylitis is pain, characterized by pain in the lower back and lumbar region. The pain occurs during rest and diminishes with activity; it is especially severe at night, often waking the sufferer, who then finds mild activity alleviates the pain enough to return to sleep. As the disease progresses, chest pain and restricted rib cage movement begin, due to the disease spreading to the thoracic vertebrae and eventually reaching the cervical vertebrae in later stages, resulting in difficulty moving the neck. Early physical signs include tenderness in the sacroiliac joints and paraspinal muscles. X-rays can reveal that the sacroiliac joints are often the first to be affected, usually showing sacroiliitis. Additionally, there is a particularly high positivity rate for HLA-B27, the human leukocyte antigen B27, which can reach up to 90%, whereas it is typically around 4%-9% in the general population.

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Early symptoms of ankylosing spondylitis

The initial symptoms of ankylosing spondylitis mainly manifest as morning stiffness in the back. Then, there appears to be pain in the back and hip joints. The pain is generally more noticeable at night, and patients often wake up at night due to back pain. Pain can be significantly relieved after light activity. Early ankylosing spondylitis generally does not have characteristic clinical manifestations. A definitive diagnosis requires physical examinations, imaging studies, and blood tests. After confirming the diagnosis, timely and standard treatment is needed. Treatment can control the inflammation and pain of the synovium, prevent the further development of the disease, and prevent deformities of the spine and joints.

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Can ankylosing spondylitis cause red eyes?

Firstly, ankylosing spondylitis is a chronic autoimmune disease that primarily affects the axial joints. Its most common clinical manifestations are a stiffness in the neck or pain in the lumbar and back areas. This pain often occurs after sitting for a long time or at night, and symptoms are relieved after standing up and moving around; these are the main joint symptoms. In addition to these, there can also be extra-articular manifestations, with the most common being uveitis or iritis, which occur repeatedly. Some individuals may even develop corneal ulcers, also known in layman's terms as experiencing "red eye." These are extra-articular symptoms. Once recurrent uveitis or iritis occurs, aside from considering eye-related issues, systemic diseases must also be considered. Following the onset of this type of uveitis, the first choice of treatment is biologics.

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Does ankylosing spondylitis have a genetic component?

Ankylosing spondylitis is an autoimmune disease primarily affecting the axial joints. The onset is determined by both genetic and environmental factors, leading to the disease. This means that the disease exhibits a significant familial aggregation and genetic predisposition. If the parents have it, the incidence in their children is much higher than in others. However, it is definitely not a genetic disease; it just has familial clustering and genetic tendencies. If symptoms like stiffness in the neck or pain in the lower back intensify when at rest and decrease after activity, it is essential to use CT or MRI scans and test for HLA-B27 to check for damage or narrowing in the sacroiliac joints. Early diagnosis and early treatment are crucial to improve the prognosis of the condition.

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Ankylosing Spondylitis Exercise Methods

Ankylosing spondylitis is an autoimmune disease that primarily affects the axial joints and currently has no curative treatment. Its treatment includes general measures, medication, and surgery. General measures mainly involve abstaining from alcohol, quitting smoking, avoiding carbonated drinks and coffee, which can lead to osteoporosis. In addition, it is important to focus on exercise; functional exercises are a crucial part of its treatment. Regular activities such as swimming, walking, and running are recommended, and chest-expanding exercises can improve muscle rigidity. Moreover, it is advisable to sleep on a hard bed to keep the spine level. Swimming is the best form of exercise for patients with ankylosing spondylitis as it does not overload the joints while also enhancing the coordination and flexibility of the limb muscles.