Can ankylosing spondylitis cause red eyes?

Written by Li Jing
Rheumatology
Updated on May 03, 2025
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Firstly, ankylosing spondylitis is a chronic autoimmune disease that primarily affects the axial joints. Its most common clinical manifestations are a stiffness in the neck or pain in the lumbar and back areas. This pain often occurs after sitting for a long time or at night, and symptoms are relieved after standing up and moving around; these are the main joint symptoms. In addition to these, there can also be extra-articular manifestations, with the most common being uveitis or iritis, which occur repeatedly. Some individuals may even develop corneal ulcers, also known in layman's terms as experiencing "red eye." These are extra-articular symptoms. Once recurrent uveitis or iritis occurs, aside from considering eye-related issues, systemic diseases must also be considered. Following the onset of this type of uveitis, the first choice of treatment is biologics.

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Written by Li Jing
Rheumatology
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How to exercise with ankylosing spondylitis?

Once diagnosed with ankylosing spondylitis, after ruling out contraindications such as hepatitis B infection and tuberculosis, it is necessary to administer standard medications to improve rheumatic conditions. At the same time, it is necessary to develop good living habits, such as abstaining from alcohol, quitting smoking, and avoiding carbonated drinks and coffee, as these can exacerbate osteoporosis. Secondly, it is important to exercise regularly; one can walk slowly, run, or swim. Swimming is the best form of exercise for patients with ankylosing spondylitis as it can enhance the coordination of limb muscles while also delaying joint wear. Thirdly, it is important to maintain good posture and sleep on a hard bed.

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Written by Li Jing
Rheumatology
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Can people with ankylosing spondylitis work out?

Ankylosing spondylitis is an autoimmune disease that cannot be cured. It can only be managed with medication to control the condition, delay the onset of joint deformities, and reduce the rate of disability. Lifestyle changes are also a part of the treatment, including quitting smoking and drinking, and avoiding carbonated beverages as they can exacerbate bone loss. Additionally, regular exercise is important, with swimming being the best option. Swimming not only exercises the limbs and improves muscle coordination but also reduces joint wear and tear, making it the ideal form of exercise. For patients who cannot swim, other forms of exercise such as walking or running are also beneficial for fitness.

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Written by Yang Ya Meng
Rheumatology
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What tests are done for ankylosing spondylitis?

The main laboratory indicators for ankylosing spondylitis include the following: Testing for the B27 gene, formally known as HLA-B27 gene, which is hereditary and commonly found in male patients. Second, to determine if ankylosing spondylitis is in an active phase, inflammatory markers such as erythrocyte sedimentation rate and C-reactive protein can be checked. Moreover, the diagnosis of ankylosing spondylitis must involve the sacroiliac joints being affected. Therefore, a CT scan and MRI of the sacroiliac joints can be conducted to determine if there are issues with the sacroiliac joints. If the patient shows symptoms of inflammatory lower back pain, has affected sacroiliac joints, tests positive for the B27 gene, and shows elevated inflammatory markers, then a diagnosis of ankylosing spondylitis can generally be confirmed.

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Written by Li Jing
Rheumatology
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How is ankylosing spondylitis diagnosed?

Ankylosing spondylitis is an autoimmune disease that cannot be cured but can be managed primarily through medication. Its main typical symptoms include stiffness in the neck or pain in the lower back, with the pain becoming more apparent when at rest or after sitting for a long time. Symptoms tend to improve with movement. A typical occurrence is pain that awakens the patient at night. Peripheral joints like the knee joint and heel can also be affected. However, the main symptoms are stiffness in the neck and pain in the lower back. Diagnosing ankylosing spondylitis requires combining symptoms with a positive B27 blood test result, and imaging tests such as CT or MRI of the sacroiliac joints, showing signs of sacroiliitis, narrowing or damage in the sacroiliac joint space, to confirm the diagnosis.

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Written by Li Jing
Rheumatology
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Does ankylosing spondylitis cause buttock pain?

Ankylosing spondylitis may cause buttock pain. It primarily affects the axial joints, and can be accompanied by extrarticular manifestations. This condition leads to stiffening and deformity of the spine, and it cannot be cured, only managed with medication to slow the progression of the disease, delay joint deformity, improve quality of life, and reduce disability rates. Its clinical manifestations vary widely, and its onset is often insidious. Men are more commonly affected and tend to experience more severe symptoms. The most common symptoms include stiffness in the neck or pain in the lumbar and back areas. However, some people may experience pain in the lower back, accompanied by morning stiffness, or alternating pain in the buttocks, or radiating pain from the groin to the lower limbs. This pain is often worse at night or after prolonged sitting, but symptoms can lessen after activity.