What should I do in the late stage of ankylosing spondylitis?

Written by Li Jing
Rheumatology
Updated on August 31, 2024
00:00
00:00

Firstly, ankylosing spondylitis is an autoimmune disease primarily affecting the axial joints, but it can also present with extra-articular manifestations. Severe cases can lead to ankylosis and deformities of the spine, which are complications of late-stage ankylosing spondylitis. At this stage, surgery is needed to manage the activity of the disease. If the activity of the disease is not controlled, even joint replacement can still lead to the progression of the disease and further damage to the joint structures. For severe disabling deformities, spinal orthopedic surgery can be considered, and spinal surgery is required when an acute fracture occurs.

Other Voices

doctor image
home-news-image
Written by Li Jing
Rheumatology
1min 6sec home-news-image

Can ankylosing spondylitis cause red eyes?

Firstly, ankylosing spondylitis is a chronic autoimmune disease that primarily affects the axial joints. Its most common clinical manifestations are a stiffness in the neck or pain in the lumbar and back areas. This pain often occurs after sitting for a long time or at night, and symptoms are relieved after standing up and moving around; these are the main joint symptoms. In addition to these, there can also be extra-articular manifestations, with the most common being uveitis or iritis, which occur repeatedly. Some individuals may even develop corneal ulcers, also known in layman's terms as experiencing "red eye." These are extra-articular symptoms. Once recurrent uveitis or iritis occurs, aside from considering eye-related issues, systemic diseases must also be considered. Following the onset of this type of uveitis, the first choice of treatment is biologics.

doctor image
home-news-image
Written by Guan Jing Tao
Orthopedics
37sec home-news-image

How to exercise with ankylosing spondylitis

In the early stages of ankylosing spondylitis, when the impact on the sacral and other joints is minimal, normal activities such as swimming and jogging are acceptable. However, in the later stages of ankylosing spondylitis, as the disease progressively affects the sacral, hip, and knee joints, it becomes necessary to adjust the exercise regimen, mainly focusing on walking. It is important to avoid localized exposure to the cold and to take oral medications that nourish the joint cartilage. Daily local heat therapy for the joints or appropriate acupuncture can also help to some extent in delaying the erosion and damage of the joints by ankylosing spondylitis.

doctor image
home-news-image
Written by Yang Ya Meng
Rheumatology
1min 7sec home-news-image

How is ankylosing spondylitis treated?

The treatment of ankylosing spondylitis mainly consists of three parts: The first part is anti-inflammatory and pain relief. For anti-inflammatory pain relief, non-steroidal pain relief medications are commonly chosen, such as slow-release diclofenac sodium tablets and celecoxib capsules. The second part involves the selection of medications to control the disease. Common drugs used to control the condition include sulfasalazine, thalidomide, and methotrexate tablets. The third part includes the most effective, yet most expensive, treatment option: biological agents. Common biological agents used are tumor necrosis factor antagonists. However, before using biological agents, strict screening for diseases such as hepatitis, tuberculosis, and cancer is required. Only after excluding these conditions can the treatment with biological agents be considered.

doctor image
home-news-image
Written by Li Jing
Rheumatology
1min 14sec home-news-image

Ankylosing Spondylitis Test Items

Ankylosing spondylitis is a systemic disease of unknown cause, primarily characterized by chronic inflammation of the axial joints. It mainly affects the sacroiliac joints and leads to bony ankylosis, predominantly occurring in males, especially young males. The disease has a significant familial genetic tendency. The main symptoms are pain or discomfort in the lower back and back, typically occurring at night, accompanied by difficulty turning over. Stiffness is evident in the morning or after sitting for a long time, but symptoms may alleviate after physical activity. In young and middle-aged males showing these symptoms, ankylosing spondylitis should be suspected first. The main diagnostic methods include blood tests for HLA-B27, and imaging such as CT or MRI of the sacroiliac joints to detect any sacroiliitis. Diagnosis primarily relies on the combination of symptoms, HLA-B27 results, and sacroiliac joint CT findings.

doctor image
home-news-image
Written by Yang Ya Meng
Rheumatology
1min 1sec home-news-image

How is ankylosing spondylitis treated?

The treatment of ankylosing spondylitis mainly consists of three types: The first is anti-inflammatory pain relief, primarily using non-steroidal pain relief medications, such as sustained-release diclofenac sodium tablets. The second is the selection of disease control medications, mainly involving drugs like sulfasalazine tablets. For ankylosing spondylitis, the most effective and economically expensive treatment is biological agents therapy. We commonly use drugs such as tumor necrosis factor antagonists. Patients with ankylosing spondylitis during acute pain periods are advised not to engage in intense exercise. However, during remission periods, appropriate functional exercises are recommended to prevent the adhesion and stiffness of spinal joints.