How is epilepsy caused?

Written by Liu Shi Xiang
Neurology
Updated on March 28, 2025
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Epilepsy is generally caused by cerebrovascular diseases, brain trauma, intracranial tumors, and central nervous system infections, and some cases of epilepsy are due to congenital genetic factors. Patients with epilepsy need to undergo timely examinations and treatments in the department of neurology. Examination methods mainly include CT, MRI, EEG, transcranial Doppler ultrasonography, cerebral angiography, etc., among which video EEG or ambulatory EEG is the most important basis for diagnosing epilepsy. Once epilepsy is diagnosed, the treatment plan needs to be decided based on the individual condition of the patient. If it is the patient's first episode, medication may not be necessary initially, and regular follow-ups are sufficient. However, if the patient frequently experiences episodes, it is necessary to promptly administer antiepileptic drugs, commonly used drugs include carbamazepine, oxcarbazepine, gabapentin, levetiracetam, etc.

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Written by Liu Shi Xiang
Neurology
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What causes epilepsy in children?

The causes of epilepsy in children primarily include congenital factors and acquired factors. Congenital factors are mainly due to premature birth, difficult labor, umbilical cord around the neck, neonatal intracranial hemorrhage, drug factors, etc. Acquired factors mainly include brain trauma, central nervous system infections, cerebrovascular disease, intracranial tumors, and other causes. Therefore, when a child exhibits symptoms of epilepsy, it is necessary to promptly visit the department of neurology to conduct relevant examinations to determine the cause. The examination methods mainly include CT, MRI, EEG, cerebrospinal fluid analysis, etc. After identifying the cause, symptomatic treatment methods should be adopted to control the symptoms of epilepsy episodes. In clinical practice, controlling epilepsy is mainly achieved through drug treatment, with commonly used medications including carbamazepine, sodium valproate, gabapentin, etc. For some patients with refractory epilepsy, surgical treatments may also be used to control symptoms.

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Written by Yan Xin Liang
Pediatrics
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What is childhood epilepsy?

Epilepsy is a persistent brain disease characterized by recurrent epileptic seizures, abnormal perceptions, and associated neurological, cognitive, psychological, and social issues. An epileptic seizure refers to sudden, brief symptoms and signs caused by excessive and abnormal discharges of brain neurons. Depending on the affected brain functional areas, clinical manifestations can vary, including disturbances in consciousness, motor functions, sensory abnormalities, as well as psychiatric and autonomic nervous system dysfunctions. It is important to note that epileptic seizures and epilepsy are two distinct concepts.

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Written by Liu Shi Xiang
Neurology
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What to do if epilepsy occurs multiple times?

If epilepsy occurs multiple times, it is necessary to control the patient's seizures with effective medication. For example, patients with grand mal seizures need to be given diazepam and phenobarbital in a timely manner to stop the seizures. In addition, patients also need to take long-term oral medications such as lamotrigine and sodium valproate to prevent the occurrence of epilepsy. If it is a partial seizure, patients need to take medications such as carbamazepine, oxcarbazepine, gabapentin, and pregabalin long-term to prevent seizures. For patients with intractable epilepsy that responds poorly to medication, surgical treatment can also be used to control the symptoms of epilepsy. Moreover, in their daily lives, patients need to adopt good dietary and lifestyle habits to avoid various triggers that may cause repeated seizures. For instance, patients need to ensure sufficient and good quality sleep, maintain a calm mindset, and also abstain from smoking and drinking. Only by doing so can the repeated occurrences of epilepsy be effectively prevented.

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Written by Tang Bo
Neurology
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What causes epilepsy relapses?

Epilepsy is a clinical syndrome caused by highly synchronized abnormal discharges of brain neurons due to various reasons. Clinically, it is characterized by episodic, transient, repetitive, and stereotyped manifestations, making recurrence a characteristic of the disease itself. The location of the neurons with abnormal discharges and the range of the abnormal discharge waves vary, leading to different forms of seizure symptoms in patients. These can manifest in various ways, including sensory, motor, consciousness, psychiatric, behavioral, and autonomic nervous system dysfunctions, and may occur simultaneously. Each seizure and each type of seizure process is referred to as an epileptic seizure. Of course, a patient can experience one or several types of epileptic seizures, thus, recurrence is a characteristic of epilepsy itself.

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Written by Tang Bo
Neurology
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What are the clinical manifestations of epilepsy?

Epilepsy is caused by abnormal discharges of brain cells, and the symptoms and clinical manifestations vary depending on the area of discharge. Main symptoms can include sudden loss of consciousness, rigidity followed by clonic convulsions, and may also involve cyanosis or purpling of the face, tongue biting, frothing at the mouth, urinary incontinence, dilated pupils, continuing for several seconds to minutes before stopping. This condition is called a generalized tonic-clonic seizure. Some patients may also experience sudden brief loss of consciousness and interruption of ongoing actions, with a blank stare and unresponsive to calls. They may perform simple automatic actions like swallowing or chewing. Generally, there is no falling, and the patient has no memory of the episode afterwards. This type of seizure is known as an absence seizure. Additionally, some may experience rigidity and clonic convulsions in one limb or a localized area, etc.