What is childhood epilepsy?

Written by Yan Xin Liang
Pediatrics
Updated on September 04, 2024
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Epilepsy is a persistent brain disease characterized by recurrent epileptic seizures, abnormal perceptions, and associated neurological, cognitive, psychological, and social issues. An epileptic seizure refers to sudden, brief symptoms and signs caused by excessive and abnormal discharges of brain neurons. Depending on the affected brain functional areas, clinical manifestations can vary, including disturbances in consciousness, motor functions, sensory abnormalities, as well as psychiatric and autonomic nervous system dysfunctions. It is important to note that epileptic seizures and epilepsy are two distinct concepts.

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Written by Tang Bo
Neurology
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What is epilepsy?

Epilepsy is a common disease in neurology and includes many types, generally including primary epilepsy and secondary epilepsy. Primary epilepsy refers to cases where the cause is unknown, while secondary epilepsy has a clear cause. Common causes include developmental disorders of the cerebral cortex, tumors, and cerebrovascular diseases, traumatic brain injuries, and central nervous system infections, including encephalitis, meningitis. Cerebrovascular diseases such as cerebral hemorrhage and cerebral infarction can also induce epilepsy. Additionally, certain neurodegenerative diseases, such as motor neuron disease and late-stage Parkinson's disease can also trigger epileptic seizures. Patients with ischemic hypoxic encephalopathy and toxic encephalopathy may also experience epileptic seizures, and some systemic diseases may also lead to epileptic seizures.

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Written by Tang Bo
Neurology
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What are the clinical manifestations of epilepsy?

Epilepsy is caused by abnormal discharges of brain cells, and the symptoms and clinical manifestations vary depending on the area of discharge. Main symptoms can include sudden loss of consciousness, rigidity followed by clonic convulsions, and may also involve cyanosis or purpling of the face, tongue biting, frothing at the mouth, urinary incontinence, dilated pupils, continuing for several seconds to minutes before stopping. This condition is called a generalized tonic-clonic seizure. Some patients may also experience sudden brief loss of consciousness and interruption of ongoing actions, with a blank stare and unresponsive to calls. They may perform simple automatic actions like swallowing or chewing. Generally, there is no falling, and the patient has no memory of the episode afterwards. This type of seizure is known as an absence seizure. Additionally, some may experience rigidity and clonic convulsions in one limb or a localized area, etc.

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Neurology
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How is epilepsy treated?

Epilepsy treatment can be divided into the following aspects: First is etiological treatment. If epilepsy is caused by tumors or cerebrovascular diseases, surgical removal of the lesion can relieve epilepsy, but seizures often still occur, so medication must not be stopped. Secondly, pharmacological treatment is necessary for epilepsy induced by unclear causes or genetic metabolic diseases. Treatment involves taking and adjusting medications under medical guidance, based on different types of seizures and individual patient circumstances. Additionally, for some cases where the cause cannot be clearly identified and no epileptic foci are found, functional surgery can be performed for treatment.

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Written by Li Jiao Yan
Neonatology
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incidence of epilepsy in children

Epilepsy is a common neurological disorder, with the highest incidence in children under the age of one. The prevalence of epilepsy in China ranges from 0.4% to 0.7%, with nine million epilepsy patients, of which six million have active epilepsy. Every day, there are 400,000 new cases of epilepsy, with a prevalence of up to 1% among those aged sixteen and under. There are many children with epilepsy, experiencing various types of seizures, each with its own characteristics, but all share the features of sudden onset, abrupt cessation, and periodicity.

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Best treatment time for childhood epilepsy

The best time to treat pediatric epilepsy is as early as possible; the earlier the child's condition is discovered, the better the treatment outcome will be. Especially when the child has their first seizure, such as with febrile convulsions or afebrile convulsions, if epilepsy appears for the first time, it is crucial to promptly check the child with a head CT scan or MRI and an electroencephalogram (EEG). If a specific cause is identified, treatment should be tailored to the child's specific condition. It is essential to bring the child to the hospital for a thorough examination as soon as possible, ensure a timely diagnosis, and administer medications promptly, as this is critically important for the child's future prognosis.