What is childhood epilepsy?

Written by Yan Xin Liang
Pediatrics
Updated on September 04, 2024
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Epilepsy is a persistent brain disease characterized by recurrent epileptic seizures, abnormal perceptions, and associated neurological, cognitive, psychological, and social issues. An epileptic seizure refers to sudden, brief symptoms and signs caused by excessive and abnormal discharges of brain neurons. Depending on the affected brain functional areas, clinical manifestations can vary, including disturbances in consciousness, motor functions, sensory abnormalities, as well as psychiatric and autonomic nervous system dysfunctions. It is important to note that epileptic seizures and epilepsy are two distinct concepts.

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Written by Liu Shi Xiang
Neurology
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What causes epilepsy in children?

The causes of epilepsy in children primarily include congenital factors and acquired factors. Congenital factors are mainly due to premature birth, difficult labor, umbilical cord around the neck, neonatal intracranial hemorrhage, drug factors, etc. Acquired factors mainly include brain trauma, central nervous system infections, cerebrovascular disease, intracranial tumors, and other causes. Therefore, when a child exhibits symptoms of epilepsy, it is necessary to promptly visit the department of neurology to conduct relevant examinations to determine the cause. The examination methods mainly include CT, MRI, EEG, cerebrospinal fluid analysis, etc. After identifying the cause, symptomatic treatment methods should be adopted to control the symptoms of epilepsy episodes. In clinical practice, controlling epilepsy is mainly achieved through drug treatment, with commonly used medications including carbamazepine, sodium valproate, gabapentin, etc. For some patients with refractory epilepsy, surgical treatments may also be used to control symptoms.

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Written by Tang Bo
Neurology
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What is epilepsy?

Epilepsy is a common disease in neurology and includes many types, generally including primary epilepsy and secondary epilepsy. Primary epilepsy refers to cases where the cause is unknown, while secondary epilepsy has a clear cause. Common causes include developmental disorders of the cerebral cortex, tumors, and cerebrovascular diseases, traumatic brain injuries, and central nervous system infections, including encephalitis, meningitis. Cerebrovascular diseases such as cerebral hemorrhage and cerebral infarction can also induce epilepsy. Additionally, certain neurodegenerative diseases, such as motor neuron disease and late-stage Parkinson's disease can also trigger epileptic seizures. Patients with ischemic hypoxic encephalopathy and toxic encephalopathy may also experience epileptic seizures, and some systemic diseases may also lead to epileptic seizures.

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Written by Yan Xin Liang
Pediatrics
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What are the symptoms of epilepsy in children?

The typical symptoms of childhood epilepsy include sudden loss of consciousness, followed initially by tonic and then clonic convulsions, often accompanied by screaming, cyanotic facial complexion, frothing or bleeding at the mouth, dilated pupils, generally lasting 40 seconds or up to 15 minutes. The convulsive seizure stops naturally, followed by a state of coma. Of course, some affected children also display varying degrees of consciousness disorders, evident disruptions in thinking, perception, emotion, and psychomotor functions, and may show signs of conditions like somnambulism and noctambulism, among other automatisms.

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Written by Liu Shi Xiang
Neurology
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What causes epilepsy?

The causes of epilepsy mainly include some congenital factors, such as pathological changes during pregnancy or childbirth, which can lead to the occurrence of epilepsy in children. In adults, epilepsy is generally secondary to severe head trauma, cerebrovascular disease, intracranial tumors, encephalitis, etc. Therefore, for patients with epilepsy, it is first necessary to actively remove various inducements and then to treat according to the type of epileptic seizures. Epilepsy mainly includes generalized seizures and partial seizures. Patients with generalized epileptic seizures can take medications such as sodium valproate and diazepam for treatment. Patients with partial epileptic seizures can take medications such as carbamazepine, oxcarbazepine, gabapentin, and levetiracetam for treatment. Generally, the symptoms of epilepsy can be effectively controlled after patients follow a standardized medication treatment regimen.

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Written by Zhang Hui
Neurology
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What medicine should not be taken for epilepsy?

Patients with epilepsy mainly rely on some internal medicine drugs for treatment. There are many drugs available today, many of which can effectively control the occurrence of epilepsy and improve the quality of life of the patients. However, it is also important to note that some drugs should not be taken in reduced quantities, Firstly, there are some drugs that affect the liver. Many drugs can impact the liver, and since many antiepileptic drugs are metabolized through the liver, combining them can increase the burden on the liver and even induce necrotic hepatitis, Secondly, it is necessary to choose the medication according to the type of epileptic seizures. For example, if it is a visual seizure, or a myoclonic seizure, then one should not take Phenytoin sodium and Carbamazepine, as these two drugs can potentially exacerbate myoclonic and visual seizures, Thirdly, patients with epilepsy should also avoid taking drugs that affect the metabolism of epilepsy medication. If used together, it can cause a reduction in the efficacy of the epilepsy drugs, easily triggering an epileptic attack, or even a prolonged state of epilepsy.