What is childhood epilepsy?

Written by Yan Xin Liang
Pediatrics
Updated on September 04, 2024
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Epilepsy is a persistent brain disease characterized by recurrent epileptic seizures, abnormal perceptions, and associated neurological, cognitive, psychological, and social issues. An epileptic seizure refers to sudden, brief symptoms and signs caused by excessive and abnormal discharges of brain neurons. Depending on the affected brain functional areas, clinical manifestations can vary, including disturbances in consciousness, motor functions, sensory abnormalities, as well as psychiatric and autonomic nervous system dysfunctions. It is important to note that epileptic seizures and epilepsy are two distinct concepts.

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Written by Tong Peng
Pediatrics
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What causes benign epilepsy in children?

There are multiple causes of benign epilepsy in children, with significant genetic factors often involved. It generally occurs during a specific developmental period in childhood due to localized diseases, and the prognosis is usually good. Such seizures in children may be caused by conditions like tuberous sclerosis, cerebral trigeminal angioma, and neurofibromatosis. Intracranial infections, such as viral encephalitis, bacterial meningitis, and tubercular meningitis, can also trigger benign epilepsy in children. Therefore, once diagnosed, early intervention treatments should be initiated to prevent the symptoms from worsening. Regular follow-ups with electroencephalograms are also necessary to understand the effects of epilepsy medications and treatments.

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Written by Tang Li Li
Neurology
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What causes epilepsy in the elderly?

If a patient has no history of epilepsy but begins to experience epileptic seizures in old age, it is generally secondary epilepsy, also known as symptomatic epilepsy. All patients should have a clear cause, but with current diagnostic techniques, it is not always possible to find the cause. If the cause cannot be identified, it is called cryptogenic epilepsy. In such cases, it is generally necessary to improve diagnostic methods, such as cranial magnetic resonance imaging (MRI) and cranial magnetic resonance angiography. The most common causes of epilepsy in the elderly are generally cerebrovascular disease, brain trauma, or encephalitis, and in some cases, brain tumors. Any disease that causes brain cell damage can potentially cause symptomatic epileptic seizures. If all imaging examinations fail to reveal any abnormalities, regular follow-ups are necessary to monitor for early-stage tumors that may not be detectable on imaging tests. Meanwhile, antiepileptic treatment should be administered, and routine blood tests, liver, and kidney functions should be regularly monitored.

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Written by Shi De Quan
Neurology
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What is an effective treatment for epilepsy?

To effectively treat epilepsy, it is crucial to adhere to the principles of medication use and cessation. First, epilepsy medication should generally be administered for one to two years without seizures before gradually reducing the dose. If seizures reoccur after dose reduction, or if there is significant worsening on electroencephalography (EEG), the dosage should be restored. If switching medications, take both medications concurrently for about a week, then gradually reduce the original medication to cessation while increasing the new medication to an effective dose. These are the principles of medication exchange and use. Then, consider the principles for attempting medication cessation. Generally, medication should not be ceased any earlier than one year and abrupt cessation should be avoided to prevent epilepticus status. If there is clear organic brain disease, persistent positive neurological signs, or continuous mental disorders with abnormal EEG readings, lifelong medication may be necessary. Some suggest that individuals older than 30 should be cautious about stopping medication. Since the recurrence rate upon cessation can exceed 50%, lifelong medication may be necessary.

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Written by Tang Bo
Neurology
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What are the clinical manifestations of epilepsy?

Epilepsy is caused by abnormal discharges of brain cells, and the symptoms and clinical manifestations vary depending on the area of discharge. Main symptoms can include sudden loss of consciousness, rigidity followed by clonic convulsions, and may also involve cyanosis or purpling of the face, tongue biting, frothing at the mouth, urinary incontinence, dilated pupils, continuing for several seconds to minutes before stopping. This condition is called a generalized tonic-clonic seizure. Some patients may also experience sudden brief loss of consciousness and interruption of ongoing actions, with a blank stare and unresponsive to calls. They may perform simple automatic actions like swallowing or chewing. Generally, there is no falling, and the patient has no memory of the episode afterwards. This type of seizure is known as an absence seizure. Additionally, some may experience rigidity and clonic convulsions in one limb or a localized area, etc.

doctor image
home-news-image
Written by Yan Xin Liang
Pediatrics
41sec home-news-image

What is childhood epilepsy?

Epilepsy is a persistent brain disease characterized by recurrent epileptic seizures, abnormal perceptions, and associated neurological, cognitive, psychological, and social issues. An epileptic seizure refers to sudden, brief symptoms and signs caused by excessive and abnormal discharges of brain neurons. Depending on the affected brain functional areas, clinical manifestations can vary, including disturbances in consciousness, motor functions, sensory abnormalities, as well as psychiatric and autonomic nervous system dysfunctions. It is important to note that epileptic seizures and epilepsy are two distinct concepts.