Difference between early-stage and mid-stage gallbladder cancer

Written by Liu Wu Cai
Hepatobiliary Surgery
Updated on December 01, 2024
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For gallbladder cancer, its staging is mainly based on the size of the tumor and whether there are metastases to other parts of the body, including lymph node metastases. In early-stage gallbladder cancer patients, the tumor is generally small and there are no metastases to other parts of the body. At this stage, patients typically do not show specific symptoms.

Additionally, for patients with mid-stage gallbladder cancer, they may experience discomfort or dull pain in the upper right abdomen, and may also experience weight loss, possibly even developing cachexia. Therefore, gallbladder cancer patients can undergo surgical removal and a pathological examination can provide a better assessment of the pathological stage, leading to a better treatment plan.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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The difference between gallbladder polyps and gallbladder cancer in ultrasound examinations

For gallbladder polyps, they are a type of benign tumor, so under color ultrasound, benign protrusions can be observed, and there are no adhesions with surrounding tissues, nor is there obvious blood vessel supply. For gallbladder cancer, it is a type of malignant tumor, so at this time, adhesions with surrounding tissues can be observed under color ultrasound, and there is obvious blood vessel supply. Therefore, for patients with gallbladder polyps and gallbladder cancer, their treatment methods are completely different, and attention should be paid. If it is a gallbladder polyp, patients generally do not exhibit obvious symptoms and do not require special management. For gallbladder cancer patients, however, it severely affects their quality of life and lifespan, so attention must be paid, and early surgical removal and treatment must be undertaken to achieve a cure.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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What's causing the vomiting in gallbladder cancer?

Gallbladder cancer patients, if they experience vomiting, the causes primarily include two aspects. On one hand, vomiting may occur due to obstructive jaundice caused by gallbladder cancer. At this time, the patient may experience abdominal distension and poor digestion, which could lead to nausea and vomiting. For treatment, it is advisable to perform surgery as soon as possible to achieve therapeutic effects and prevention. On the other hand, for gallbladder cancer patients, vomiting should be taken seriously as it could be a sign of metastasis to other parts of the body, such as the gastrointestinal tract or liver. Therefore, for gallbladder cancer patients, it is important to conduct comprehensive examinations to rule out metastasis to other locations. If metastasis occurs, systemic chemotherapy may be necessary to achieve better suppressive effects.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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What should I do if gallbladder cancer causes itchy skin?

Gallbladder cancer patients may experience skin itching, as they often develop secondary obstructive jaundice. This can lead to lighter stool color, darker urine color, yellowing of the skin and mucous membranes, and generalized itching. For treatment, surgery should be performed for better therapeutic outcomes. Although medications to reduce jaundice can be used for symptomatic treatment, surgery is generally advocated, especially for early-stage gallbladder cancer patients without significant metastasis, where early surgical removal can significantly improve prognosis. Additionally, since malignant tumors are a consumptive disease, it is advisable for patients to consume a diet high in protein, such as eggs, lean meat, and fish, to supplement the proteins needed by the body and enhance the patient's immunity.

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Written by Shen Jiang Chao
Radiology
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Gallbladder cancer CT manifestations

Gallbladder cancer commonly occurs in females, and its causes may be related to chronic and long-term irritation from cholecystitis and gallstones. On a CT scan, based on the tumor's pathological classification and growth patterns, it can be divided into the following types: The first type is the infiltrative type, which is characterized by irregular thickening of the gallbladder wall, usually greater than 1 cm, with a rough edge, and significant enhancement is seen after contrast enhancement. The second type is the mass-forming type, which presents as a large soft tissue mass filling the gallbladder, also showing significant enhancement after injection of contrast agent. The third type is the nodular type, which presents as either single or multiple nodules that protrude into the gallbladder cavity, appearing papillary or cauliflower-like. The fourth type is the obstructive type, generally a tumor at the neck of the gallbladder, causing obstruction of the common bile duct.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Is jaundice a sign of advanced gallbladder cancer?

If a patient with gallbladder cancer exhibits jaundice, it does not necessarily mean the cancer is in its late stages. As the cancer grows, it may compress the bile duct, leading to obstructive jaundice. This can result in lighter-colored stools, darker urine, and yellowing of the skin and mucous membranes, and even cause itchy skin. Therefore, it is not necessarily indicative of advanced gallbladder cancer. Of course, if a patient with late-stage gallbladder cancer experiences liver metastasis, this might also manifest as yellowing of the skin and mucous membranes throughout the body. At this point, it is necessary to carry out thorough examinations, common tests including abdominal CT scans and ultrasounds, which can better assess the condition. If metastasis is present, even systemic chemotherapy might be required to achieve a better treatment outcome.