Patients with gallbladder cancer may exhibit significantly elevated tumor markers, particularly carcinoembryonic antigen, although this is not absolute. For gallbladder cancer, its diagnosis is mainly based on clinical symptoms, physical examination, and auxiliary examinations. Early-stage gallbladder cancer generally does not have specific manifestations, but in the late stage, there can be significant right abdominal pain, localized tenderness, and rebound pain. At this time, further examinations such as CT and MRI can provide a clear diagnosis. In the blood system, that is, in blood tests, a significant increase in carcinoembryonic antigen may occur. Patients with gallbladder cancer should undergo surgical treatment as soon as possible.