How long does it take for gallstones to develop into gallbladder cancer?

Written by Liu Wu Cai
Hepatobiliary Surgery
Updated on September 04, 2024
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Gallstones do not necessarily develop into gallbladder cancer. For patients with gallstones, they mainly experience discomfort and pain in the upper right abdomen, especially after overeating or drinking alcohol, when the symptoms suddenly appear. Gallstones do not necessarily cause gallbladder cancer. If symptoms occur, surgery should be performed at this time. Only through surgery can a cure for gallbladder cancer be achieved. It is a common malignant tumor of the gallbladder, mainly caused by repeated inflammatory stimuli or genetic factors. At this time, surgery should be performed to better improve the prognosis of the patient. Early stage gallbladder cancer can be completely removed surgically to achieve a cure.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Will CA199 also be high with gallbladder cancer?

Gallbladder cancer CA199 levels are likely to be elevated. In the case of gallbladder cancer, it is a common malignant tumor of the digestive system. When tumor markers are evaluated, an increase in CA199 can be observed. For patients with gallbladder cancer, it is advisable to undergo surgical removal as early as possible to improve prognosis. Generally, early-stage gallbladder cancer patients do not show specific symptoms, and some may only experience upper abdominal bloating and discomfort, which is often overlooked. Therefore, once diagnosed with gallbladder cancer, it is usually at a mid-to-late stage. At this point, treatment can only be symptomatic and not curative, and the treatment outcome is relatively poor. However, active management is still necessary to prevent the worsening of the condition.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can people with gallbladder cancer eat lamb?

Patients with gallbladder cancer can appropriately eat mutton, as mutton is a food high in protein, which can supplement the albumin needed by the human body and better improve the patient's resistance. However, patients with gallbladder cancer may experience discomfort such as pain in the upper right abdomen and may also encounter digestive symptoms like indigestion and bloating. Therefore, it is recommended for gallbladder cancer patients to consume foods that are easy to digest, which can reduce the burden on the gastrointestinal tract and facilitate recovery. Although mutton can be consumed, it should be eaten in small, frequent meals to prevent complications such as intestinal obstruction. Additionally, for the treatment of gallbladder cancer, surgical removal should be used as early as possible to achieve a cure, with earlier detection and treatment likely leading to a relatively better prognosis.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can gallbladder cancer be detected through blood tests?

Blood tests generally cannot detect gallbladder cancer because there are no specific markers in the blood tests for gallbladder cancer. Although some tumor markers may be significantly elevated, they are not specific. Therefore, diagnosis of gallbladder cancer can be refined through abdominal CT, color ultrasound, and if necessary, puncture tissue for pathological examination to confirm the nature. Once diagnosed with gallbladder cancer, surgery should be performed as soon as possible because gallbladder cancer is a highly malignant, rapidly developing, and poor prognosis malignancy. It is important to pay attention to it and handle it promptly to improve the prognosis and potentially extend the patient’s life.

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Written by Shen Jiang Chao
Radiology
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MRI manifestations of gallbladder cancer

The manifestations of gallbladder cancer on MRI primarily include significant thickening of the gallbladder wall or a mass within the gallbladder. Generally, it appears as low signal on T1-weighted images and high signal on T2-weighted images. After enhancement, the lesion shows obvious enhancement. If the lesion is large, necrosis may occur internally. Since the gallbladder is close to the liver, if abnormal signals are found in the liver, intrahepatic metastasis should be considered, which further confirms the possibility of gallbladder cancer. Additionally, gallbladder cancer can also invade the nearby bile ducts, causing dilation of the bile ducts, as well as local or distant lymph node metastasis.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Is targeted therapy or immunotherapy better for gallbladder cancer?

The treatment of gallbladder cancer cannot be judged as whether targeted therapy or immunotherapy is better, but should be analyzed based on the specific condition of the disease. For early-stage gallbladder cancer patients, if no metastasis has occurred, the best treatment at this time is primarily surgical removal. Early-stage surgical removal can achieve a cure, and regular postoperative ultrasound checks to monitor the disease progression are sufficient. However, if the gallbladder cancer progresses to a late stage, there might be metastasis to other parts of the body, corresponding symptoms appear, and the disease progresses rapidly. The opportunity for surgical treatment may have been missed, and only systemic chemotherapy or other comprehensive treatments are available to alleviate symptoms.