What's causing the vomiting in gallbladder cancer?

Written by Liu Wu Cai
Hepatobiliary Surgery
Updated on September 01, 2024
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Gallbladder cancer patients, if they experience vomiting, the causes primarily include two aspects. On one hand, vomiting may occur due to obstructive jaundice caused by gallbladder cancer. At this time, the patient may experience abdominal distension and poor digestion, which could lead to nausea and vomiting. For treatment, it is advisable to perform surgery as soon as possible to achieve therapeutic effects and prevention. On the other hand, for gallbladder cancer patients, vomiting should be taken seriously as it could be a sign of metastasis to other parts of the body, such as the gastrointestinal tract or liver. Therefore, for gallbladder cancer patients, it is important to conduct comprehensive examinations to rule out metastasis to other locations. If metastasis occurs, systemic chemotherapy may be necessary to achieve better suppressive effects.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Can gallbladder cancer be detected through blood tests?

Blood tests generally cannot detect gallbladder cancer because there are no specific markers in the blood tests for gallbladder cancer. Although some tumor markers may be significantly elevated, they are not specific. Therefore, diagnosis of gallbladder cancer can be refined through abdominal CT, color ultrasound, and if necessary, puncture tissue for pathological examination to confirm the nature. Once diagnosed with gallbladder cancer, surgery should be performed as soon as possible because gallbladder cancer is a highly malignant, rapidly developing, and poor prognosis malignancy. It is important to pay attention to it and handle it promptly to improve the prognosis and potentially extend the patient’s life.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Will CA199 also be high with gallbladder cancer?

Gallbladder cancer CA199 levels are likely to be elevated. In the case of gallbladder cancer, it is a common malignant tumor of the digestive system. When tumor markers are evaluated, an increase in CA199 can be observed. For patients with gallbladder cancer, it is advisable to undergo surgical removal as early as possible to improve prognosis. Generally, early-stage gallbladder cancer patients do not show specific symptoms, and some may only experience upper abdominal bloating and discomfort, which is often overlooked. Therefore, once diagnosed with gallbladder cancer, it is usually at a mid-to-late stage. At this point, treatment can only be symptomatic and not curative, and the treatment outcome is relatively poor. However, active management is still necessary to prevent the worsening of the condition.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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How long does it take for gallstones to develop into gallbladder cancer?

Gallstones do not necessarily develop into gallbladder cancer. For patients with gallstones, they mainly experience discomfort and pain in the upper right abdomen, especially after overeating or drinking alcohol, when the symptoms suddenly appear. Gallstones do not necessarily cause gallbladder cancer. If symptoms occur, surgery should be performed at this time. Only through surgery can a cure for gallbladder cancer be achieved. It is a common malignant tumor of the gallbladder, mainly caused by repeated inflammatory stimuli or genetic factors. At this time, surgery should be performed to better improve the prognosis of the patient. Early stage gallbladder cancer can be completely removed surgically to achieve a cure.

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Written by Shen Jiang Chao
Radiology
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The main manifestations of gallbladder cancer on MRI

Gallbladder cancer is more common in females and is generally believed to be associated with chronic stimulation from chronic cholecystitis and gallstones. On MRI, gallbladder cancer can be categorized into several types based on case classification and growth patterns: first, the infiltrative type; second, the nodular type; third, the mass-forming type; and fourth, the obstructive type. Regardless of the pathological type of gallbladder cancer, the tumor tissue appears as a heterogeneous low signal on T1 and a heterogeneous high signal on T2. After enhancement, the tumor shows heterogeneous enhancement. If there is invasion into the liver, the boundary with liver tissue is unclear. MRI has significant advantages in assessing invasion of adjacent organs and metastasis, and can provide great value for surgery or treatment planning.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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Difference between early-stage and mid-stage gallbladder cancer

For gallbladder cancer, its staging is mainly based on the size of the tumor and whether there are metastases to other parts of the body, including lymph node metastases. In early-stage gallbladder cancer patients, the tumor is generally small and there are no metastases to other parts of the body. At this stage, patients typically do not show specific symptoms. Additionally, for patients with mid-stage gallbladder cancer, they may experience discomfort or dull pain in the upper right abdomen, and may also experience weight loss, possibly even developing cachexia. Therefore, gallbladder cancer patients can undergo surgical removal and a pathological examination can provide a better assessment of the pathological stage, leading to a better treatment plan.