Early symptoms and warning signs of gallbladder cancer.

Written by Liu Wu Cai
Hepatobiliary Surgery
Updated on September 01, 2024
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Patients with early-stage gallbladder cancer generally do not display specific symptoms or obvious precursors. Some patients may experience digestive symptoms such as abdominal bloating, indigestion, nausea, and vomiting, but these are often overlooked. Thus, by the time gallbladder cancer is diagnosed, it is usually at an advanced stage, where the pain becomes significant and is one of the main reasons patients seek medical attention.

Additionally, some patients may experience weight loss and even develop cachexia. Gallbladder cancer is a highly malignant tumor with rapid progression and a tendency to metastasize to other parts of the body, resulting in a very poor prognosis. Therefore, once diagnosed with gallbladder cancer, it is crucial to complete relevant examinations, rule out any contraindications for surgery, and proceed with surgical removal as soon as possible.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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What should I do if gallbladder cancer causes itchy skin?

Gallbladder cancer patients may experience skin itching, as they often develop secondary obstructive jaundice. This can lead to lighter stool color, darker urine color, yellowing of the skin and mucous membranes, and generalized itching. For treatment, surgery should be performed for better therapeutic outcomes. Although medications to reduce jaundice can be used for symptomatic treatment, surgery is generally advocated, especially for early-stage gallbladder cancer patients without significant metastasis, where early surgical removal can significantly improve prognosis. Additionally, since malignant tumors are a consumptive disease, it is advisable for patients to consume a diet high in protein, such as eggs, lean meat, and fish, to supplement the proteins needed by the body and enhance the patient's immunity.

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Written by Li Hu Chen
Imaging Center
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Can cholecystitis be detected by color ultrasound?

If there is gallbladder cancer, usually an ultrasonography of the liver and gallbladder or the upper abdomen can detect it. Conditions such as gallbladder cancer or liver cancer are often initially discovered and diagnosed through ultrasound. Of course, the final confirmation of diagnosis is usually achieved through pathological examination after surgery. However, in terms of initial diagnosis, it is very common to identify these conditions through ultrasound. Gallbladder cancer typically presents certain characteristic changes, such as obvious thickening of the gallbladder wall, extensive thickening including sclerosis, and significant soft tissue mass growth extending to and adhering to the liver, which are strong indicators of gallbladder cancer. Additionally, a large polyp may be seen inside the gallbladder, and surgical removal at this stage may diagnose early gallbladder cancer.

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Written by Shen Jiang Chao
Radiology
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Gallbladder cancer CT manifestations

Gallbladder cancer commonly occurs in females, and its causes may be related to chronic and long-term irritation from cholecystitis and gallstones. On a CT scan, based on the tumor's pathological classification and growth patterns, it can be divided into the following types: The first type is the infiltrative type, which is characterized by irregular thickening of the gallbladder wall, usually greater than 1 cm, with a rough edge, and significant enhancement is seen after contrast enhancement. The second type is the mass-forming type, which presents as a large soft tissue mass filling the gallbladder, also showing significant enhancement after injection of contrast agent. The third type is the nodular type, which presents as either single or multiple nodules that protrude into the gallbladder cavity, appearing papillary or cauliflower-like. The fourth type is the obstructive type, generally a tumor at the neck of the gallbladder, causing obstruction of the common bile duct.

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Written by Liu Wu Cai
Hepatobiliary Surgery
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What's causing the vomiting in gallbladder cancer?

Gallbladder cancer patients, if they experience vomiting, the causes primarily include two aspects. On one hand, vomiting may occur due to obstructive jaundice caused by gallbladder cancer. At this time, the patient may experience abdominal distension and poor digestion, which could lead to nausea and vomiting. For treatment, it is advisable to perform surgery as soon as possible to achieve therapeutic effects and prevention. On the other hand, for gallbladder cancer patients, vomiting should be taken seriously as it could be a sign of metastasis to other parts of the body, such as the gastrointestinal tract or liver. Therefore, for gallbladder cancer patients, it is important to conduct comprehensive examinations to rule out metastasis to other locations. If metastasis occurs, systemic chemotherapy may be necessary to achieve better suppressive effects.

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Written by Li Hu Chen
Imaging Center
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Can gallbladder cancer be detected by ultrasound?

If there is gallbladder cancer, we can detect it by conducting an ultrasound examination, checking the liver, gallbladder, pancreas, and spleen, or simply performing an upper abdominal ultrasound. This is because an ultrasound is typically the first choice for examining the hepato-biliary system. Why? Because it's the most convenient and quickest method. Other examinations such as CT scans or MRI often require a prior appointment, especially MRI, which may need booking days in advance. However, ultrasounds are usually done on the same day and the results are immediate, making it the preferred method for examining the liver and gallbladder. Moreover, ultrasound is quite sensitive for gallbladder cancer. It can reveal if the gallbladder wall is particularly thickened, either locally or extensively, which often suggests the presence of gallbladder cancer, or if there is a large mass of soft tissue in the area of the gallbladder fossa, which might also adhere to the surrounding liver, raising suspicions of gallbladder cancer. Additionally, if there are unusually large polyps, particularly those over 1cm or with a notably wide base, gallbladder cancer should also be considered.