Is nasopharyngeal cancer hereditary?

Written by Yao Jun
Otolaryngology - Head and Neck Surgery
Updated on September 27, 2024
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Nasopharyngeal carcinoma is a malignant tumor of the nasopharynx, primarily found in regions populated by Mongoloid races, and is particularly common in coastal areas or in Guangdong and Guangxi regions. Nasopharyngeal carcinoma has a genetic component, meaning if you have a family history of this cancer, your chances and your descendants' chances of developing nasopharyngeal carcinoma are higher compared to those without such a family history. However, having a family history does not guarantee the development of nasopharyngeal carcinoma, nor does the absence of a family history ensure one will not get it. Under such circumstances, patients with a family history should regularly check their nasopharynx and consider whether there are traces of blood in the first sputum they cough up in the morning, which might indicate a malignancy in the nasopharynx. In such cases, performing a nasopharyngoscopy can generally clarify the presence or absence of a tumor.

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Written by Deng Bang Yu
Otolaryngology
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How is nasopharyngeal carcinoma diagnosed?

Nasopharyngeal carcinoma is a malignant, occupying lesion that occurs in the nasopharyngeal area, and clinically it is mainly squamous cell carcinoma. Relatively speaking, although this tumor is malignant, its degree of malignancy is relatively low, especially when compared to liver cancer, lung cancer, and other malignant tumors. The definitive diagnosis of any tumor primarily relies on histopathological diagnosis, which means that pathological examination is the gold standard. In the case of nasopharyngeal carcinoma, we can make a pathological examination by using nasopharyngeal biopsy tissue with forceps under nasendoscopy. If cancer cells are found, then it is essentially confirmed. Of course, other examination methods, such as CT and MRI, are also helpful in diagnosing nasopharyngeal carcinoma and determining whether there are any metastases.

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Written by Deng Bang Yu
Otolaryngology
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Can late-stage nasopharyngeal carcinoma be cured?

Nasopharyngeal cancer is a malignant tumor located in the nasopharynx. Late-stage nasopharyngeal cancer refers to stages three and four, particularly stage four, where the patient experiences destruction of adjacent tissue structures and metastasis to distant organs. In such cases, clinical treatment generally involves symptomatic management or palliative care, aimed at improving the patient's quality of life and alleviating suffering. Whether nasopharyngeal cancer, especially in its late stages, can be cured is highly uncertain; its prognosis is very poor, and no one can definitively answer if it can be cured. However, the chances of cure are extremely slim, and the main approach is to provide palliative treatments.

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Written by Zhang Jun
Otolaryngology
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Can nasopharyngeal carcinoma be cured?

Nasopharyngeal carcinoma cannot be completely cured, as it is a malignant tumor, and malignant tumors cannot be completely cured worldwide. Nasopharyngeal carcinoma refers to the malignant tumors that occur at the top or lateral walls of the nasopharynx. The common clinical cause is viral infection, most commonly associated with the Epstein-Barr virus, causing dryness, pain, and itching in the nasopharynx, along with backflow, blood in sputum, and swollen lymph nodes in the neck. Patients need to undergo a detailed examination with an electronic nasopharyngoscope and a CT scan of the nasopharynx for diagnosis. If an abnormal neoplasm is found, local pathological treatment is required. Once confirmed as malignant, local radiation therapy, chemotherapy, and surgical treatment are also needed. After surgery, patients need to undergo regular follow-up examinations, and further treatment may be required if abnormal proliferation is found.

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Written by Li Rui
Otolaryngology
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How should nasopharyngeal carcinoma be examined?

Nasopharyngeal carcinoma is a relatively common otolaryngological disease and is also considered as one of the common head and neck malignant tumors. For diagnosis, an initial examination that can be conducted is nasopharyngoscopy. Through nasopharyngeal endoscopy, most patients can see changes in the nasopharynx due to new growths, which suggests considering a pathological biopsy test. This helps in obtaining a pathological diagnosis and allows for analysis and typing of the pathology. At the same time, imaging exams are necessary, with nasopharyngeal CT or MRI being commonly used. Additionally, it is recommended to test for the Epstein-Barr virus, as some patients’ condition could be a result of a long-term infection with this virus.

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Written by Deng Bang Yu
Otolaryngology
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What are the symptoms of late-stage nasopharyngeal carcinoma?

Nasopharyngeal cancer is a common malignancy in otolaryngology, primarily located in the nasopharyngeal area. In advanced stages, nasopharyngeal cancer manifests symptoms in two main aspects. One involves symptoms directly caused by the cancer or its metastasis, typically presenting as increased nasal masses, enlarged cervical lymph nodes, severe headaches, decreased hearing, and bleeding in the nasal area due to tumor cells or tissue eroding the internal carotid artery. Additionally, there is a foul smell from the nasopharyngeal area. The second aspect relates to systemic symptoms due to the growth of nasopharyngeal cancer, leading to poor overall nutritional status and cachexia, characterized by extreme emaciation. There is also the potential for distant metastasis of the tumor cells, presenting symptoms in the corresponding areas.