What should be checked first for nasopharyngeal carcinoma?

Written by Zhang Jun
Otolaryngology
Updated on April 29, 2025
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Nasopharyngeal carcinoma refers to the malignant tumors that occur in the nasopharynx. Clinically, most cases of nasopharyngeal carcinoma are due to symptoms caused by EB virus infection. Patients may experience dryness, itching, and pain in the nasal cavity, and in the morning, they may also have blood-tinged sputum and purulent secretion symptoms. In severe cases, patients may also experience symptoms such as tinnitus, ear pain, hearing loss, and ear congestion. If these symptoms occur, patients should first undergo a detailed examination with an electronic nasopharyngoscope and a CT scan of the nasopharynx to check for abnormalities. During the examination, the top of the nasopharynx may be found to be perforated, or cauliflower-like neoplasms or ulcers may be seen on the surface of the pharyngeal recesses. At this point, patients will need to undergo a local biopsy. Once confirmed as a malignant tumor, patients will need to undergo relevant radiation therapy and chemotherapy to prolong life.

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Can nasopharyngeal carcinoma be treated?

Nasopharyngeal carcinoma is a common clinical disease, especially in the southern regions of China. It primarily affects the nasal area as a malignant tumor. The clinical treatment outcomes for nasopharyngeal carcinoma are relatively good, and it is also referred to as "fortunate cancer," which implies that it has a relatively high cure rate. The main clinical treatment involves radiation therapy combined with chemotherapy, often described as the "sandwich" treatment method. Any tumor can be cured if detected early, and the early detection rate of nasopharyngeal carcinoma is relatively high. Therefore, its cure rate is also relatively high compared to other major organ tumors such as liver and lung cancers, which exhibit relatively lower cure rates and outcomes.

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Nasopharyngeal cancer examination items

Nasopharyngeal carcinoma is a relatively common type of malignant tumor in the head and neck area, with many examination procedures commonly used. Clinically, nasopharyngoscopy, magnetic resonance imaging (MRI), and pathological biopsy are frequently utilized. Nasopharyngoscopy and MRI of the nasopharyngeal area help determine the specific range of the lesion, which is useful for clinical staging and typing. However, the gold standard for diagnosing nasopharyngeal carcinoma still requires a pathological biopsy. During a nasopharyngoscopy, a sample of soft tissue can be taken for pathological analysis, which allows for a clear diagnosis as well as pathological staging and typing, aiding in subsequent treatment.

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Do people with nasopharyngeal carcinoma lose weight?

Some patients with nasopharyngeal carcinoma may experience weight loss, but individual differences exist. This is somewhat related to the condition itself as well as to the individual's resistance and their baseline physical fitness. If the condition is detected early and the clinical symptoms are not particularly obvious, most patients will not show significant weight loss, and many people may not have noticeable symptoms. If the condition is severe, and diet and nutrition are not properly managed in a timely manner, patients may experience weight loss, especially in advanced stages of the illness. This can result in a cachectic-like state, which poses greater challenges for treatment. It is necessary to seek medical attention promptly, assess the physical condition, and consider the need for radiotherapy and chemotherapy.

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Is nasopharyngeal carcinoma prone to metastasis?

Nasopharyngeal carcinoma is a relatively common type of malignant tumor in the head and neck area and is prone to metastasis. The most common metastasis site is the cervical lymph nodes. Some patients are diagnosed with nasopharyngeal carcinoma only after the discovery of cervical lymph node metastatic cancer. Additionally, some patients may experience intracranial metastasis or bone metastasis. Generally speaking, for patients with nasopharyngeal carcinoma, it is crucial to achieve early detection, early diagnosis, and early treatment. After treatment, long-term regular follow-up is necessary to help determine the presence of metastasis. Moreover, if metastasis is confirmed, comprehensive treatment should be combined.

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Can late-stage nasopharyngeal carcinoma be cured?

Nasopharyngeal cancer is a malignant tumor located in the nasopharynx. Late-stage nasopharyngeal cancer refers to stages three and four, particularly stage four, where the patient experiences destruction of adjacent tissue structures and metastasis to distant organs. In such cases, clinical treatment generally involves symptomatic management or palliative care, aimed at improving the patient's quality of life and alleviating suffering. Whether nasopharyngeal cancer, especially in its late stages, can be cured is highly uncertain; its prognosis is very poor, and no one can definitively answer if it can be cured. However, the chances of cure are extremely slim, and the main approach is to provide palliative treatments.