Is allergic purpura nephritis easy to treat?

Written by Pan Wu Shan
Nephrology
Updated on September 15, 2024
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Allergic purpura nephritis is essentially a kidney complication caused by allergic purpura. The main symptoms are that the patient first presents with scattered purple spots on the lower limbs, known as allergic purpura. Subsequently, routine urine tests reveal hematuria or proteinuria, allowing for a diagnosis of allergic purpura nephritis. It cannot be completely cured. Currently, treatment first requires complete quantification of urine protein and a renal biopsy to confirm whether it is allergic purpura nephritis and its severity. Generally, it involves the use of steroids. Typical treatment involves firstly avoiding allergens, so any substances that cause allergies should not be contacted to prevent triggering allergic purpura, and thus prevent the recurrence of purpura nephritis. Additionally, it involves adhering to a low-salt, low-fat diet, and avoiding catching colds or staying up late.

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Written by Li Jing
Rheumatology
1min 16sec home-news-image

Can allergic purpura be cured?

Allergic purpura mainly occurs in adolescents and children, often in the spring and autumn seasons, and is typically related to bacterial infections, viral infections, and allergies to medications and foods. The most common clinical symptoms include bruises on both lower limbs, bleeding, black stools, joint pain, and abdominal pain. Upon the appearance of bruises on the lower limbs, it is recommended to complete routine blood tests, erythrocyte sedimentation rate, and autoantibody tests to rule out other autoimmune diseases causing skin bruises. During the acute phase, it is necessary to rest in bed, drink plenty of water, and eat a light diet. If there are only simple skin bruises, these may resolve after rest. However, if joint pain, bloody stools, and black stools occur, formal and active treatment is required, as these symptoms will not resolve on their own. Additionally, the presence of blood or protein in urine suggests kidney involvement, indicating that the condition has worsened.

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Written by Yang Ya Meng
Rheumatology
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What medicine is taken for allergic purpura?

The medication for allergic purpura should be determined based on the severity of the patient's condition. If the patient only shows symptoms like rashes, the focus should be on reducing the rashes, and medications such as compound glycyrrhizin and desloratadine can be used for their anti-allergic effects. If the main clinical manifestation of allergic purpura is joint pain, some non-steroidal pain relief medications can be added for pain relief. However, if the patient primarily exhibits involvement of internal organs, such as gastrointestinal involvement in allergic purpura starting with abdominal pain, or kidney damage marked by significant proteinuria, then corticosteroids and immunosuppressants should be considered for treatment. (Please use medications under the guidance of a doctor).

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Written by Yang Ya Meng
Rheumatology
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Mild symptoms of allergic purpura

Allergic purpura mainly includes three pathological types. The symptoms of the mild type mainly involve changes in the skin, primarily purpura-like rashes around the lower legs and ankle joints. If there are only skin lesions, it is considered a very mild case of allergic purpura. Additionally, more severe cases may involve kidney impairment, such as the presence of protein in the urine. Some patients primarily experience joint pain, also known as the arthritic type. Another group of patients presents mainly with sudden abdominal pain, primarily known as the abdominal type. Therefore, mild symptoms of allergic purpura might just be typical rashes. As long as there is no involvement of the visceral system, it is considered relatively mild.

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Written by Yang Ya Meng
Rheumatology
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What should I do if I have allergic purpura and my legs hurt?

Patients with allergic purpura who experience leg pain indicate the development of the arthritic type of allergic purpura. Firstly, strict bed rest should be enforced in daily life to reduce the burden on the joints. Secondly, active treatment of the primary cause of allergic purpura should be pursued, which can include taking medications like desloratadine dispersible tablets to reduce the rash. Subsequently, anti-inflammatory and analgesic drugs, such as diclofenac sodium sustained-release tablets, can be taken to alleviate leg pain. If the symptoms do not significantly improve with these measures, the use of a small dose of corticosteroids may be considered if necessary. (Medication should be administered under the guidance of a professional doctor.)

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Written by Li Jing
Rheumatology
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Allergic purpura belongs to which department?

Allergic purpura is a common vasculitis related to hypersensitivity, essentially a type of vasculitis that belongs to hematological diseases. It is mostly caused by infections or allergies to food and drugs, predominantly occurring in adolescents. It is more common in males, but a minority of adults may also develop allergic purpura. The main types include abdominal, renal, articular, mixed, and cutaneous forms. However, when allergic purpura nephritis occurs, presenting with proteinuria or decreased kidney function, it is necessary to visit a nephrology department. Treatment should aim to control proteinuria, protect kidney function, and reduce damage to kidney functions. Therefore, it is essential to visit a nephrologist at this time. Allergic purpura must be differentiated in treatment; if it is merely a cutaneous or abdominal type, a hematologist can manage it. However, if the kidneys are involved, it requires consultation in a nephrology specialty. (Please use medications under the guidance of a professional physician and do not self-medicate.)