Is allergic purpura nephritis easy to treat?

Written by Pan Wu Shan
Nephrology
Updated on September 15, 2024
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Allergic purpura nephritis is essentially a kidney complication caused by allergic purpura. The main symptoms are that the patient first presents with scattered purple spots on the lower limbs, known as allergic purpura. Subsequently, routine urine tests reveal hematuria or proteinuria, allowing for a diagnosis of allergic purpura nephritis. It cannot be completely cured. Currently, treatment first requires complete quantification of urine protein and a renal biopsy to confirm whether it is allergic purpura nephritis and its severity. Generally, it involves the use of steroids. Typical treatment involves firstly avoiding allergens, so any substances that cause allergies should not be contacted to prevent triggering allergic purpura, and thus prevent the recurrence of purpura nephritis. Additionally, it involves adhering to a low-salt, low-fat diet, and avoiding catching colds or staying up late.

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Written by Li Jing
Rheumatology
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Can allergic purpura cause itching?

Allergic purpura is mainly seen in adolescents and children, with a higher incidence in spring and autumn. The most common cause is infection, followed by medications or food, which can also trigger an episode of allergic purpura. The most common symptoms include purpura on the skin and mucous membranes, abdominal pain, blood in stools, hematuria, or joint pain. The purpura primarily affects the limbs, rarely appears on the trunk, and is symmetrically distributed. At this time, the bleeding spots often have no symptoms, meaning there is no itching of the skin. However, when there is concomitant skin edema or hives, itching can occur.

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Written by Li Jing
Rheumatology
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Can allergic purpura be cured completely?

Allergic purpura is a special type of vasculitis and also a hypersensitivity disorder. It commonly occurs in adolescents and children aged 5 to 14, with a higher incidence rate in the spring and autumn seasons. The disease frequently relapses and cannot be completely cured. The most common causes of allergic purpura include infections, medications, and foods. Infections are the most frequent cause, such as bacteria, viruses, parasites, tuberculosis, etc. If it is merely a cutaneous form, no special treatment is required at this time, and bed rest alone can alleviate the condition. If there is the presence of blood or protein in the urine, and renal biopsy shows a large number of crescents, it then indicates a serious aggravation of the condition.

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Written by Zhang Peng
General Surgery
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Is allergic purpura with abdominal pain easy to treat?

Allergic purpura with abdominal pain, also known as abdominal allergic purpura, involves gastrointestinal symptoms associated with allergic purpura, primarily characterized by episodic severe abdominal pain, usually around the navel or lower abdomen, and may sometimes be accompanied by vomiting. Treatment typically involves bed rest, actively identifying the cause, controlling infections, and supplementing relevant vitamins. It's also important to check for any symptoms of gastrointestinal bleeding. If there are signs of gastrointestinal bleeding, strict dietary management is necessary, blood transfusions may be required when needed, and the healing of the gastrointestinal tract must be monitored. Medications to suppress acid or protect the gastric mucosa could be considered. Generally, the prognosis for allergic purpura is favorable, though very few severe cases may experience gastrointestinal complications such as bleeding, intussusception, or even necrosis. Although the prognosis is generally good, relapse is common. (Please use medications under the guidance of a professional physician and do not self-medicate.)

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Written by Zhou Qi
Nephrology
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Is allergic purpura nephritis contagious?

Henoch-Schönlein purpura nephritis and allergic purpura are not infectious diseases; there is no contagious element involved. Henoch-Schönlein purpura nephritis is actually kidney damage caused by allergic purpura, which is an allergic disease itself. Patients suffer from an abnormal immune response in the body’s immune system after coming into contact with allergenic drugs or foods, leading to necrotizing vasculitis. This disease is unrelated to pathogens. Generally, there is no direct damage to the kidneys caused by a specific pathogen in this disease, nor do patients carry pathogens that can cause Henoch-Schönlein purpura nephritis, such as bacteria or viruses, thus making the disease non-contagious.

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Written by Li Jing
Rheumatology
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Can allergic purpura be inherited?

Allergic purpura is mostly caused by exposure to infections, medications, or foods, leading to skin and mucous membrane ecchymoses, which are essentially petechiae and a manifestation of vasculitis. It falls under autoimmune diseases, not genetic diseases, and thus is not contagious. Bacterial, viral, mycoplasmal, or parasitic infections are the most common causes. Secondarily, medications and foods can also trigger allergic purpura, such as high-protein foods like seafood and milk. Therefore, if there are symptoms like ecchymoses on the lower extremities accompanied by joint pain, or signs of blood in the stool or black stool, it is necessary to complete routine blood tests, erythrocyte sedimentation rate, and autoimmune antibody tests to rule out other autoimmune diseases. During the acute phase, it is advisable to rest in bed, eat a light diet, avoid infection, and use corticosteroids for anti-allergy treatment if necessary.