Precursors of recurrent allergic purpura

Written by Yang Ya Meng
Rheumatology
Updated on November 12, 2024
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The precursors of a relapse of allergic purpura typically occur in patients after exposure to cold, strenuous exercise, or allergens, manifesting as purpuric rash on the skin. Additionally, some patients may experience gastrointestinal reactions such as nausea, vomiting, abdominal pain, and diarrhea. More severe cases can present with symptoms of allergic purpura and purpura nephritis, primarily characterized by edema and significant proteinuria indicated in routine urine tests. If patients experience the aforementioned symptoms, it is crucial to be vigilant about the possibility of a relapse of allergic purpura and to seek medical attention promptly to prevent further progression of the disease.

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Written by Zhou Qi
Nephrology
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Is allergic purpura nephritis contagious?

Henoch-Schönlein purpura nephritis and allergic purpura are not infectious diseases; there is no contagious element involved. Henoch-Schönlein purpura nephritis is actually kidney damage caused by allergic purpura, which is an allergic disease itself. Patients suffer from an abnormal immune response in the body’s immune system after coming into contact with allergenic drugs or foods, leading to necrotizing vasculitis. This disease is unrelated to pathogens. Generally, there is no direct damage to the kidneys caused by a specific pathogen in this disease, nor do patients carry pathogens that can cause Henoch-Schönlein purpura nephritis, such as bacteria or viruses, thus making the disease non-contagious.

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Written by Yang Ya Meng
Rheumatology
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Recurrent symptoms of allergic purpura

The clinical manifestations of recurrent allergic purpura primarily include purpuric rashes on the lower limbs. If the patient experiences joint pain, it is also a clinical symptom of recurrent allergic purpura. Some severe cases of allergic purpura may even present with abdominal pain and other gastrointestinal symptoms. Additionally, some patients may exhibit significant amounts of protein in the urine and impaired creatinine levels. This indicates allergic purpura with purpuric nephritis, which is considered severe in the context of allergic purpura. Therefore, if a patient presents with the aforementioned symptoms, the recurrence of allergic purpura should be considered. At this point, further examinations such as blood tests, urine tests, and kidney function tests can be conducted to assess the condition.

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Written by Li Jing
Rheumatology
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Is allergic purpura prone to recurrence?

First and foremost, allergic purpura refers to a hemorrhagic disease that affects the capillaries in the skin or other organs; it is categorized as a rheumatic immune disease. It primarily occurs in adolescents and children aged between five to fourteen years, and cannot be cured. The disease is prone to recurring, which is its main clinical characteristic. The primary causes are infections, drugs, or food allergies, with infections being the most significant factor. Therefore, upon the appearance of skin purpura or bleeding spots, joint swelling, or signs such as hematuria and proteinuria, timely and comprehensive examinations should be conducted for diagnosis. Once the kidneys are involved, it is essential to rest in bed until the proteinuria alleviates. Moreover, it is crucial to conduct a 24-hour urinary protein quantification to assess the extent of kidney damage. If there is a significant amount of proteinuria, it is advisable to promptly perform a renal biopsy to clarify the type of pathology.

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Written by Li Jing
Rheumatology
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Is allergic purpura serious?

Firstly, allergic purpura is caused by infections, drugs, or food allergies leading to skin ecchymosis and petechiae; in addition, it can also manifest as joint pain, hematuria, and melena. The presence of protein in a routine urine test along with hematuria or melena often indicates gastrointestinal allergic purpura and renal allergic purpura. The presence of proteinuria suggests kidney involvement, which is the most severe type among various forms of allergic purpura. If it is solely a cutaneous type, no special treatment is needed other than drinking more water and ensuring bed rest to alleviate skin ecchymosis. If proteinuria or hematuria occurs, one must rest in bed until the protein levels improve before resuming activities. Concurrently, corticosteroids and anti-allergy medications should be administered. (Medication should be used under the guidance of a professional doctor.)

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Written by Yang Ya Meng
Rheumatology
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Do you need to be hospitalized for allergic purpura?

Whether patients with allergic purpura need to be hospitalized mainly depends on the severity of their condition. For mild cases of allergic purpura, also known as purely dermal allergic purpura, where the main clinical manifestation is a rash primarily on the lower limbs, outpatient treatment is sufficient. However, if the patient has gastrointestinal or renal types of allergic purpura, hospitalization is required. The gastrointestinal type of allergic purpura involves significant symptoms such as abdominal pain and diarrhea, while the renal type is characterized by symptoms like edema and significant proteinuria. If allergic purpura affects internal organs, the digestive tract, or kidneys, hospital treatment is necessary.