How to treat allergic purpura nephritis?

Written by Li Liu Sheng
Nephrology
Updated on August 31, 2024
00:00
00:00

Kidney damage caused by allergic purpura is called allergic purpura nephritis. The main clinical manifestations include joint pain, rash, black stools, abdominal pain, as well as hematuria, increased urinary protein, elevated blood pressure, and even edema and renal insufficiency. During the acute phase of allergic purpura nephritis, patients should rest in bed, and if there is edema, intake of water and salt should be strictly restricted. It is also important to actively identify the allergens to conduct etiological treatment. Intake of certain suspected foods or medications should be prohibited. If the patient has obvious rashes and joint pain, antiallergic medications can be used for treatment. If the effect is not satisfactory, hormones and immunosuppressive agents can be introduced. Depending on the patient's condition, Traditional Chinese Medicine can also be used to invigorate blood circulation and remove blood stasis. If the condition is severe, combined treatment can be considered for better results.

Other Voices

doctor image
home-news-image
Written by Yang Ya Meng
Rheumatology
50sec home-news-image

Precursors of recurrent allergic purpura

The precursors of a relapse of allergic purpura typically occur in patients after exposure to cold, strenuous exercise, or allergens, manifesting as purpuric rash on the skin. Additionally, some patients may experience gastrointestinal reactions such as nausea, vomiting, abdominal pain, and diarrhea. More severe cases can present with symptoms of allergic purpura and purpura nephritis, primarily characterized by edema and significant proteinuria indicated in routine urine tests. If patients experience the aforementioned symptoms, it is crucial to be vigilant about the possibility of a relapse of allergic purpura and to seek medical attention promptly to prevent further progression of the disease.

doctor image
home-news-image
Written by Yang Ya Meng
Rheumatology
55sec home-news-image

Do you need to be hospitalized for allergic purpura?

Whether patients with allergic purpura need to be hospitalized mainly depends on the severity of their condition. For mild cases of allergic purpura, also known as purely dermal allergic purpura, where the main clinical manifestation is a rash primarily on the lower limbs, outpatient treatment is sufficient. However, if the patient has gastrointestinal or renal types of allergic purpura, hospitalization is required. The gastrointestinal type of allergic purpura involves significant symptoms such as abdominal pain and diarrhea, while the renal type is characterized by symptoms like edema and significant proteinuria. If allergic purpura affects internal organs, the digestive tract, or kidneys, hospital treatment is necessary.

doctor image
home-news-image
Written by Li Jing
Rheumatology
1min 2sec home-news-image

Does allergic purpura spread to others?

Firstly, allergic purpura is neither a genetic nor a contagious disease, so there is no need to worry about it being inherited or transmitted to others. It is an allergic reaction caused by drugs, food, or infections, typically manifested by bleeding and bruising on the skin and mucous membranes of the limbs, joint pain, and hematuria. Diagnosis requires the combination of clinical manifestations and related tests such as urinalysis. If it is merely a case of the skin type, it only necessitates bed rest and observation of the number and extent of bleeding points on the skin and mucous membranes without special treatment. If there are symptoms like black stools or proteinuria, bed rest is imperative along with the use of anti-allergy medications or corticosteroids to enhance treatment, continuing until the proteinuria resolves.

doctor image
home-news-image
Written by Yang Ya Meng
Rheumatology
47sec home-news-image

Symptoms of allergic purpura

Allergic purpura, which we generally divide into four types. The first type is the mildest, often primarily characterized by purpuric rash-like skin manifestations. The second type we call allergic purpura arthritis type, where patients, in addition to the typical rash, also experience joint pain symptoms. The third type we refer to as the renal type of allergic purpura, where patients often present primarily with hematuria and proteinuria, and urine tests typically indicate positive urinary protein. The fourth type we call the abdominal type of allergic purpura, where patients suffer from nausea, vomiting, abdominal pain, and diarrhea as their main clinical manifestations.

doctor image
home-news-image
Written by Li Jing
Rheumatology
1min 16sec home-news-image

Can allergic purpura be cured?

Allergic purpura mainly occurs in adolescents and children, often in the spring and autumn seasons, and is typically related to bacterial infections, viral infections, and allergies to medications and foods. The most common clinical symptoms include bruises on both lower limbs, bleeding, black stools, joint pain, and abdominal pain. Upon the appearance of bruises on the lower limbs, it is recommended to complete routine blood tests, erythrocyte sedimentation rate, and autoantibody tests to rule out other autoimmune diseases causing skin bruises. During the acute phase, it is necessary to rest in bed, drink plenty of water, and eat a light diet. If there are only simple skin bruises, these may resolve after rest. However, if joint pain, bloody stools, and black stools occur, formal and active treatment is required, as these symptoms will not resolve on their own. Additionally, the presence of blood or protein in urine suggests kidney involvement, indicating that the condition has worsened.