How to treat allergic purpura nephritis?

Written by Li Liu Sheng
Nephrology
Updated on August 31, 2024
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Kidney damage caused by allergic purpura is called allergic purpura nephritis. The main clinical manifestations include joint pain, rash, black stools, abdominal pain, as well as hematuria, increased urinary protein, elevated blood pressure, and even edema and renal insufficiency. During the acute phase of allergic purpura nephritis, patients should rest in bed, and if there is edema, intake of water and salt should be strictly restricted. It is also important to actively identify the allergens to conduct etiological treatment. Intake of certain suspected foods or medications should be prohibited. If the patient has obvious rashes and joint pain, antiallergic medications can be used for treatment. If the effect is not satisfactory, hormones and immunosuppressive agents can be introduced. Depending on the patient's condition, Traditional Chinese Medicine can also be used to invigorate blood circulation and remove blood stasis. If the condition is severe, combined treatment can be considered for better results.

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Written by Yang Ya Meng
Rheumatology
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Does allergic purpura cause vomiting?

Patients with allergic purpura may experience symptoms of vomiting. Patients with the gastrointestinal type of allergic purpura may exhibit symptoms such as vomiting, abdominal pain, and diarrhea. The gastrointestinal type is considered a severe form of allergic purpura because it affects critical internal organs and the intestines. In treatment, besides using anti-allergic methods to reduce rashes, it is also necessary to use corticosteroids to reduce inflammation and control gastrointestinal symptoms. Additionally, immunosuppressants such as mycophenolate mofetil can be used to control the gastrointestinal response. Meanwhile, patients should adhere to a strict fasting regimen until symptoms like vomiting and diarrhea improve. (Medication should be administered under the guidance of a professional doctor.)

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Written by Li Jing
Rheumatology
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What are the symptoms of allergic purpura?

The most common clinical manifestations of allergic purpura are bruises on the limbs, black stool, hematuria, and joint pain. It is mainly divided into articular, abdominal, cutaneous, renal, and mixed types. The presence of protein in the urine indicates kidney involvement, which means the condition is most severe. Allergic purpura generally can be alleviated with standard and active treatment, but recurrent attacks affecting the kidneys can lead to persistent purpuric nephritis and proteinuria that do not resolve.

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Written by Yang Ya Meng
Rheumatology
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Can people with allergic purpura eat durian?

Patients with allergic purpura should not eat durian, as durian is considered a food that can trigger allergies, which in turn can provoke the onset of allergic purpura. Besides avoiding such trigger foods in their diet, patients with allergic purpura should also avoid getting cold, as catching cold can lead to infections, which may also trigger an episode of allergic purpura. Furthermore, intense physical activity, like fast running, should be avoided as well, because such activities can also lead to outbreaks of allergic diseases. Allergic purpura is also a self-limiting disease, and can improve on its own after reaching adulthood.

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Written by Yang Ya Meng
Rheumatology
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Precursors of recurrent allergic purpura

The precursors of a relapse of allergic purpura typically occur in patients after exposure to cold, strenuous exercise, or allergens, manifesting as purpuric rash on the skin. Additionally, some patients may experience gastrointestinal reactions such as nausea, vomiting, abdominal pain, and diarrhea. More severe cases can present with symptoms of allergic purpura and purpura nephritis, primarily characterized by edema and significant proteinuria indicated in routine urine tests. If patients experience the aforementioned symptoms, it is crucial to be vigilant about the possibility of a relapse of allergic purpura and to seek medical attention promptly to prevent further progression of the disease.

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Written by Yang Ya Meng
Rheumatology
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What medicine is taken for allergic purpura?

The medication for allergic purpura should be determined based on the severity of the patient's condition. If the patient only shows symptoms like rashes, the focus should be on reducing the rashes, and medications such as compound glycyrrhizin and desloratadine can be used for their anti-allergic effects. If the main clinical manifestation of allergic purpura is joint pain, some non-steroidal pain relief medications can be added for pain relief. However, if the patient primarily exhibits involvement of internal organs, such as gastrointestinal involvement in allergic purpura starting with abdominal pain, or kidney damage marked by significant proteinuria, then corticosteroids and immunosuppressants should be considered for treatment. (Please use medications under the guidance of a doctor).