Symptoms of Allergic Purpura Nephritis

Written by Li Liu Sheng
Nephrology
Updated on July 04, 2025
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Kidney damage caused by allergic purpura is called allergic purpura nephritis. This disease is commonly seen in children. Once allergic purpura nephritis occurs, the typical clinical symptoms in patients include joint pain, recurrent rashes on both lower limbs, and abdominal pain. Of course, some patients may also experience gastrointestinal bleeding and the passing of black stools. The main clinical manifestations concerning the kidneys are hematuria and changes in urine color, which can be macroscopic or microscopic hematuria, increased urine foam, and proteinuria. Of course, some patients may also experience edema, especially noticeable swelling of the eyelids and facial area upon waking up in the morning, as well as increased blood pressure. In severe cases of allergic purpura nephritis, patients may also experience renal dysfunction and more.

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Written by Li Liu Sheng
Nephrology
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Symptoms of Allergic Purpura Nephritis

Kidney damage caused by allergic purpura is called allergic purpura nephritis. This disease is commonly seen in children. Once allergic purpura nephritis occurs, the typical clinical symptoms in patients include joint pain, recurrent rashes on both lower limbs, and abdominal pain. Of course, some patients may also experience gastrointestinal bleeding and the passing of black stools. The main clinical manifestations concerning the kidneys are hematuria and changes in urine color, which can be macroscopic or microscopic hematuria, increased urine foam, and proteinuria. Of course, some patients may also experience edema, especially noticeable swelling of the eyelids and facial area upon waking up in the morning, as well as increased blood pressure. In severe cases of allergic purpura nephritis, patients may also experience renal dysfunction and more.

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Written by Li Jing
Rheumatology
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What causes allergic purpura?

Allergic purpura commonly occurs in adolescents and children, characterized by frequent relapses and being intractable. It is primarily seen in youth aged between 5 to 14 years. As they age and their immunity strengthens, the frequency of episodes gradually decreases. The most common causes of allergic purpura include infections such as bacteria, viruses, parasites, mycoplasma infections, and allergies to medications and foods, with food allergies mainly stemming from high-protein foods like fish and shrimp, which can easily trigger allergic reactions. Therefore, once skin purpura or proteinuria appears, it is crucial to rest in bed until the pain and proteinuria dissipate and the purpura eases. During treatment, it is also important to avoid cold exposure and overexertion.

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Written by Li Jing
Rheumatology
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Is allergic purpura serious?

Firstly, allergic purpura is caused by infections, drugs, or food allergies leading to skin ecchymosis and petechiae; in addition, it can also manifest as joint pain, hematuria, and melena. The presence of protein in a routine urine test along with hematuria or melena often indicates gastrointestinal allergic purpura and renal allergic purpura. The presence of proteinuria suggests kidney involvement, which is the most severe type among various forms of allergic purpura. If it is solely a cutaneous type, no special treatment is needed other than drinking more water and ensuring bed rest to alleviate skin ecchymosis. If proteinuria or hematuria occurs, one must rest in bed until the protein levels improve before resuming activities. Concurrently, corticosteroids and anti-allergy medications should be administered. (Medication should be used under the guidance of a professional doctor.)

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Written by Yang Ya Meng
Rheumatology
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Symptoms of allergic purpura

Allergic purpura, which we generally divide into four types. The first type is the mildest, often primarily characterized by purpuric rash-like skin manifestations. The second type we call allergic purpura arthritis type, where patients, in addition to the typical rash, also experience joint pain symptoms. The third type we refer to as the renal type of allergic purpura, where patients often present primarily with hematuria and proteinuria, and urine tests typically indicate positive urinary protein. The fourth type we call the abdominal type of allergic purpura, where patients suffer from nausea, vomiting, abdominal pain, and diarrhea as their main clinical manifestations.

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Written by Yang Ya Meng
Rheumatology
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Can people with allergic purpura take baths?

Patients with allergic purpura can take baths, but the water temperature should not be too hot. This is because excessive heat or vigorous exercise can potentially trigger a recurrence of allergic purpura. Additionally, patients should avoid getting cold to reduce the risk of infection, as infections can also provoke episodes of allergic purpura. During an episode of allergic purpura, it is necessary to take some anti-allergy medications and medications that reduce rashes, such as desloratadine dispersible tablets and compound glycyrrhizin tablets. If there is significant involvement of vital organs, such as the kidneys or gastrointestinal tract, some patients may also need to use corticosteroids. (Medication should be taken under the guidance of a doctor.)