Does type 2 diabetes have a genetic component?

Written by Tang Zhuo
Endocrinology
Updated on March 29, 2025
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Diabetes has a high prevalence worldwide, especially type 2 diabetes, which accounts for over 90% of all cases. The pathogenesis of type 2 diabetes is very complex, including genetic susceptibility, as well as environmental factors, insulin resistance, and defects in the function of pancreatic beta cells. Thus, environmental factors are one of the influencing factors in the incidence of type 2 diabetes. There is evidence showing a familial clustering tendency among patients, but genetic factors are not the sole cause of type 2 diabetes; environmental factors also play a role. With changes in diet and lifestyle in recent years, the prevalence of type 2 diabetes has noticeably increased. Even with similar genetic backgrounds, the risk of developing type 2 diabetes varies among populations living in different areas. Therefore, diabetes can be considered a complex disease, where individuals with a genetic predisposition to diabetes, under the influence of adverse environmental conditions, can also develop elevated blood sugar levels and consequently diabetes.

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Written by Li Hui Zhi
Endocrinology
1min 6sec home-news-image

Type 2 diabetes daily diet

Type II diabetes requires careful daily dietary considerations. First, meals should be regular and moderate in portion; overeating is to be avoided. Second, ideally consume only three meals a day and avoid late-night snacks, which is a habit that many people have but is inadvisable. Third, the amount of carbohydrates per meal should be controlled; about 100 grams of staple food per meal is sufficient for those who perform moderate physical labor and do not engage in heavy physical activities. Fourth, sweet foods like pastries and cakes, which are high in sugar, should be completely avoided. Fifth, foods like porridge and glutinous rice, which have a high glycemic index, are not recommended. Lastly, very sweet fruits such as lychees, longans, durians, grapes, and bananas are too sugary and not suitable for consumption.

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Written by Li Hui Zhi
Endocrinology
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How is type 2 diabetes treated?

The treatment of type 2 diabetes includes the following aspects. First, dietary treatment is recommended, advising regular and quantitative meals three times a day, and avoiding late-night snacks and extra meals. Second, appropriate exercise. Third, self-monitoring of blood glucose; it is best to purchase a glucometer for home use and show the recorded blood glucose levels to the doctor during hospital visits. Fourth, diabetes education. Fifth, medication treatment, which includes oral medications and insulin therapy. It's important to visit an endocrinology specialist promptly to determine the most suitable medication under the guidance of a doctor.

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Written by Li Hui Zhi
Endocrinology
1min 2sec home-news-image

Causes of diabetic foot

The main causes of diabetic foot are as follows: The first one is poor blood sugar control in patients. Some patients have long neglected their blood sugar levels, leading to consistently high levels. The second cause is vascular disease in the lower limbs of the patient, including arteriosclerosis, with severe cases leading to occlusion and subsequent ulceration of the feet. The third reason is the presence of diabetic peripheral neuropathy in patients, which results in abnormal sensations or numbness in the feet. Many patients wearing new shoes or stepping on sharp objects inadvertently can lead to diabetic foot. The fourth cause is infection induced by patients who initially neglect minor foot injuries, or who improperly manage such injuries at home, leading to the development of diabetic foot. Therefore, we advise diabetics to maintain good control of their blood sugar and take timely measures to prevent diabetic foot.

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Written by Luo Han Ying
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Where to massage for diabetic foot

For diabetic patients, we do not recommend foot therapy. Why is that? First, the foot therapy institutions outside are not very professional; many individuals start working without proper training. The massage might lack strength, and the hygiene standards are often not met, which can lead to local injuries and infections. Second, diabetic patients have a specific bodily constitution due to high blood sugar levels, making their tissues particularly susceptible to damage. Once damaged, these tissues do not heal easily. If the hygiene is substandard, the feet of diabetic patients are especially prone to infection. Diabetic foot patients, because of poor blood supply, are also more susceptible to fungal infections. Therefore, given these factors, it is advised that diabetic patients avoid foot therapy.

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Written by Chen Li Ping
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incidence of gestational diabetes

Gestational diabetes refers to diabetes that appears or is diagnosed during pregnancy, or any degree of glucose tolerance abnormality, which is classified as an independent type of diabetes. Diabetes combined with pregnancy or gestational diabetes can pose serious risks to the health of both mother and child. Before national screening of blood sugar levels during pregnancy was initiated, the detection rate of gestational diabetes was not very high, only 0.24%. However, with the widespread implementation of blood sugar screening during pregnancy, the current incidence rate of gestational diabetes is approximately 1% to 5%.